Compound Summary


  Compound Information

药名:

ellipticine

别名:

ZINC00120296; 5-23-09-00417 (Beilstein Handbook Reference); 6H-Pyrido[4,3-b]carbazole, 5,11-dimethyl-; E3380_SIGMA; 5,11-dimethyl-6H-pyrido[4,3-b]carbazol-2-ium; K00071; EU-0100531; EINECS 208-264-0; BPBio1_000604; SMR000058370; C09154; BSPBio_000548; Lopac0_000531; NCGC00015411-02; AIDS-001996; Prestwick_194; NCI60_040685; Probes2_000130; Prestwick1_000614; MLS000028487; 5,11-Dimethyl-6H-pyrido[4,3-b]carbazole; Prestwick2_000614; 519-23-3; Lopac-E-3380; Prestwick3_000614; NSC71795; CP 5; SPBio_002767; WLN: T D6 B656 FN LMJ C1 J1; Probes1_000152; NSC 71795; BRN 0221300; 5,11-Dimethyl-6H-pyrido(4,3-b)carbazole; CAS-519-23-3; 5,11-Dimethyl-2-azonia-6H-pyrido[4,3-b]carbazole; CCRIS 2003; Prestwick0_000614; NCGC00015411-01; AIDS001996; Neuro_000031; Elliptisine; AC1NRAY8; NSC-71795; MLS000736786; 6H-Pyrido(4,3-b)carbazole, 5,11-dimethyl-; Ellipticine; ICIG 770

分子式:

C17H14N2

Smiles:

CC1=C2C=CN=CC2=C(C3=C1NC4=CC=CC=C43)C

成分:

HBIN025012

OB_score:

30.823362

CAS_id:

519-23-3

SymMap_id:

SMIT00751

TCMID_id:

6758

TCMSP_id:

MOL009135

PubChem_id:

