Compound Summary


  Compound Information

药名:

colchicine

别名:

LS-187917

分子式:

C22H25NO6

Smiles:

CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC

成分:

HBIN021260

CAS_id:

64-86-8

SymMap_id:

SMIT01348

TCMID_id:

3911

PubChem_id:

6167


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000067 萱草嫩苗
TCMBANKHE000548 百合花
TCMBANKHE004340 萱草根 Edema, jaundice, strangury-turbidity, vaginal discharge, spontaneous external bleeding, hematochezia, flooding and spotting, scrofula, mammary welling abscess, galactostasis.
TCMBANKHE001557 小黄花菜
TCMBANKHE002191 百合子
TCMBANKHE002472 金针菜
TCMBANKHE003826 Rhizoma Cimicifugae 升麻 To induce perspiration and promote eruption, to remove toxic heat, and to cure drooping and ptosis./Prevention of ptosis, women’s hormone dysfunction diseases, seasonal epidemic fire toxin, mouth sore, sore pharynx, macula, cold-heat headache, swelling toxin of welling abscess and sore, center qi fall, spleen vacuity diarrhea, chronic dysentery, vaginal discharge, flooding.
TCMBANKHE004018 Pseudobulbus Cremastrae seu Pleiones;Asarum sagittarioides 山慈菇 To remove toxic heat, and to dissolve lumps./Common cold, stomachache, toothache, knocks and falls, snake bite.
TCMBANKHE005920 Colchicum autumnale 秋水仙
TCMBANKHE004399 Veratrum nigrum 藜芦 To promote vomiting, dispel wind and transform phlegm, lower blood pressure, kill worms./Wind stroke with congesting phlegm, epilepsy, malaria, scab and lichen, malign sore.
TCMBANKHE005500 Arisaema curvatum 弯曲天南星
TCMBANKHE006371 白屈菜 Pain in sensory nerve endings, pain from ulcer in digestive tract, stomachache, abdominal pain, enteritis, dysentery, chronic bronchitis, pertussis, cough, jaundice, edema, ascites, scab and lichen with swelling of sores, snake or insect bites.
TCMBANKHE005954 Radix Pulsatillae 白头翁 1. To clear heat and release toxins; 2. To cool the blood and stop dysentery/Amebic dysentery, nosebleed, flooding and spotting, bleeding from hemorrhoids, cold-heat warm malaria, vaginal discharge, pudendal itch, eczema, scrofula, welling abscess, painful red eyes, neurodermatitis.
TCMBANKHE007163 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE006400 Semen Cucurbitae moschatae 南瓜子 To kill parasites/Taeniasis, ascariasis, bilharziosis, ancylostomiasis, oxyuria disease, postpartum scant milk, postpartum edema, pertussis, hemorrhoids.
TCMBANKHE008975 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE006792 Lepidium sativum 家独行菜 To relieve cough and dispel phlegm, warm center, disinhibit urine, hasten delivery./Cough, asthma, abundant phlegm, hiccough, diarrhea, dysentery, abdominal distention, edema, inhibited urination, scab and lichen.
TCMBANKHE006911 Hemerocallis minor 小萱草根 See Hemerocallis fulva./See Hemerocallis fulva.
TCMBANKHE007331 Tulipa edulis 光慈姑 To clear heat and resolve toxin, dissipate binds and disperse swelling./Swelling pain in throat, scrofula, welling abscess and flat abscess, swelling of sores, postpartum stasis stagnation.
TCMBANKHE008976 Bulbus Lilii 川百合 1. To moisurize the lung and relieve cough (lung-dryness with cough and hemoptysis). 2. To relieve cardiac heat and tranquilize the mind (convalescence of febrile diseases or yin-deficiency with heat manifested as irritability, insomnia, dreaminess, palpitation and absent-mindedness)./1. To moisurize the lung and relieve cough (lung-dryness with cough and hemoptysis). 2. To relieve cardiac heat and tranquilize the mind (convalescence of febrile diseases or yin-deficiency with heat manifested as irritability, insomnia, dreaminess, palpi
TCMBANKHE004917/YNS-146 Iphigenia indica|Iphigenia indica Kunth 草贝母|山慈菇 丽江山慈菇 云南药材标准:第二册 清热解毒,消肿散结。用于痛风,手足关节红肿疼痛,疮疡肿毒,瘰疬结核,虫蛇咬伤|To dissipate binds and relieve pain./Carcinoma of mammary glands, nasopharyngeal carcinoma, carcinoma of salivary gland, scrofula, swelling of skin, pain wind.
TCMBANKHE000196/YEM-180 Bulbus Lilii Preparata|Lilium brownii F. E. Brown. ex Miellez 炙百合|百合 野百合 云南民族药物志:第一卷 1. To moisurize the lung and relieve cough (lung-dryness with cough and hemoptysis). 2. To relieve cardiac heat and tranquilize the mind (convalescence of febrile diseases or yin-deficiency with heat manifested as irritability, insomnia, dreaminess, palpitation and absent-mindedness)./1. To moisurize the lung and relieve cough (lung-dryness with cough and hemoptysis). 2. To relieve cardiac heat and tranquilize the mind (convalescence of febrile diseases or yin-deficiency with heat manifested as irritability, insomnia, dreaminess, palpi 哈尼族/傈僳族/彝族
TCMBANKHE001627/YEM-744/XU-850 Radix et Rhizoma Rhei Praeparata|Rheum palmatum L.|Rheum palmatum 制大黄|掌叶大黄 掌叶大黄 云南民族药物志:第四卷|西藏昌都地区芒康县 Treatment of fever with constipation, retention of the feces and abdominal pain, dysentery with inadequate discharge from the bowels, jaundice caused by damp-heat, haematemesis, epistaxis, inflammation of eye and swelling of the throat due to heat in the blood, appendicitis with abdominal pain, boils, sores and abscess, amenorrhea due to blood stasis, traumatic injuries, hemorrhage from the upper gastrointestinal tract. External use for scalds and burns.Radixet Rhizoma Rhei (stir-fried with wine) Inflammation of the eye, swelling of the throat and painful swelling of the gums. Radix et Rhizoma Rhei (prepared) Boils, sores and abscess. Radix et Rhizoma Rhei (carbonized) Hemorrhage with blood stasis due to heat in the blood./1. Sennoside A is the component for purgation.2. Promoting biliary secretion and enhancing the amount of bilirubin and bile acid.3. Rhein and Emodin exert bacteriostatic effect by inhibting the synthesis of DNA, RNA and protein in bacteria4. Emodin is a component for hypotensive5. Oral use of its extract reduces the raio of serum cholesterol and total phospholipid in rabbits with hypercholesterolemia.6. Chrysophanol, an other active component, exerts a hemostatic effect. 阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族
TCMBANKHE004314/YEM-77 Gloriosa superba|Gloriosa superba L. 嘉兰 嘉兰 云南民族药物志:第一卷 Hemiplegia, general arthralgia, convulsion due to high fever, whole body swelling. 阿昌族/傣族/德昂族/景颇族/傈僳族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000026 Obesity disease Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 30869182
TCMBANKDI000027 Cardiovascular Diseases group Cardiovascular Diseases 31733140
TCMBANKDI000056 Heart failure disease Cardiovascular Diseases 24720919
TCMBANKDI000063 Atrial Fibrillation disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 25172965
TCMBANKDI000078 Skin Neoplasms group Neoplasms; Skin and Connective Tissue Diseases 29862491
TCMBANKDI000085 Inflammation phenotype Pathological Conditions, Signs and Symptoms 22090167
TCMBANKDI000958 Pericarditis disease Cardiovascular Diseases 23992557
TCMBANKDI004886 Gout disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases 31666237
TCMBANKDI005094 Angina Pectoris phenotype Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 31733140
TCMBANKDI011682 Acute Coronary Syndrome disease Cardiovascular Diseases 23265346
TCMBANKDI013351 Postpericardiotomy Syndrome phenotype Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 25172965
TCMBANKDI015307 Coronary Artery Disease disease Cardiovascular Diseases 29055633
TCMBANKDI016428 Plaque, Atherosclerotic phenotype Pathological Conditions, Signs and Symptoms 23265346
TCMBANKDI019632 Myocardial Infarction disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 31733140
TCMBANKDI020657 Gastrointestinal Diseases group Digestive System Diseases 25172965
TCMBANKDI021740 Primary biliary cirrhosis disease Pathological Conditions, Signs and Symptoms; Digestive System Diseases 21699802
TCMBANKDI022369 Melanoma, Experimental disease Neoplasms 21689407
TCMBANKDI028185 Behcet Syndrome disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases 22632542
TCMBANKDI029255 Postoperative Complications group Pathological Conditions, Signs and Symptoms 25172965
TCMBANKDI030421 Pericardial effusion disease Cardiovascular Diseases 25172965

