Compound Summary


  Compound Information

药名:

stachydrine

别名:

dimethylproline; (-)-Stachydrine; (2S)-2-carboxy-1,1-dimethylpyrrolidinium; proline betaine; (S)-2-carboxy-1,1-dimethylpyrrolidinium; 104622-EP2301932A1; AJ-38211; (2S)-1,1-DIMETHYL-1??-PYRROLIDINE-2-CARBOXYLIC ACID; Prestwick2_000622; SR-05000002246; SCHEMBL578113; (2S)-1,1-dimethylpyrrolidin-1-ium-2-carboxylic acid; BPBio1_000644; 1sw1; 2b4m; Prestwick1_000622; ZINC2528042; SPBio_002803; stachy-drine; BSPBio_000584; SC-20792; AC1L9LTA; CHEBI:44813; Prestwick0_000622; N,N-dimethyl-L-prolinium; 1,1-DIMETHYL-PROLINIUM; SR-05000002246-2; Prestwick3_000622

分子式:

C7H13NO2

Smiles:

C[N+]1(CCCC1C(=O)[O-])C

成分:

HBIN044690

OB_score:

0.268288

CAS_id:

471-87-4

SymMap_id:

SMIT00046

TCMID_id:

20238;34503

TCMSP_id:

MOL000447

PubChem_id:

115244


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003373 Exocarpium Citri grandis 化橘红 To dispel cold, eliminate damp and phlegm, and arrest emesis or nausea./Treatment of cough, itching of the throat and profuse expectoration in colds, nausea, vomiting and epigastric distension caused by improper diet or excessive drinking.
TCMBANKHE003426 Fructus Leonuri 茺蔚子 To activate blood circulation and regulate menstruation, to subdue hyperactivity of the liver, and to clear the eye of opacity./Treatment of menstrual disorders, amenorrhea, hysmenorrhea, inflammation of the eye with formation of corneal opacity, dizziness and headache.
TCMBANKHE003718 Flos Chrysanthemi 菊花 To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.
TCMBANKHE003919 Medicago sativa 苜蓿 To clear heat and cool blood, disinhibit damp and abate jaundice./Febrile diseases with vexation and fullness, jaundice, enteritis, dysentery, edema, urethral stone, hematochezia from hemorrhoids.
TCMBANKHE004298 Calyx Kaki 柿蒂 To check the upward flow of the stomach qi./Hiccough.
TCMBANKHE004374 Urtica cannabina 荨麻 To dispel wind and free network vessels, calm liver and settle fright, disperse accumulation and free stool, resolve toxin./Wind-damp impediment pain, postpartum wind tetany, infant fright wind, sequel of poliomyelitis, hypertension, indigestion, fecal stoppage, urticaria, knocks and falls, snake or insect bites.
TCMBANKHE006367 Glycyrrhiza squamulosa 圆果甘草 See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis .
TCMBANKHE004699 fructus hippophae 沙棘
TCMBANKHE005071 Herba Visci 槲寄生 To relieve rheumatic conditions, to replenish the liver and the kidney, to strengthen the tendons and the bones, and to prevent abortion./Hypertension, cerebral and cardiovascular diseases, wind-damp impediment pain, limp aching lumbus and knees, stirring fetus in pregnancy.
TCMBANKHE005100 Sabia schumanniana 四川清风藤 To dispel wind and quicken blood, relieve cough and transform phlegm./Wind-damp impediment pain, knocks and falls, lumbago, chronic cough and asthma.
TCMBANKHE007973 Herba Artemisiae Scopariae 茵陈 To remove damp-heat and relieve jaundice./1. Its decoction or its volatile oil, and active components such as chlorogenic acid, caffeic acid and hydroxyacetophenone are chologogues.2. Protecting the liver of experimental animals from the damage of CCl4.3. Decreasing the level of blood lipids and alleviating artherosclerosis and lipidosis in rabbits.4. Increasing the coronary flow of rabbits in vitro.5. Its volatile oil inhibits the growth of Shigella dysenteriae, Hemolytic streptococcus and various dermatomyces in vitro.6. Anticoagulative.
TCMBANKHE005422 Herba Leonuri,Leonurus cardiaca 益母草,欧益母草,胃益母草 1. To promote blood circulation to remove blood stasis, regulate menstruation and relieve metrorrhagia. 2. To promote diuresis and relieve edema. 3. To clear heat and toxic materials. 4. Lower blood pressure./Menstrual disorder, dysmenorrhea, amenorrhea, postpartum bleeding, persistent flow of lochia, edema, scant urine with edema, acute nephritis with edema.
TCMBANKHE005793 Flos Chrysanthemi 菊花 To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.
TCMBANKHE005874 玳玳花 Oppression in chest due to glomus, distending pain in stomach duct and abdomen, vomiting, reduced food intake.
TCMBANKHE008128 Capparis spinosa 老鼠瓜 To dispel wind, dissipate cold, eliminate damp./Acute rheumatic arthritis, chronic rheumatic arthritis.
TCMBANKHE007509 Stachys tuberifera 块茎水苏
TCMBANKHE008315 Cortex erythrie 海桐皮 1. To dispel wind and dampness; 2. To clear the meridians/Wind-damp impediment, pain in lumbus and knees, scab sore, lichen, eczema.
TCMBANKHE008586 Leonurus sibiricus 细叶益母草 See Leonurus heterophyllus./See Leonurus heterophyllus.
TCMBANKHE004643/YEM-590/XU-716 Folium Mori|Morus alba L.|Morus alba 桑叶|桑 桑叶 云南民族药物志:第三卷|云南省昭通市盐津县 To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision. 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE007787/YEM-776 Cudrania tricuspidata|Cudrania tricuspidata(Carr.)Bur.ex Lavallée 柘树 痄腮树 云南民族药物志:第四卷 To enrich and nourish blood vessel, harmonize spleen and stomach./Vacuity detriment, flooding, malaria. 水族/佤族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI018012 Ureteral obstruction phenotype Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 24840537

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1