Compound Summary


  Compound Information

药名:

diosgenin

别名:

AKOS025402315; MolPort-028-744-580; (25R)-5-Spirosten-3beta-ol; 3beta-Hydroxy-5-spirostene; nitogenin; NSC 226132; Spirost-5-en-3-ol, (3beta,25S)-; diosgenin ; AC-8024; 512-04-9; 22-epi-Yamogenin; C08898; D1634_SIGMA

分子式:

C27H42O3

Smiles:

CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)O)C)C)C)OC1

成分:

HBIN024164

OB_score:

80.877925

CAS_id:

512-04-9

SymMap_id:

SMIT00060

TCMID_id:

6439

TCMSP_id:

MOL000546

PubChem_id:

137704703


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000074 Dioscorea hirsuta 粗毛栓菌
TCMBANKHE000698 Radix Asparagi 天冬 To replenish yin, promote fluid secretion and moisten the lung./1. Asparamide is an expectorant, antitussive and antiasthmatic.2. Inhibiting the cell growth of acute lymphocytic, acute monocytic and chronic granulocytic leukemias in vitro.
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE001065 Dioscorea futschauensis To dispel wind-damp, disinhibit damp and turbidity, disperse swelling toxin./Wind-damp impediment pain, strangury with pain, white turbidity, leukorrhea, damp sore.
TCMBANKHE001256 Radix Schefflerae Arboricolae 七叶莲 1. Treatment of rheumatism, trauma, headache, and other pains. Recently, also used for abdominal and biliary colics, and trigeminal neuralgia. 2. Treatment of bronchial asthma and asthmatic bronchitis./1. Analgeic. 2. Sedative. 3. Antispasmodic
TCMBANKHE001777 Rhizoma Dioscoreae Nipponicae 穿山龙 1. To promote blood circulation and dredge the channels. 2. To expel wind and dampness. 3. To eliminate phlegm, and relieve cough and dyspnea. 4. To clear toxic materials and relieve swelling./1. Its saponins are antitussives and expectorants.2. Its decoction can relax histamine- or acetylcholine-induced bronchial spasm in guinea-pigs.3. Decreasing cholesterol level, slowing heart rate and increasing coronary flow.4. Anti-allergic.
TCMBANKHE002006 宽叶重楼
TCMBANKHE002149 楮实子
TCMBANKHE002499 Rhizoma Ahemones Daddeae 两头尖 To relieve rheumatic conditions, and to cure carbuncle./Treatment of rheumatoid arthritis with muscular contracture and joint pain, carbuncle with ulceration.
TCMBANKHE002964 Paris fargesii 球药隔重楼
TCMBANKHE004898 Smilax menispermoidea 防己叶菝葜 See Smilax glabra ./See Smilax glabra .
TCMBANKHE003028 粉萆薢 Treatment of chyluria, turbid urine mixed with whitish substance or whitish discharge from urethra, excessive leukorrhea, rheumatic arthralgia with limitation of motion and pain in the loins and knees.
TCMBANKHE003407 Microphale Pilosipe 鬼毛针
TCMBANKHE003600 Gummi Elasticum 天然橡胶
TCMBANKHE003739 龙葵 Clove sore, swollen welling abscess, erysipelas, sprain from knocks and falls, mastitis, cervicitis, chronic bronchitis, chronic trachitis, acute nephritis, dysentery, infection of skin, leukorrhea, scant urine in children.
TCMBANKHE003993 南蛇藤果 Palpitation and insomnia, amnesia and heavy dreams, toothache, pain in sinews and bones, numbness in lumbus and leg, painful wound from knocks and falls.
TCMBANKHE005809 Dioscorea parviflora 小花盾叶薯蓣 To clear heat and resolve toxin, quicken blood and disperse swelling./Swelling toxin of welling abscess and boil, soft tissue sprain, bee sting, insect bites.
TCMBANKHE004172 Radix Bupleuri 柴胡 To relieve fever, to soothe the liver, and to cure drooping and ptosis./Common cold, influenza, malaria, acute pancreatitis, pleuritis, neuritis, gastritis, acute cholecystitis, hepatitis, fever due to external contraction, keratitis, cold-heat in turn, liver depression and rib-side pain, mammary distention, dizziness and headache, menstrual disorder, prolapse of rectum due to qi vacuity fall, prolapse of uterus, gastroptosis.