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000051 IL1B IL-1; IL1-BETA; IL1F2; IL1beta interleukin 1 beta
TCMBANKGE000215 AMH MIF; MIS anti-Mullerian hormone
TCMBANKGE000216 Hsp84-3 84kDa; Hsp90; hsp3 heat shock protein, 3
TCMBANKGE000217 P2RX7 P2X7 purinergic receptor P2X 7
TCMBANKGE000218 P2RX2 DFNA41; P2X2 purinergic receptor P2X 2
TCMBANKGE000238 IL10 CSIF; GVHDS; IL-10; IL10A; TGIF interleukin 10
TCMBANKGE000261 INS IDDM; IDDM1; IDDM2; ILPR; IRDN; MODY10; PNDM4 insulin
TCMBANKGE000318 HMGB1 HMG-1; HMG1; HMG3; SBP-1 high mobility group box 1
TCMBANKGE000554 CRP PTX1 C-reactive protein
TCMBANKGE000729 CASP1 ICE; IL1BC; P45 caspase 1
TCMBANKGE000741 HSPA1B HSP70-1; HSP70-1B; HSP70-2; HSP70.1; HSP70.2; HSP72; HSPA1; HSX70 heat shock protein family A (Hsp70) member 1B
TCMBANKGE001052 NLRP3 AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; FCU; KEFH; MWS; NALP3; PYPAF1 NLR family pyrin domain containing 3
TCMBANKGE001068 CXCL1 FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 C-X-C motif chemokine ligand 1
TCMBANKGE001114 IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 interleukin 6
TCMBANKGE001127 PRKAA1 AMPK; AMPKa1 protein kinase AMP-activated catalytic subunit alpha 1
TCMBANKGE001128 PRKAA2 AMPK; AMPK2; AMPKa2; PRKAA protein kinase AMP-activated catalytic subunit alpha 2