Compound Summary


  Compound Information

药名:

evodiamine

别名:

l-Evodiamine; BDBM50366821; BB_NC-1930; ZINC00898159; Evodiamine, Evodia rutaecarpa; evodiamine ; 518-17-2; CHEMBL486598; Evodiamine; ZINC2031813; C09187

分子式:

C19H17N3O

Smiles:

CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3

成分:

HBIN026264

CAS_id:

518-17-2

SymMap_id:

SMIT01413;SMIT05956

TCMID_id:

7664

TCMSP_id:

MOL003958

PubChem_id:

442088


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000518 少果吴茱萸
TCMBANKHE001184 毛脉吴茱萸
TCMBANKHE002173 Stigma Croci 西红花 To activate blood circulation and eliminate blood stasis, to remove heat from blood and counteract toxicity, and to calm the nerves./Treatment of amenrrhea with abdominal mass formation, blood stasis after childbirth, eruptions in infectious diseases, emotional dejection, mania.
TCMBANKHE003083 吴茱萸叶
TCMBANKHE003391 Evodia baberi 一花吴茱萸
TCMBANKHE006061 Fructus Evodiae 吴茱萸 1. To dispel cold and stop pain; 2. To pacify the liver and direct rebellious qi downward; 3. To stop vomiting/Dysentery, cold pain in stomach duct and abdomen, reverting yin headache, mounting qi , dysmenorrhea, beriberi with edema, hyperchlorhydria, cold-damp diarrhea.
TCMBANKHE006128 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE007708 Evodia austrosinensis 华南吴茱萸
TCMBANKHE009154 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE007462 青风藤 Wind-damp impediment pain, pain from arthritis, swelling in joints, paralytic and pruritus.
TCMBANKHE004506/YEM-137 Radix Notoginseng|Panax notoginseng (Burk.) F, H. Chen ex C.Chow et al. 三七 三七 云南民族药物志:第一卷 To eliminate blood stasis, arrest bleeding, cause subsidence of swelling and alleviate pain./Hemoptysis, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, bleeding due to external injury, angina pectoris, stabbing pain in chest and abdomen, painful swelling from knocks and falls. 彝族
TCMBANKHE004189/YEM-163 Evodia rutaecarpa var. officinalis|Evodia rutaecarpa (Juss.) Benth. 石斛果|吴茱萸 吴茱萸 云南民族药物志:第一卷 See Evodia rutaecarpa ./See Evodia rutaecarpa. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE008832/YEM-163 Evodia rutaecarpa var. bodinieri|Evodia rutaecarpa (Juss.) Benth. 波士吴茱萸|吴茱萸 吴茱萸 云南民族药物志:第一卷 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE000949/YEM-163 Evodia rutaecarpa (Juss.) Benth. 吴茱萸根|吴茱萸 吴茱萸 云南民族药物志:第一卷 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE002126/YEM-163 Fructus Evodiae|Evodia rutaecarpa (Juss.) Benth. 吴芋|吴茱萸 吴茱萸 云南民族药物志:第一卷 Treatment of headache accompanied by retching and cold limbs, abdominal colic, weakness and edema of the legs, abdominal pain during menstruation, epigastric distension and pain with vomiting and acid regurgitation, diarrhea occurring before dawn daily, hypertension. External use for ulcers in the mouth./1. Its volatile oil containing evoden inhibits the abnormal fermentation in the intestine.2. Evodin, evodiamine and rutaecarpine, are active components for analgesic.3. Oral administration or injection can lower blood pressure in normal animals or those with renal hypertension. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI015307 Coronary Artery Disease disease Cardiovascular Diseases 23025809
TCMBANKDI015496 Liver neoplasms group Digestive System Diseases; Neoplasms 23032719
TCMBANKDI021229 Fatty Liver disease Digestive System Diseases 23025809
TCMBANKDI032496 Hyperlipidemia disease Nutritional and Metabolic Diseases 23025809

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000297 JAK2 JTK10; THCYT3 Janus kinase 2
TCMBANKGE000764 TRPV1 VR1 transient receptor potential cation channel subfamily V member 1
TCMBANKGE001114 IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 interleukin 6
TCMBANKGE001171 SRC ASV; SRC1; THC6; c-SRC; p60-Src SRC proto-oncogene, non-receptor tyrosine kinase
TCMBANKGE001178 STAT3 ADMIO; ADMIO1; APRF; HIES signal transducer and activator of transcription 3
TCMBANKGE001201 MAPK3 ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK mitogen-activated protein kinase 3
TCMBANKGE001203 MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK mitogen-activated protein kinase 1