Compound Summary

  Compound Information

TCMBANKIN000063

药名:	ecdysone
别名:	Hydroxyecdysone; UNII-779A7KPL0Y; CHEMBL224128; 779A7KPL0Y; (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; MolPort-002-507-287; A,22,25-Hexahydroxy-7-cholesten-6-one; LMST01010209; .beta-Ecdysterone; henanthren-6-one; MCULE-9660893096; 20-OH ecdysone; MLS001164644; 20E; BG00831842; (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(1R,2R)-1,2,5-trihydroxy-1,5-dimethyl-hexyl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; CTK8E9736; AC1NUSFS; beta-ECDYSTERONE; AB3000033; 20-HYDROXYECDYSONE; Isoinokosterone; AKOS004120029; (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-6H-cyclopenta[a]p; A,20; (2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one; DTXSID5040388; Crustecdysone; Crustecdyson; Ecdysterone; N1350; MFCD00036740; Insect moulting hormone; SCHEMBL22086; V0682; (2S,3R,5R,9R,10R,13R,14S,17S)-10,13-dimethyl-17-[(2R,3R)-6-methyl-2,3,6-tris(oxidanyl)heptan-2-yl]-2,3,14-tris(oxidanyl)-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; 20-Hydroxyecdysone, >=93% (HPLC), powder; NKDFYOWSKOHCCO-YPVLXUMRSA-N; 20-E; (22R)-2beta,3beta,14alpha,20,22,25-hexahydroxy-5beta-cholest-7-en-6-one; 5289-74-7; CH0034; 137704-EP2374792A1; A829299; beta-Ecdysone; 20-Hydroxyecdyson; BB_NC-1013; BG01762865; Q-201054; A,3; Viticosterone; MLS002207226; Ecdysteron; A,22,25-Hexahydroxy-7-cholesten-6-one;Ecdysterone;Insect moulting hormone;Polypodine A; Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2b,3b,5b,22R)-; A,14; (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-6H-cyclopenta[a]phenanthren-6-one; AC-19603; C27H44O7; 2beta,3beta,14alpha,20beta,22,25-Hexahydroxy-7-cholesten-6-one; 20-Hydroxy-a-ecdysone; TR-018728; THE-7; Polypodine A; b-Ecdysone; BDBM50326777; (2Beta,3beta,5beta)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one; 2beta,3beta,14alpha,20,22R,25-hexahydroxy-5beta-cholest-7-en-6-one; ZINC238809241; 20-Hydroxyecdysone;2; HMS2230L09; Commisterone; 2,3,14-Trihydroxy-10,13-dimethyl-17-(1,2,5-trihydroxy-1,5-dimethyl-hexyl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-6-one; s2417; SMR000539832; 289E747; CHEBI:16587
分子式:	C27H44O6
Smiles:	CC(C1CCC2(C1(CCC3C2=CC(=O)C4C3(CC(C(C4)O)O)C)C)O)C(CCC(C)(C)O)O
成分:	HBIN024784
SymMap_id:	SMIT01390
TCMID_id:	6677
PubChem_id:	19212

