Compound Summary

  Compound Information

TCMBANKIN000005

药名:	tetrodotoxin
分子式:	C11H17N3O8
Smiles:	C(C1(C2C3C(N=C(NC34C(C1OC(C4O)(O2)O)O)N)O)O)O
成分:	HBIN046126
TCMID_id:	21195
PubChem_id:	139251219
DrugBank_id:	DB05232

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE007959

Fugu ocellatus

河豚

To supplement liver and kidney, dispel damp and relieve pain./Impotence, enuresis, dizziness, limp aching lumbus and knees, wind-damp impediment pain, itchy skin.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000002	Hyperalgesia	phenotype	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	27013358
TCMBANKDI000004	Chronic pain	phenotype	Pathological Conditions, Signs and Symptoms	30648289
TCMBANKDI000021	Stress, Psychological	disease	Behavior and Behavior Mechanisms	27013358
TCMBANKDI000056	Heart failure	disease	Cardiovascular Diseases	25424392
TCMBANKDI000093	Sepsis	disease	Pathological Conditions, Signs and Symptoms; Infections	24669759
TCMBANKDI000095	Pain	phenotype	Pathological Conditions, Signs and Symptoms	30765606
TCMBANKDI000921	Blood Pressure	phenotype	-	23570977
TCMBANKDI005044	Ventricular Remodeling	phenotype	Pathological Conditions, Signs and Symptoms	29097069
TCMBANKDI011475	Status Epilepticus	disease	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	28860087
TCMBANKDI011774	Brain Waves	phenotype	-	30228120
TCMBANKDI012645	Myotonia Congenita	disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases	28833464
TCMBANKDI014716	Epilepsy, Temporal Lobe	disease	Nervous System Diseases	28860087
TCMBANKDI015485	Schizophrenia	disease	Mental Disorders	26819276
TCMBANKDI015830	Myocardial Ischemia	disease	Cardiovascular Diseases	29509584
TCMBANKDI016616	Interstitial Cystitis	disease	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases	30157135
TCMBANKDI018581	Gliosis	phenotype	Pathological Conditions, Signs and Symptoms	24740847
TCMBANKDI020247	Cardiomegaly	phenotype	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases	23570977
TCMBANKDI021084	Bladder pain syndrome	disease	-	30157135
TCMBANKDI023555	Hypoxia	phenotype	Pathological Conditions, Signs and Symptoms	27383588
TCMBANKDI029054	Neurodevelopmental Disorders	group	Mental Disorders	26819276
TCMBANKDI030645	Photophobia	phenotype	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases	26086898

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000054	GAD1	CPSQ1; GAD; SCP	glutamate decarboxylase 1
TCMBANKGE000055	Ntf5	2900040K06Rik; AI462899; NT-4; NT-5; NT4; NT4/5; Ntf-5; Ntf4	neurotrophin 5
TCMBANKGE000056	SLC8B1	NCKX6; NCLX; SLC24A6	solute carrier family 8 member B1
TCMBANKGE000057	MCU	C10orf42; CCDC109A; HsMCU	mitochondrial calcium uniporter
TCMBANKGE000058	SCN4A	CMS16; HOKPP2; HYKPP; HYPP; NAC1A; Na(V)1.4; Nav1.4; SkM1	sodium voltage-gated channel alpha subunit 4
TCMBANKGE000059	NGFR	CD271; Gp80-LNGFR; TNFRSF16; p75(NTR); p75NTR	nerve growth factor receptor
TCMBANKGE000060	CRHR1	CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1L	corticotropin releasing hormone receptor 1
TCMBANKGE000061	OXTR	OT-R	oxytocin receptor
TCMBANKGE000062	SCN1A	EIEE6; FEB3; FEB3A; FHM3; GEFSP2; HBSCI; NAC1; Nav1.1; SCN1; SMEI	sodium voltage-gated channel alpha subunit 1
TCMBANKGE000063	SCN8A	BFIS5; CERIII; CIAT; EIEE13; MED; MYOCL2; NaCh6; Nav1.6; PN4	sodium voltage-gated channel alpha subunit 8
TCMBANKGE000064	SCN3A	EIEE62; FFEVF4; NAC3; Nav1.3	sodium voltage-gated channel alpha subunit 3
TCMBANKGE000065	SCN9A	ETHA; FEB3B; GEFSP7; HSAN2D; NE-NA; NENA; Nav1.7; PN1; SFNP	sodium voltage-gated channel alpha subunit 9
TCMBANKGE000106	SCN10A	FEPS2; Nav1.8; PN3; SNS; hPN3	sodium voltage-gated channel alpha subunit 10
TCMBANKGE000171	DNMT1	ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI	DNA methyltransferase 1
TCMBANKGE000224	AGT	ANHU; SERPINA8; hFLT1	angiotensinogen
TCMBANKGE000235	NTRK2	EIEE58; GP145-TrkB; OBHD; TRKB; trk-B	neurotrophic receptor tyrosine kinase 2
TCMBANKGE000236	BDNF	ANON2; BULN2	brain derived neurotrophic factor
TCMBANKGE000237	CAMK2G	CAMK; CAMK-II; CAMKG; MRD59	calcium/calmodulin dependent protein kinase II gamma
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000356	SLC12A2	BSC; BSC2; NKCC1; PPP1R141	solute carrier family 12 member 2
TCMBANKGE000985	GABRG1	-	gamma-aminobutyric acid type A receptor subunit gamma1
TCMBANKGE000997	GCG	GLP-1; GLP1; GLP2; GRPP	glucagon