TCMBANKHE004179 Dioscorea hispida 白薯莨 To clear heat and resolve toxin, disperse swelling./Swelling toxin of welling abscess and flat abscess, syphilis, chancre, painful swelling from knocks and falls.
TCMBANKHE004287 Radix Achyranthis bidentatae 牛膝 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat.
TCMBANKHE004439 Rhizoma Smilacis Glabrae 土茯苓 To remove damp, to counteract toxicity, and to improve the mobility of joints./Damp-heat with strangury turbidity, vaginal discharge, swollen welling abscess, scrofula, scab and lichen, syphilis, mercurial poisoning.
TCMBANKHE004539 Fructus Kochiae 地肤子 To remove damp-heat, to dispel zvind, and to relieve itching./Inhibiting the growth of various dermatomyces in vitro.
TCMBANKHE004685 Dioscorea althaeoides 蜀葵叶薯蓣 To course wind and dispel damp, fortify spleen and disperse food, quicken blood and disperse swelling./common cold with headache, wind-damp impediment pain, food accumulation distention and fullness, indigestion, knocks and falls.
TCMBANKHE007077 Dioscorea nipponica ssp. rosthornii 柴黄姜 See Dioscorea nipponica./See Dioscorea nipponica.
TCMBANKHE005363 Semen Plantaginis 车前子 To remove heat, to cause diuresis and eliminate damp, to relieve dysuria, to clear the eye, and to promote expectoration./1. Diuretic. 2. Expectorant and antitussive.
TCMBANKHE007411 Dioscorea panthaica 黄山药 To rectify qi and relieve pain, resolve toxin and disperse swelling./Qi stagnation stomachache, vomiting diarrhea with abdominal pain, taxation detriment due to knocks and falls, toxin swelling of sores, poisonous snake bite.
TCMBANKHE005949 Rhizoma Polygoti 黄精 To reinforce qi and nourish yin, to invigorate the function of the spleen, to moisten the lung, and to benefit the kidney./Yin vacuity taxation cough, lung heat dry cough, fatigue hypodynamia due to spleen vacuity, reduced food intake with dry mouth, diabetes mellitus, limp aching lumbus and knees due to kidney yin vacuity, impotence and emission, tinnitus and dim vision, premature graying in beard and hair, vacuity and marked emaciation, wind lai lichen.
TCMBANKHE006128 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE006158 Dioscorea zingiberensis 盾叶薯蓣 To clear lung and relieve cough, disinhibit damp and free strangury, free network vessels and relieve pain, resolve toxin and disperse swelling./Lung heat cough, damp-heat strangury pain, wind-damp lumbago, swollen welling abscess and malign sore, sprain from knocks and falls, bee sting, insect bites.
TCMBANKHE006165 Rhizoma Dioscoreae bulbiferae 黄药子 To remove phlegm, disperse the lumps, detoxify and relieve swelling. /Goiter and tuberculosis, throat impediment, swelling toxin of welling abscess and sore, poisonous snake bite, carcinoma, blood ejection, spontaneous external bleeding, hemoptysis, pertussis, lung heat cough.
TCMBANKHE006919 flos farfarae 款冬花 To relieve cough and resolve phlegm to nourish the lung to keep the adverse qi downward./Cough, cough and asthma with abundant phlegm, consumption cough and hemoptysis, chronic bronchitis, infection of upper respiratory tract, tuberculosis.
TCMBANKHE008332 绵萆薢 Strangury with white turbidity, excessive leukorrhea, damp-heat sore toxin, impediment pain in lumbus and knees.
TCMBANKHE008775 Rhizoma Dioscoreae 山药 To replenish the spleen and stomach, to promote fluid secretion and benefit the lung, and to strengthen the kidney and restrain seminal discharge.Rhizoma Dioscoreae (stir-fried with bran) To replenish the spleen and promote the stomach function./Reduced food intake due to spleen vacuity, incessant chronic diarrhea, cough and asthma due to lung vacuity, kidney vacuity and emission, vaginal discharge, frequent urination, vacuity heat and diabetes mellitus.
