Compound Summary

  Compound Information

TCMBANKIN000015

药名:	brefeldin a
别名:	(7S,15S,1R)-2,15-dihydroxy-7-methyl-6-oxabicyclo[11.3.0]hexadeca-3,11-dien-5-o ne; AC1O5L8S; AKOS024282481; SR-01000597412-1; MolPort-004-955-162; NCGC00025061-02; UPCMLD-DP095:002; NCGC00025061-03; IDI1_033950; (2E,7S,10E,12R,13R,15S)-12,15-dihydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one; SR-01000597412; HMS1361J22; 1,6,7,8,9,11a?,12,13,14,14?a-Decahydro-1?,13?-dihydroxy-6?-methyl-4H-cyclopent(f)oxacyclotridecin-4-one; ST056354; UPCMLD-DP095; 4H-Cyclopent(f)oxacyclotridecin-4-one,1,6,7,8,9,11a-beta,12,13,14,14a-alpha-decahydro-1-beta-13-alpha-dihydroxy-6-beta-methyl-; LS-58416; CCG-208020; NSC-89671; NSC 56310; 1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one; (1R,6S,13S,14AR)-1,13-DIHYDROXY-6-METHYL-1H,6H,7H,8H,9H,11AH,12H,13H,14H,14AH-CYCLOPENTA[F]OXACYCLOTRIDECAN-4-ONE; HMS1989J22; 4H-Cyclopent(f)oxacyclotridecin-4-one, 1,6,7,8,9,11a-beta,12,13,14,14a-alpha-decahydro-1-beta-13-alpha-dihydroxy-6-beta-methyl-; NCGC00017254-03; CHEMBL1572153; HMS3402J22; HMS1791J22; UPCMLD-DP095:001; NCGC00017254-04; brefeldin A; Cyanaein; G405; 20350-15-6; SCHEMBL12648486; Cyanein; BSPBio_001480; Decumbin; (+)-Brefeldin A, Eupenicillium brefeldianum; C16H24O4
分子式:	C16H24O4
Smiles:	CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O
成分:	HBIN018821
SymMap_id:	SMIT14500
TCMID_id:	2600
PubChem_id:	6436187
DrugBank_id:	DB07348

---

   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000232		川射干
TCMBANKHE004258	Radix Angelicae sinensis	当归根			To enrich blood, activate blood circulation, regulate menstruation, relieve pain, and relax bowels./Women’s diseases, blood deficiency syndrome, menstrual disorder, amenorrhea and dysmenorrhea, dysmenorrhea due to anemia, thrombophlebitis, neuralgia, arthritis, chronic nephritis, constrictive aortitis, blood vaculty, pernicious anemia, anemia due to folic acid deficiency, dysentery, hepatitis, Raynaud’s disease, lumbago, various pains due to blood stasis and rheumatic impediment, sores, welling abscess, constipation, ulcer in gastrointestinal tract, skin diseases, eczema, dermatitis, neurodermatitis, psoriasis.

---

   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000008	Brain Neoplasms	group	Neoplasms; Nervous System Diseases	29155422
TCMBANKDI000009	Glioma	disease	Neoplasms	29155422
TCMBANKDI000047	Neoplasm Metastasis	phenotype	Pathological Conditions, Signs and Symptoms; Neoplasms	27065333
TCMBANKDI000085	Inflammation	phenotype	Pathological Conditions, Signs and Symptoms	24198377
TCMBANKDI000088	Lung Neoplasms	group	Neoplasms; Respiratory Tract Diseases	25011082
TCMBANKDI002742	Polycystic Kidney Diseases	group	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases	24627348
TCMBANKDI007361	Multiple Myeloma	disease	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases	28211573
TCMBANKDI015740	Colorectal Neoplasms	group	Digestive System Diseases; Neoplasms	30668917
TCMBANKDI023555	Hypoxia	phenotype	Pathological Conditions, Signs and Symptoms	29155422

---

   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000047	AKT1	AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA	AKT serine/threonine kinase 1
TCMBANKGE000105	KIF5B	HEL-S-61; KINH; KNS; KNS1; UKHC	kinesin family member 5B
TCMBANKGE000106	SCN10A	FEPS2; Nav1.8; PN3; SNS; hPN3	sodium voltage-gated channel alpha subunit 10
TCMBANKGE000107	ARFGEF3	A7322; BIG3; C6orf92; KIAA1244; PPP1R33; dJ171N11.1	ARFGEF family member 3
TCMBANKGE000108	COMP	EDM1; EPD1; MED; PSACH; THBS5; TSP5	cartilage oligomeric matrix protein
TCMBANKGE000250	CCL5	D17S136E; RANTES; SCYA5; SIS-delta; SISd; TCP228; eoCP	C-C motif chemokine ligand 5
TCMBANKGE000274	CCL2	GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF	C-C motif chemokine ligand 2
TCMBANKGE000553	GDF10	BIP; BMP-3b; BMP3B	growth differentiation factor 10
TCMBANKGE000696	PKD1	PBP; PC1; Pc-1; TRPP1	polycystin 1, transient receptor potential channel interacting
TCMBANKGE001027	STK11	LKB1; PJS; hLKB1	serine/threonine kinase 11
TCMBANKGE001050	PKD2	APKD2; PC2; PKD4; Pc-2; TRPP2	polycystin 2, transient receptor potential cation channel
TCMBANKGE001068	CXCL1	FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1	C-X-C motif chemokine ligand 1
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE001148	VEGFA	MVCD1; VEGF; VPF	vascular endothelial growth factor A