Compound Summary

  Compound Information

TCMBANKIN000039

药名:	Zerumbone
别名:	zerumbone; NSC698299; zerumbone ; 2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one; AIDS051828; 2,6,10-Cycloundecatrien-1-one, 2,6,9,9-tetramethyl-, (E,E,E)-; (E,E,E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one; 471-05-6; (2E,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one; AIDS-051828; (2E,6E,10E)-2,6,9,9-tetramethyl-1-cycloundeca-2,6,10-trienone; 2,6,9 humulatriene-8-one
分子式:	C15H22O
Smiles:	CC1=CCC(C=CC(=O)C(=CCC1)C)(C)C
成分:	HBIN048883
OB_score:	49.758812
CAS_id:	471-05-6
SymMap_id:	SMIT06255
TCMID_id:	22968
TCMSP_id:	MOL004314
PubChem_id:	5470187

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE008098	Radix Curcumae	郁金			1. To invigorate blood and stop pain; 2. To promote qi circulation and release stagnation; 3. To cool blood and clear heat in the heart; 4. To relieve jaundice and facilitate gall bladder function/See Curcuma longa.
TCMBANKHE006477	Zingiber aromaticum	芳香姜
TCMBANKHE008925	Syringa pinnafolia	羽叶丁香			To warm center, downbear qi , warm kidney./Cold pain in stomach duct and abdomen, cold asthma, prolapse of uterus, prolapse of rectum.
TCMBANKHE003992/YEM-503	Zingiber zerumbet|Zingiber zerumbet(L.)Smith	红球姜	红球姜	云南民族药物志：第三卷		阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI026275

Glioblastoma

disease

Neoplasms

23035900

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000047	AKT1	AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA	AKT serine/threonine kinase 1
TCMBANKGE000135	CXCR4	CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS	C-X-C motif chemokine receptor 4
TCMBANKGE000199	ICAM1	BB2; CD54; P3.58	intercellular adhesion molecule 1
TCMBANKGE000214	SCD	FADS5; MSTP008; SCD1; SCDOS; hSCD1	stearoyl-CoA desaturase
TCMBANKGE000330	HMOX1	HMOX1D; HO-1; HSP32; bK286B10	heme oxygenase 1
TCMBANKGE000695	MAPK13	MAPK 13; MAPK-13; PRKM13; SAPK4; p38delta	mitogen-activated protein kinase 13
TCMBANKGE000809	BIRC3	AIP1; API2; CIAP2; HAIP1; HIAP1; IAP-1; MALT2; MIHC; RNF49; c-IAP2	baculoviral IAP repeat containing 3
TCMBANKGE000810	BIRC2	API1; HIAP2; Hiap-2; MIHB; RNF48; c-IAP1; cIAP1	baculoviral IAP repeat containing 2
TCMBANKGE000820	CFLAR	CASH; CASP8AP1; CLARP; Casper; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT; c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; cFLIP	CASP8 and FADD like apoptosis regulator
TCMBANKGE000898	MYC	MRTL; MYCC; bHLHe39; c-Myc	MYC proto-oncogene, bHLH transcription factor
TCMBANKGE000899	GLI2	CJS; HPE9; PHS2; THP1; THP2	GLI family zinc finger 2
TCMBANKGE000909	GLI1	GLI; PAPA8; PPD1	GLI family zinc finger 1
TCMBANKGE001010	TNFRSF10A	APO2; CD261; DR4; TRAILR-1; TRAILR1	TNF receptor superfamily member 10a
TCMBANKGE001013	BIRC5	API4; EPR-1	baculoviral IAP repeat containing 5
TCMBANKGE001045	CCND1	BCL1; D11S287E; PRAD1; U21B31	cyclin D1
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001082	MAPK7	BMK1; ERK4; ERK5; PRKM7	mitogen-activated protein kinase 7
TCMBANKGE001089	PARP1	ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1	poly(ADP-ribose) polymerase 1
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE001118	MMP9	CLG4B; GELB; MANDP2; MMP-9	matrix metallopeptidase 9
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001165	XIAP	API3; BIRC4; IAP-3; ILP1; MIHA; XLP2; hIAP-3; hIAP3	X-linked inhibitor of apoptosis
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001169	BCL2L1	BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52	BCL2 like 1
TCMBANKGE001201	MAPK3	ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK	mitogen-activated protein kinase 3
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE001203	MAPK1	ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK	mitogen-activated protein kinase 1
TCMBANKGE002300	MAPK4	ERK-4; ERK4; PRKM4; p63-MAPK; p63MAPK	mitogen-activated protein kinase 4
TCMBANKGE002480	MAPK11	P38B; P38BETA2; PRKM11; SAPK2; SAPK2B; p38-2; p38Beta	mitogen-activated protein kinase 11
TCMBANKGE006270	TRAF1	EBI6; MGC:10353	TNF receptor associated factor 1
TCMBANKGE009127	BCL2A1	ACC-1; ACC-2; ACC1; ACC2; BCL2L5; BFL1; GRS; HBPA1	BCL2 related protein A1
TCMBANKGE009756	MAPK6	ERK3; HsT17250; PRKM6; p97MAPK	mitogen-activated protein kinase 6
TCMBANKGE010738	SCD5	ACOD4; FADS4; HSCD5; SCD2; SCD4	stearoyl-CoA desaturase 5
TCMBANKGE012429	MAPK15	ERK7; ERK8	mitogen-activated protein kinase 15
TCMBANKGE012574	MAPK12	ERK-6; ERK3; ERK6; MAPK 12; P38GAMMA; PRKM12; SAPK-3; SAPK3	mitogen-activated protein kinase 12