Compound Summary

  Compound Information

TCMBANKIN000003

药名:	rotenone
别名:	rotenone
分子式:	C23H22O6
Smiles:	CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC
成分:	HBIN042466
TCMID_id:	18924
PubChem_id:	6758

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004176	Derris elliptica	毛鱼藤
TCMBANKHE005558	Pachyrrhizus erosus	豆薯			To clear lung and engender liquid, disinhibit urine and free milk, resolve liquor toxin./Lung heat cough, pulmonary welling abscess, summerheat stroke with vexation and thirst, diabetes mellitus, scant breast milk, inhibited urination [=dysuria].
TCMBANKHE005641	Millettia reticulata	鸡血藤根			To quiet spirit, calm./Manic agitation schizophrenia.
TCMBANKHE008819	Tephrosia purpurea	灰叶根			To clear heat and disperse stagnation, move qi and relieve pain, contract damp and relieve itch./Indigestion, gastritis, abdominal distention, stomachache, eczema, dermatitis.
TCMBANKHE007894	Derris trifoliata	鱼藤			To dissipate stasis and relieve pain, kill worms and relieve itch./Painful swelling from knocks and falls, lichen.
TCMBANKHE006292/YNS-298/YEM-187/XU-40/XU-99	Verbascum thapsus|Verbascum thapsus L|Verbascum thapsus L.	毛蕊花	一柱香	云南药材标准：第六册|云南民族药物志：第一卷|云南省昆明市盘龙区	清热解毒，活血止血。用于肺热咳嗽，湿热痹痛，肠痈，疮毒，湿疹，跌打扭伤，创伤出血。|To clear heat and resolve toxin, stanch bleeding and dissipate stasis./Pneumonia, chronic appendicitis, sore toxin, sprain from knocks and falls, bleeding due to external injury.	白族/傈僳族/纳西族/彝族/藏族
TCMBANKHE008066/YEM-321	Pachyrhizus erosus|Pachyrhizus erosus (L.)Urb.	地瓜子|豆薯	豆薯	云南民族药物志：第二卷	To kill worms and relieve itch./Scab and lichen, itchy skin, swollen welling abscess.	傣族
TCMBANKHE008340/YEM-321	Pachyrhizus erosus|Pachyrhizus erosus (L.)Urb.	地瓜子|豆薯	豆薯	云南民族药物志：第二卷	To kill worms and relieve itch./Scab and lichen, itchy skin, swollen welling abscess.	傣族
TCMBANKHE008805/YEM-805/XU-448	Millettia pachycarpa|Millettia pachycarpa Benth.	苦檀子|厚果崖豆藤	冲天子	云南民族药物志：第四卷|云南省昭通市盐津县普洱镇	To attack toxin and relieve pain, disperse accumulation and kill worms./Scab and lichen, sore lai, sand qi abdominal pain, child gan accumulation.	布依族/傈僳族/彝族/藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000002	Hyperalgesia	phenotype	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	22244441
TCMBANKDI000019	Parkinson Disease	disease	Nervous System Diseases	21383081
TCMBANKDI000045	Neurotoxicity Syndromes	group	Nervous System Diseases; Chemically-Induced Disorders	21742033
TCMBANKDI000054	Alzheimer's Disease	disease	Nervous System Diseases; Mental Disorders	22229260
TCMBANKDI000088	Lung Neoplasms	group	Neoplasms; Respiratory Tract Diseases	25522273
TCMBANKDI006012	Neuralgia	phenotype	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	22244441
TCMBANKDI012119	Nerve Degeneration	phenotype	Pathological Conditions, Signs and Symptoms	21742033
TCMBANKDI028007	Demyelinating Diseases	group	Nervous System Diseases	23816754

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000199	ICAM1	BB2; CD54; P3.58	intercellular adhesion molecule 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000222	EDN1	ARCND3; ET1; HDLCQ7; PPET1; QME	endothelin 1
TCMBANKGE000330	HMOX1	HMOX1D; HO-1; HSP32; bK286B10	heme oxygenase 1
TCMBANKGE000382	PARK7	DJ-1; DJ1; GATD2; HEL-S-67p	Parkinsonism associated deglycase
TCMBANKGE000639	HRAS	C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; RASH1; p21ras	HRas proto-oncogene, GTPase
TCMBANKGE000735	VDAC1	PORIN; VDAC-1	voltage dependent anion channel 1
TCMBANKGE000747	GAPDH	G3PD; GAPD; HEL-S-162eP	glyceraldehyde-3-phosphate dehydrogenase
TCMBANKGE000898	MYC	MRTL; MYCC; bHLHe39; c-Myc	MYC proto-oncogene, bHLH transcription factor
TCMBANKGE001045	CCND1	BCL1; D11S287E; PRAD1; U21B31	cyclin D1
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001076	SOD2	GClnc1; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD	superoxide dismutase 2
TCMBANKGE001118	MMP9	CLG4B; GELB; MANDP2; MMP-9	matrix metallopeptidase 9
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001176	CAT	-	catalase
TCMBANKGE001203	MAPK1	ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK	mitogen-activated protein kinase 1
TCMBANKGE001794	RAP2A	K-REV; KREV; RAP2; RbBP-30	RAP2A, member of RAS oncogene family
TCMBANKGE005732	SYN1	MRX50; SYN1a; SYN1b; SYNI	synapsin I
TCMBANKGE009236	SLC5A1	D22S675; NAGT; SGLT1	solute carrier family 5 member 1
TCMBANKGE013582	SOD3	EC-SOD	superoxide dismutase 3