Compound Summary


  Compound Information

药名:

cepharanthine

别名:

AC1Q70ZF; NCGC00095194-03; NCGC00095194-01; Oxyacanthan,12'-dimethoxy-2,2'-dimethyl-6,7- [methylenebis(oxy)]-; 22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.216,19.13,10.121,25.04,8.014,39.031,35]nonatriaconta-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-dodecaene(non-preferred name); NCGC00095194-02; MCULE-9714795096; NSC-623442; CHEMBL1473842; NCGC00095194-04; 22,33-DIMETHOXY-13,28-DIMETHYL-2,5,7,20-TETRAOXA-13,28-DIAZAOCTACYCLO[25.6.2.2(1)?,(1)?.1(3),(1)?.1(2)(1),(2)?.0?,?.0(3)(1),(3)?.0(1)?,(3)?]NONATRIACONTA-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-DODECAENE; HMS3370G06; AC1L7HHO; 6-Methoxy-3,4'-(methylene(2-methyl-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1,7-diyl)oxy(2-methyl-6,7-(epoxymethanoxy)-1,2,3,4-tetrahydroisoquinoline-8,1-diyl)methylene)(1,1'-oxybisbenzene)

分子式:

C37H38N2O6

Smiles:

CN1CCC2=CC3=C(C4=C2C1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)CC7C8=CC(=C(C=C8CCN7C)OC)O4)OC)OCO3

成分:

HBIN020124

OB_score:

77.417653

CAS_id:

481-49-2

SymMap_id:

SMIT00671

TCMID_id:

3412

TCMSP_id:

MOL006973

PubChem_id:

10206


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE006371 白屈菜 Pain in sensory nerve endings, pain from ulcer in digestive tract, stomachache, abdominal pain, enteritis, dysentery, chronic bronchitis, pertussis, cough, jaundice, edema, ascites, scab and lichen with swelling of sores, snake or insect bites.
TCMBANKHE005795 Stephania sasakii 台湾千金藤 To settle pain, promote vomiting./Tuberculosis, bronchitis, pertussis, chronic sores, poisonous snake bite, malaria.
TCMBANKHE007928 白药子 Septicemia, acute hepatitis, bacillary dysentery, parotitis, neurodermatitis, swelling pain in throat, heat toxin swollen welling abscess, wind-damp impediment pain, abdominal pain and diarrhea, blood ejection, bleeding, spontaneous external bleeding, bleeding due to external injury.
TCMBANKHE005917/YNS-55/YEM-141/YEM-655 Stephania delavayi [Syn. Stephania epigaea ]|Stephania epigaea H.S.Lo 地不容|地不容(山乌龟) 地不容 |地不容 云南药材标准:第一册|云南民族药物志:第四卷 祛风除湿,清热解毒,止痛。用于胃痛,风湿痹痛,咽喉不利,痈肿疮毒|To rectify qi and relieve pain, dispel wind-damp, disperse swelling toxin./Qi stagnation and food accumulation, pain in stomach duct and abdomen, wind-damp impediment pain, swelling toxin of welling abscess and sore, poisonous snake bite. 傣族/基诺族/拉祜族/佤族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000048 Neoplasms group Neoplasms 28923401
TCMBANKDI000088 Lung Neoplasms group Neoplasms; Respiratory Tract Diseases 29024815
TCMBANKDI011552 Kidney Diseases group Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 21628669
TCMBANKDI012932 HIV Infections group Infections; Immune System Diseases 21628669

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE003300 EIF6 CAB; EIF3A; ITGB4BP; b(2)gcn; eIF-6; p27(BBP); p27BBP eukaryotic translation initiation factor 6
TCMBANKGE010213 HERC5 CEB1; CEBP1 HECT and RLD domain containing E3 ubiquitin protein ligase 5