TCMBANKHE006488 Dioscorea nipponica ssp. rosthornii 柴黄姜 See Dioscorea nipponica./See Dioscorea nipponica.
TCMBANKHE006580 Calycis Melo 瓜蒂 Vomiting promotion/Wind stroke, epilepsy, throat impediment, indigestion of overnight food, distending pain in stomach duct, damp-heat jaundice, chronic hepatitis, cirrhosis.
TCMBANKHE008402 Dioscorea gracillima 纤细薯蓣 See Dioscorea hypoglauca./See Dioscorea hypoglauca.
TCMBANKHE009154 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE007606 菝葜 Wind-damp impediment pain, strangury-turbidity, vaginal discharge, dysentery, diarrhea, swelling toxin of welling abscess and sore, intractable lichen, burns and scalds.
TCMBANKHE007854 Dioscorea nipponica 穿龙薯蓣 To dispel wind and eliminate damp, quicken blood and relieve pain, relieve cough and dispel phlegm./Pain in joints, rheumatic endocarditis, sciatica, chronic bronchitis, chronic trachitis, wind-cold-damp impediment, indigestion, taxation detriment and sprain, malaria, swollen welling abscess.
TCMBANKHE008687 Rhizoma Anemarrhee 知母 To remove heat and quench fire, and to promote the production of body fluid and relieve dryness syndromes./Diabetes mellitus, warm heat disease, ardent fever with vexation and thirst, cough and asthma, dry cough, constipation, steaming bone tidal fever, vacuity vexation and insomnia, strangury-turbidity.
TCMBANKHE007625 Radix Solani melongee 茄根
TCMBANKHE008611 Dracaena draco 龙血树
TCMBANKHE006355/YNS-121 Reineckea carnea|Reineckea carnea(Andr.)Kunth 吉祥草 吉祥草 云南药材标准:第一册 清肺止咳,凉血解毒。用于肺热咳嗽,咯血,咽喉肿痛,目赤翳障,痈肿疮毒|To clear lung and relieve cough, cool blood and stanch bleeding, resolve toxin and disinhibit throat./Lung heat cough, hemoptysis, blood ejection, spontaneous external bleeding, hematochezia, swelling pain in throat, red eyes and eye screen, swollen welling abscess, sore and boil.
TCMBANKHE008911/YEM-126 Radix Achyranthis bidentatae|Achyranthes bidentata Blume 牛膝;怀牛膝|牛膝 牛膝 云南民族药物志:第一卷 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward.Treament of soreness of the lumbar and knee joints with weakness inthe legs, amenorrhea with mass formation in the abdomen, dizziness due to hyperactivity of the liver./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/彝族
TCMBANKHE003953/YEM-152 Asparagus cochinchinensis [Syn. Asparagus lucidus ]|Asparagus cochinchinensis (Lour.) Merr 天门冬 天冬 云南民族药物志:第一卷 To enrich yin and moisten dryness, clear lung and downbear fire./Yin vacuity fever, cough with blood ejection, lung wilting, pulmonary welling abscess, swelling pain in throat, diabetes mellitus, constipation. 傣族/哈尼族/基诺族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE005294/YEM-392 Ophiopogon japonicus|Liriope spicata(Thunb.)Lour. 麦冬|山麦冬 土麦冬 云南民族药物志:第二卷 To nourish yin and engender liquid, moisten lung and clear heart./Angina pectoris, dry cough due to lung dryness, vacuity consumption with cough, fluid damage and thirst, insomnia and vexation, diabetes mellitus due to internal heat, intestinal dry and constipation, diphtheria. 德昂族/水族/彝族
TCMBANKHE004548/YEM-392 Radix Liriopes|Liriope spicata(Thunb.)Lour. 山麦冬 土麦冬 云南民族药物志:第二卷 Treatment of dry cough caused by lung yin deficiency, cough caused by consumptive diseases, fluid deficiency and thirst, dysphoria and insomnia, constipation due to fluid deficiency of intestine./Treatment of dry cough caused by lung yin deficiency, cough caused by consumptive diseases, fluid deficiency and thirst, dysphoria and insomnia, constipation due to fluid deficiency of intestine. 德昂族/水族/彝族