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003647	Polypodium vulgare				To clear heat, resolve toxin and disinhibit damp./Damp-heat strangury pain, wind-damp-heat impediment, swollen welling abscess, sore and boil, wind papule itching, knocks and falls.
TCMBANKHE003757	Matteuccia struthiopteris	小叶贯众			To clear heat and resolve toxin, kill worms, stanch bleeding./Febrile diseases macular eruption, parotitis, damp-heat sore toxin, abdominal pain due to ascariasis, oxyuria disease, red dysentery and bloody stool, hematuria, blood ejection, spontaneous external bleeding, flooding and spotting [=metrorrhagia and metrostaxis].
TCMBANKHE003911	Folium Sene	番泻叶			To purge feces downward/Heat bind and accumulation, constipation w ith abdominal pain, edema distention fullness.
TCMBANKHE004952	Lemmaphyllum microphyllum	螺厣草			To clear lung and relieve cough, cool blood and stanch bleeding, clear heat and resolve toxin./Lung heat cough, pulmonary welling abscess, hemoptysis, blood ejection, spontaneous external bleeding, hematuria, hematochezia, flooding and spotting, swelling pain in throat, parotitis, dysentery, scrofula, swelling toxin of welling abscess and sore, damp itchy skin, wind-fire toothache, wind-damp bone pain.
TCMBANKHE005177	Pteridium aquilinum	欧洲蕨
TCMBANKHE007439	Bombyx mori	白僵蚕			To dispel wind and resolve tetany, transform phlegm and dissipate binds, resolve toxin and disinhibit throat./Epilepsy, fright wind and convulsion, swelling pain in throat, acute infection of upper respiratory tract, epidemic parotitis, diabetes mellitus, temporomandibular lymphrnoditis, facial paralysis, itchy skin.
TCMBANKHE005577	Lychnis fulgens	大花剪秋罗			To clear heat and disinhibit urine, fortify spleen, quiet spirit./Inhibited urination, child gan accumulation, night sweating, headache, insomnia.
TCMBANKHE007643	Vinca minor	蔓长春花
TCMBANKHE005747	Blechnum minus	小乌毛蕨
TCMBANKHE008355	Polypodium niponicum	水龙骨			To clear heat and disinhibit damp, quicken blood and free network vessels./Opacity of urine, diarrhea, strangury, wind-damp impediment pain, knocks and falls.
TCMBANKHE008310	Cortex Eucommiae	杜仲			To tonify the liver and the kidney, to strengthen the tendons and bones, and to prevent miscarrige./Hypertension, kidney vacuity lumbago, weakness in sinews and bones, stirring fetus in pregnancy.
TCMBANKHE007018	Bombyx mori	原蚕蛾			To supplement kidney and invigorate yang , rough essence, stanch bleeding, resolve toxin and disperse swelling./Impotence and emission, white turbidity, blood strangury, incised wound and bleeding, swelling pain in throat, mouth and tongue sores, swelling toxin of welling abscess and sore, frostbite, snake bite.
TCMBANKHE004110/YEM-208	Rhizoma Dryopteris crassirhizomae|Osmunda japonica Thunb.	贯众|紫箕	紫箕贯众	云南民族药物志：第一卷	1. To clear heat and toxic material. For preventing and treating pestilence and seasonal febrile diseases, such as influenza, epidemic cerebrospinal meningitis, mumps, measles, etc., also for viral pneumonia. 2. To cool the blood nad stop bleeding. For profuse uterine bleeding due to blood-heat, hematemesis, epistaxis, hemafacia, eruptive diseases, etc.3. To kill parasites/1.Antivirotic and bacteriostatic. 2. Parasiticidal effect on hookworm, roundworm and whipworm, etc. in human, and its component filmarone, on tapeworm. 3. Its decoction shortens the blood clotting time in rabbits. 4. Its extract exerts an abortive effect.	傈僳族
TCMBANKHE000209/YEM-208	Osmunda japonica|Osmunda japonica Thunb.	紫箕	紫箕贯众	云南民族药物志：第一卷	To clear heat and resolve toxin, dispel stasis and stanch bleeding, kill worms./Influenza, epidemic encephalitis, parotitis, swelling toxin of welling abscess and sore, measles papules, varicella, dysentery, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, vaginal discharge, intestinal parasitic disease.	傈僳族
TCMBANKHE008167/YEM-39/XU-672	Cortex Eucommiae|Eucommia ulmoides Oliv.|Eucommia ulmoides	杜仲	杜仲	云南民族药物志：第一卷|贵州省岑巩县平庄镇师兆村	To tonify the liver and the kidney, to strengthen the tendons and bones, and to prevent miscarrige./Hypertension, kidney vacuity lumbago, weakness in sinews and bones, stirring fetus in pregnancy.	阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000048	Neoplasms	group	Neoplasms	30120247
TCMBANKDI003353	Carcinogenesis	phenotype	Pathological Conditions, Signs and Symptoms; Neoplasms	30120247

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000246	FOXO1	FKH1; FKHR; FOXO1A	forkhead box O1
TCMBANKGE000295	FOXO3	AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A	forkhead box O3
TCMBANKGE000669	LAS1L	Las1; Las1-like; WTS; dJ475B7.2	LAS1 like ribosome biogenesis factor
TCMBANKGE000670	HDAC8	CDA07; CDLS5; HD8; HDACL1; KDAC8; MRXS6; RPD3; WTS	histone deacetylase 8
TCMBANKGE000671	SLCO1A2	OATP; OATP-A; OATP1A2; SLC21A3	solute carrier organic anion transporter family member 1A2
TCMBANKGE001059	LATS1	WARTS; wts	large tumor suppressor kinase 1
TCMBANKGE001060	YAP1	COB1; YAP; YAP2; YAP65; YKI	Yes1 associated transcriptional regulator
TCMBANKGE001083	MAP3K5	ASK1; MAPKKK5; MEKK5	mitogen-activated protein kinase kinase kinase 5
TCMBANKGE001085	MAPK8	JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c	mitogen-activated protein kinase 8