Compound Summary

  Compound Information

TCMBANKIN000013

药名:	bufalin
分子式:	C24H34O4
Smiles:	CC12CCC(CC1CCC3C2CCC4(C3(CCC4C5=COC(=O)C=C5)O)C)O
成分:	HBIN018981
TCMID_id:	2716
PubChem_id:	137705150

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE005508	Bufo bufo gargarizans, Bufo melanostictus	蟾酥			To resolve toxin, relieve pain, open orifices and arouse spirit./Welling abscess and flat abscess with clove sores, swelling pain in throat, summerheat stroke with vomiting and diarrhea, abdominal pain and clouded spirit, local anesthesia.
TCMBANKHE006275	Bufo bufo gargarizans, Bufo melanostictus	蟾蜍			To resolve toxin and dissipate binds, disperse accumulation and disinhibit water, kill worms and disperse gan ./Welling abscess and flat abscess, clove sore, effusion of back, scrofula, malign sore, concretion and accumulation, ascites, edema, child gan accumulation, tetanus, chronic cough and asthma.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000005	Autoimmune Diseases	group	Immune System Diseases	21076398
TCMBANKDI000009	Glioma	disease	Neoplasms	30739221
TCMBANKDI000086	Colonic Neoplasms	group	Digestive System Diseases; Neoplasms	21763418
TCMBANKDI007361	Multiple Myeloma	disease	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases	28492559

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000047	AKT1	AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA	AKT serine/threonine kinase 1
TCMBANKGE000052	TNF	DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F	tumor necrosis factor
TCMBANKGE000053	NFKB1	CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB	nuclear factor kappa B subunit 1
TCMBANKGE000092	DDX58	RIG-I; RIG1; RIGI; RLR-1; SGMRT2	DExD/H-box helicase 58
TCMBANKGE000093	IFNB1	IFB; IFF; IFN-beta; IFNB	interferon beta 1
TCMBANKGE000094	NR5A1	AD4BP; ELP; FTZ1; FTZF1; POF7; SF-1; SF1; SPGF8; SRXX4; SRXY3; hSF-1	nuclear receptor subfamily 5 group A member 1
TCMBANKGE000095	CYP11B2	ALDOS; CPN2; CYP11B; CYP11BL; CYPXIB2; P-450C18; P450C18; P450aldo	cytochrome P450 family 11 subfamily B member 2
TCMBANKGE000096	TBK1	FTDALS4; IIAE8; NAK; T2K	TANK binding kinase 1
TCMBANKGE000097	IRF3	IIAE7	interferon regulatory factor 3
TCMBANKGE000098	ATP1A4	ATP1A1; ATP1AL2	ATPase Na+/K+ transporting subunit alpha 4
TCMBANKGE000191	GUCY2C	DIAR6; GC-C; GUC2C; MECIL; MUCIL; STAR	guanylate cyclase 2C
TCMBANKGE000269	ATG5	APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5	autophagy related 5
TCMBANKGE000362	DNAH8	ATPase; hdhc9	dynein axonemal heavy chain 8
TCMBANKGE000369	IFNA1	IFL; IFN; IFN-ALPHA; IFN-alphaD; IFNA13; IFNA@; leIF D	interferon alpha 1
TCMBANKGE000664	ATP1A3	AHC2; ATP1A1; CAPOS; DYT12; RDP	ATPase Na+/K+ transporting subunit alpha 3
TCMBANKGE001016	ATP1A1	CMT2DD; HOMGSMR2	ATPase Na+/K+ transporting subunit alpha 1
TCMBANKGE001106	MTOR	FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS	mechanistic target of rapamycin kinase
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE001177	TP53	BCC7; BMFS5; LFS1; P53; TRP53	tumor protein p53
TCMBANKGE001198	BECN1	ATG6; VPS30; beclin1	beclin 1
TCMBANKGE001201	MAPK3	ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK	mitogen-activated protein kinase 3
TCMBANKGE001203	MAPK1	ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK	mitogen-activated protein kinase 1