Compound Summary

  Compound Information

TCMBANKIN000044

药名:	hypericin
别名:	4,5,7,4',5',7'-Hexahydroxy-2,2'-dimethylnaphthodianthrone; (component of) Hypericum spp (st. John's wort); Cyclosan; 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro [1,10,9,8-opqra]perylene-7,14-dione P-conformer; NSC 407313; Hypericin & Visible light; NCGC00162454-01; Cyclo werrol; NCI60_006799; VIMRxyn; InChI=1/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H; AIDS052002; Hypericum Extract; Cyclo-Werol; 56690_FLUKA; phenanthro[1,10,9,8-opqra]perylene-7,14-dione, 1,3,4,6,8,13-hexahydroxy-10,11-dimethyl-; HSCI1_000202; C07606; NCGC00163378-01; 4,5,7,4',5',7'-Hexahydroxy-2,2'-dimethyl-mesonapthtodianthron; NSC 622946; AIDS000117; AIDS-052002; NSC622946; Hypericum red; Hypericin from Hypericum perforatum; NCI60_003879; DRG-0113; EINECS 208-941-0; 548-04-9; 1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione; LMPK02000026; Phenanthro[1,10,9,8-opqra]perylene-7,14-dione,1,3,4,6,8,13-hexahydroxy-10,11-dimethyl-, stereoisomer; BiomolKI_000032; NSC407313; 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro(1,10,9,8-opqra)perylene-7,14-dione; BiomolKI2_000040; AIDS-000117; Hypericin
分子式:	C30H16O8
Smiles:	CC1=CC(=O)C2=C(C3=C(C=C(C4=C3C5=C2C1=C6C(=CC(=O)C7=C(C8=C(C=C(C4=C8C5=C67)O)O)O)C)O)O)O
成分:	HBIN029828
OB_score:	14.66493
CAS_id:	548-04-9
SymMap_id:	SMIT04377
TCMID_id:	10885
TCMSP_id:	MOL002067
PubChem_id:	3663

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000919	Hypericum wightianum	遍地锦			To clear heat and resolve toxin, arrest diarrhea./White mouth sore in children, infant pneumonia, stomatitis, mammary welling abscess, yellow-water sore, poisonous snake bites, diarrhea, enduring dysentery.
TCMBANKHE003799	Fructus Forsythiae	连翘			To remove toxic heat, to cause subsidence of sweeling,and to eliminate modulation./Influenza in early stage, common cold in early stage, wind-heat common cold, encephalitis, hepatitis, tuberculosis, warm disease, heat strangury with inhibited pain, welling abscess, welling abscess and flat abscess, toxin swelling, scrofula, goiter and tuberculosis, throat impediment.
TCMBANKHE004222	Hypericum curvisepalum	贯叶金丝桃
TCMBANKHE005677	Hypericum calycinum	大萼金丝桃
TCMBANKHE006060	Herba Hyperici Japonici	地耳草			1.To deprive dampness and relieve jaundice. 2. To clear away heat and toxic material. 3. To promote blood circulation and relieve edema./Damp-heat jaundice, diarrhea, dysentery, intestinal welling abscess, pulmonary welling abscess, swelling toxin of welling abscess and boil, nipple moth, mouth sore, red eyes with gall, poisonous snake bite, knocks and falls.
TCMBANKHE006755	Herba Hyperici japonici	田基黄;地耳草			1.To deprive dampness and relieve jaundice. 2. To clear away heat and toxic material. 3. To promote blood circulation and relieve edema./Damp-heat jaundice, diarrhea, dysentery, intestinal welling abscess, pulmonary welling abscess, swelling toxin of welling abscess and boil, nipple moth, mouth sore, red eyes with gall, poisonous snake bite, knocks and falls.
TCMBANKHE006447	Hypericum erectum	小连翘			To regulate menstruation and stanch bleeding, dissipate stasis and relieve pain, resolve toxin and disperse swelling./Blood ejection, hemoptysis, spontaneous external bleeding, hematochezia, flooding and spotting, bleeding due to external injury, menstrual disorder, postpartum galactostasis, knocks and falls, pain in joints due to rheumatalgia, swelling toxin of sore and boil, poisonous snake bite.
TCMBANKHE006886	Hypericum perforatum	贯叶连翘			To promote astriction and stanch bleeding, regulate menstruation and free milk, clear heat and resolve toxin, disinhibit damp./Hemoptysis, blood ejection, intestinal wind bleeding, flooding and spotting, bleeding due to external injury, menstrual disorder, galactostasis, jaundice, throat pain, red eyes with gall, urinary tract infection, mouth sore, nose sores, swelling toxin of welling abscess and boil, burns and scalds.
TCMBANKHE006980	Hypericum faberi	扬子小连翘
TCMBANKHE007572	Hypericum sampsonii	元宝草			To cool blood and stanch bleeding, clear heat and resolve toxin, quicken blood and regulate menstruation, dispel wind and free network vessels./Blood ejection, hemoptysis, spontaneous external bleeding, blood strangury, bleeding from wounds, enteritis, dysentery, mammary welling abscess, swollen welling abscess and toxin of clove sore, scalds, snake bite, menstrual disorder, menstrual pain, leukorrhea, knocks and falls, wind-damp impediment pain, pain in lumbus and leg, tinea capitis, mouth sore, eye screen.
TCMBANKHE008102/YEM-642	Herba Sedi sarmentosi|Sedum sarmentosum Bunge	垂盆草	垂盆草	云南民族药物志：第四卷	To remove damp-heat, and to counteract toxicity./1. Its amino acid protect the liver of rats and mice from CCl4 damage.2. Inhibiting the growth of Staphyloccus aureus, (a0 and (B) streptococcus and Shigella flexneri in vitro.	苗族/水族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000053	NFKB1	CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB	nuclear factor kappa B subunit 1
TCMBANKGE000376	CRTC3	TORC-3; TORC3	CREB regulated transcription coactivator 3
TCMBANKGE001098	NFKBIA	EDAID2; IKBA; MAD-3; NFKBI	NFKB inhibitor alpha
TCMBANKGE001184	RELA	CMCU; NFKB3; p65	RELA proto-oncogene, NF-kB subunit
TCMBANKGE001697	MMP1	CLG; CLGN	matrix metallopeptidase 1
TCMBANKGE013409	GSR	GR; GSRD; HEL-75; HEL-S-122m	glutathione-disulfide reductase