TCMBANKHE007349/YEM-562 Dioscorea hypoglauca [Syn. Dioscorea collettii var. hypoglauca]|Dioscorea collettii Hook.f. 萆薢|叉蕊薯蓣 叉蕊薯蓣 云南民族药物志:第三卷 To disinhibit damp and turbidity, dispel wind-damp./Unctuous strangury, white turbidity, vaginal discharge, sores, wind-damp impediment pain. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE003914/YEM-562 Dioscorea collettii|Dioscorea collettii Hook.f. 叉蕊薯蓣 叉蕊薯蓣 云南民族药物志:第三卷 To dispel wind and disinhibit damp, free network vessels and relieve pain, clear heat and resolve toxin./Wind-damp impediment pain, hypertonicity and numbness, qi stagnation stomachache, damp-heat jaundice, white turbidity, strangury with pain, leukorrhea, knocks and falls, damp sore with swelling toxin, wind papules, eczema, poisonous snake bite. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE006634/YNS-20/YEM-636 Costus speciosus|Costus speciosus (Koen.) Smith|Costus speciosus(Koen.)Smith 樟柳头|闭鞘姜 闭鞘姜 云南药材标准:第五册|云南民族药物志:第四卷 除风解毒,利咽化痰,活血止痛,利水消肿,用于咽喉肿痛,咳喘痰多,痄腮,耳道溢脓,风湿痹痛,水肿,小便热涩疼痛,胆汁病(黄疸病,白疸病,黑疸病)|To move water and disperse swelling./Ascites, white turbidity, swollen welling abscess, malign sore. 阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/佤族/瑶族/壮族
TCMBANKHE005944/YEM-597/YEM-808 Paris polyphylla|Paris polyphylla Smith var.chinensis(Franch.)Hara 蚤休|七叶一枝花 华重楼 云南民族药物志:第四卷 To clear heat and resolve toxin, disperse swelling and relieve pain, cool liver and settle fright./Swelling toxin of welling abscess and sore, throat impediment, mammary welling abscess, snake or insect bites, painful wound from knocks and falls, liver heat and convulsion. 阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/瑶族/彝族
TCMBANKHE005834/YEM-597/YEM-808 Paris polyphylla var. yunnanensis|Paris polyphylla Smith var.chinensis(Franch.)Hara 云南重楼|七叶一枝花 华重楼 云南民族药物志:第四卷 See Paris polyphylla ./See Paris polyphylla . 阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/瑶族/彝族
TCMBANKHE002605/YEM-597/YEM-808 Rhizoma Paridis|Paris polyphylla Smith var.chinensis(Franch.)Hara 重楼|七叶一枝花 华重楼 云南民族药物志:第四卷 Treatment of boils, carbuncies, sore throat, venomous snake bite, traumatic pain, convulsions./1. Virustatic, esp. on Asia influenza A virus, and bacteriostatic. 2. Antitussive and antiasthmatic. 3. An active component, pariphyllin, exerts a sedative effect on mice and in synergistic with pentobarbital sodium. 4. Pariphyllin inhibits uterocervical carcinoma14 in mice. 阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/瑶族/彝族
TCMBANKHE001584/YEM-597/YEM-808 Paris polyphylla var. stenophylla|Paris polyphylla Smith var.chinensis(Franch.)Hara 狭叶重楼|七叶一枝花 华重楼 云南民族药物志:第四卷 See Paris polyphylla./See Paris polyphylla. 阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/瑶族/彝族
TCMBANKHE002852/YEM-597/YEM-808 Paris polyphylla var. pseudothibetica|Paris polyphylla Smith var.chinensis(Franch.)Hara 长药隔重楼|七叶一枝花 华重楼 云南民族药物志:第四卷 See Paris polyphylla ./See Paris polyphylla . 阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/瑶族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000007 melanoma disease Neoplasms 30305604

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000672 RPL17-C18orf32 PD-1; RPL17 RPL17-C18orf32 readthrough
TCMBANKGE000673 RPL17 L17; PD-1; RPL23 ribosomal protein L17
TCMBANKGE000674 PDCD1 CD279; PD-1; PD1; SLEB2; hPD-1; hPD-l; hSLE1 programmed cell death 1
TCMBANKGE001014 TNFRSF10B CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9 TNF receptor superfamily member 10b
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001201 MAPK3 ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK mitogen-activated protein kinase 3
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001203 MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK mitogen-activated protein kinase 1