Compound Summary

  Compound Information

TCMBANKIN000062

药名:	Fraxinellone
别名:	28808-62-0; 1(3H)-Isobenzofuranone, 3-(3-furanyl)-3a,4,5,6-tetrahydro-3a,7-dimethyl-, (3R-cis)- (9CI); Phthalide, 3-(3-furyl)-3a,4,5,6-tetrahydro-3a,7-dimethyl-; NCI60_012928; NSC638730; fraxinellone; (3R,3aR)-3-furan-3-yl-3a,7-dimethyl-3,4,5,6-tetrahydro-2-benzofuran-1-one; fraxinellone ; (3R,3aR)-3-(3-furyl)-3a,7-dimethyl-3,4,5,6-tetrahydroisobenzofuran-1-one; ZINC00265490
分子式:	C14H16O3
Smiles:	CC1=C2C(=O)OC(C2(CCC1)C)C3=COC=C3
成分:	HBIN026738
OB_score:	35.955059
CAS_id:	28808-62-0
SymMap_id:	SMIT07907
TCMID_id:	7944
TCMSP_id:	MOL006258
PubChem_id:	124039

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004113	Fraxinus ornus	花白蜡树
TCMBANKHE004443	Fraxinus potamophila	土耳其斯坦白腊树
TCMBANKHE004713	Chimonanthus fragrans [Syn. Chimonanthus praecox]	腊梅花			To clear heat and resolve summerheat, rectify qi and open depression./Summerheat-heat vexation and thirst, dizziness, oppression in chest due to glomus, globus hystericus, swelling pain in throat, pertussis, child measles, burns and scalds.
TCMBANKHE005027		苦楝皮			Ascariasis, oxyuria disease, abdominal pain due to worm accumulation, scab and lichen with itching.
TCMBANKHE005444		白鲜皮			To clear heat and dry damp, dispel wind and relieve itch, resolve toxin./1. Inhibiting the growth of pathogenic fungi. 2. Its infusion lowers vaccine-induced fever in rabbits. 3. Dictamnine, one of its active components, increase the myocardial tone of frogs. Dermatitis, psoriasis, icterohepatitis, damp-heat sore and papules, profuse pus, yellow-water sore, damp ulceration on skin, itchy skin, damp-heat jaundice, damp-heat impediment.
TCMBANKHE005660	Aesculus hippocastanum	欧洲七叶树			See Aesculus wilsonii./See Aesculus wilsonii.
TCMBANKHE008639	Fraxinus bungeana	小叶梣			See Fraxinus rhynchophylla ./See Fraxinus rhynchophylla .
TCMBANKHE006960	Fraxinus szaboana [Syn. Fraxinus chinensis var. acuminata]	尖叶梣			See Fraxinus rhynchophylla ./See Fraxinus rhynchophylla .
TCMBANKHE008457	Fraxinus stylosa	柳叶岑			See Fraxinus rhynchophylla ./See Fraxinus rhynchophylla .

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000048

Neoplasms

group

Neoplasms

30103001

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000221	GRIA2	GLUR2; GLURB; GluA2; GluR-K2; HBGR2; gluR-2; gluR-B	glutamate ionotropic receptor AMPA type subunit 2
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000633	ADRB2	ADRB2R; ADRBR; B2AR; BAR; BETA2AR	adrenoceptor beta 2
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE000965	CHRNA7	CHRNA7-2; NACHRA7	cholinergic receptor nicotinic alpha 7 subunit
TCMBANKGE001506	ADRA1B	ADRA1; ALPHA1BAR	adrenoceptor alpha 1B
TCMBANKGE001943	ADRA1D	ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2	adrenoceptor alpha 1D
TCMBANKGE003157	CHRM2	HM2	cholinergic receptor muscarinic 2
TCMBANKGE005535	CHRM1	HM1; M1; M1R	cholinergic receptor muscarinic 1
TCMBANKGE006943	CHRM3	EGBRS; HM3; PBS	cholinergic receptor muscarinic 3
TCMBANKGE009758	PDE3A	CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB	phosphodiesterase 3A
TCMBANKGE011923	CHRM4	HM4; M4R	cholinergic receptor muscarinic 4
TCMBANKGE012155	SLC6A3	DAT; DAT1; PKDYS; PKDYS1	solute carrier family 6 member 3
TCMBANKGE014050	GABRA1	ECA4; EIEE19; EJM; EJM5	gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014423	ADRA1A	ADRA1C; ADRA1L1; ALPHA1AAR	adrenoceptor alpha 1A