3213


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE002752 Aspidosperma subincanum
TCMBANKHE003778 Lythrum salicaria 千屈菜 To clear heat and resolve toxin, promote contraction and stanch bleeding./Dysentery, diarrhea, hematochezia, flooding, ulcerating sores, blood ejection, spontaneous external bleeding, bleeding due to external injury.
TCMBANKHE007678 Platycarya strobilacea 化香树叶 To resolve toxin and cure sores, kill worms and relieve itch./Swelling toxin of sore and welling abscess, purulence due to bone welling abscess, intractable lichen, scrotal eczema, tinea capitis.
TCMBANKHE004325 Geranium sibiricum 鼠掌老鹳草 See Geranium wilfordii./See Geranium wilfordii.
TCMBANKHE007068 Eucalyptus citriodora 柠檬桉叶 To dissipate wind and eliminate damp, fortify stomach and relieve pain, resolve toxin and relieve itch./Wind-cold common cold, wind-damp bone pain, qi stagnation stomachache, food accumulation, sand distention and vomiting diarrhea, dysentery, asthma, malaria, sore and boil, wind papules, eczema, intractable lichen, burns and scalds.
TCMBANKHE006025 Ochrosia elliptica 古城玫瑰树
TCMBANKHE007520 Fructus Amomi 砂仁 To eliminate damp and improve appetite, to warm the spleen and check diarrhea, and to prevent abortion./Abdominal pain glomus distention, food stagnation in torpid stomach, dysphagia-occlusion, vomiting, cold dysentery, stirring fetus in pregnancy.
TCMBANKHE008574 Herba Agrimoniae 仙鹤草 To arrest bleeding, to stop malarial attacks, to relieve dysentery, and to counteract toxicity./Hemoptysis, blood ejection, flooding and spotting, malaria, blood dysentery, swelling toxin of wellingabscess and sore, pudendal itch, Vaginal discharge.
TCMBANKHE006576/YEM-61/XU-569 Fructus Chebulae|Terminalia chebula Retz.|Terminalia chebula var. tomentella 诃子|微毛诃子 诃子 云南民族药物志:第一卷|云南省临沧市永德县 To check diarrhea and chronic cough, and to soothe the sore throat./Chronic diarrhea and dysentery, hematochezia, prolapse of rectum, cough and asthma due to lung vacuity, incessant cough, aphonia due to throat pain. 阿昌族/傣族/德昂族/景颇族/傈僳族/藏族
TCMBANKHE004574/YEM-665 Poria|Poria cocos(Schw.)Wolf 茯苓 茯苓 云南民族药物志:第四卷 To cause diuresis, to invigorate the spleen function, and to calm the mind./Neurasthenia, disquieted heart spirit, fright palpitation and insomnia, insomnia, pelvic inflammation, edema, scant urine with edema, phlegm-rheum dizziness, reduced food intake due to spleen vacuity, sloppy stool and diarrhea, chronic diarrhea. 阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE007344/YEM-665 Poria; Sclerotium Poriae Cocos; Sclerotium Poriae Cocos|Poria cocos(Schw.)Wolf 茯苓; 云苓|茯苓 茯苓 云南民族药物志:第四卷 To cause diuresis, to invigorate the spleen function, and to calm the mind.; Treatment of edema with oliguria, dizziness and palpitation caused by retained fluid, diminished function of the spleen marked by anorexia, loose stools or diarrhea, restlessness and insomnia./Neurasthenia, disquieted heart spirit, fright palpitation and insomnia, insomnia, pelvic inflammation, edema, scant urine with edema, phlegm-rheum dizziness, reduced food intake due to spleen vacuity, sloppy stool and diarrhea, chronic diarrhea.; 1. An active component pachyman promotes macrophage phagocytosis in mice, and enhances lymphocyte-blastogensis rate in vitro.2. Preventing the formation of gastric ulcer under stress in rats3. Diuretic and liver-protective. 阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE006555/YEM-691 Mangifera indica|Mangifera indica L. 杧果 杧果 云南民族药物志:第四卷 To boost stomach, engender liquid, check vomiting, relieve cough./Thirst, vomiting, reduced food intake, cough. 阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/彝族/藏族/壮族
TCMBANKHE008205/YEM-860/XU-810 Euphorbia hirta|Euphorbia hirta L. 大飞扬草|飞扬草 飞扬草 云南民族药物志:第五卷|云南省昭通市盐津县 To clear heat and resolve toxin, percolate damp and relieve itch, free milk./Acute enteritis, bacillary dysentery, strangury, hematuria, pulmonary welling abscess, mammary welling abscess, clove sore, toxin swelling, eczema, foot lichen, itchy skin. 傣族/哈尼族/基诺族/拉祜族/傈僳族/佤族
TCMBANKHE004691/YEM-353/YEM-961 Fructus Amomi|Amomum villosum Lour. 缩砂仁; 砂仁|阳春砂 阳春砂仁 云南民族药物志:第五卷 Treatment of accumulation of damp in the spleen and the stomach marked by epigastric stuffieness and anorexia, vomiting and diarrhea in deficiency cold syndrome of the spleen and the stomach, pernicious vomiting of pregnancy, threatened abortion.; To eliminate damp and improve appetite, to warm the spleen and check diarrhea, and to prevent abortion./1. Its decoction lower thab 1% concentration stimulates and that higher than 1% or the saturated solution of its volatile oil inhibits the intestines of guinea-pigs in vitro.2. Its volatile oil acts as stomachic tonic and exaggerates the diacharge of flatus.; Abdominal pain glomus distention, food stagnation in torpid stomach, dysphagia-occlusion, vomiting, cold dysentery, stirring fetus in pregnancy. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/瑶族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI007787 Septic Shock phenotype Pathological Conditions, Signs and Symptoms; Infections 31479750

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000047 AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA AKT serine/threonine kinase 1
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000268 NUP62 IBSN; SNDI; p62 nucleoporin 62
TCMBANKGE000707 PTK2B CADTK; CAKB; FADK2; FAK2; PKB; PTK; PYK2; RAFTK protein tyrosine kinase 2 beta
TCMBANKGE000932 AKT2 HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA AKT serine/threonine kinase 2
TCMBANKGE000933 IKBKB IKK-beta; IKK2; IKKB; IMD15; IMD15A; IMD15B; NFKBIKB inhibitor of nuclear factor kappa B kinase subunit beta
TCMBANKGE001072 DNM1L DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; OPA5 dynamin 1 like
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001098 NFKBIA EDAID2; IKBA; MAD-3; NFKBI NFKB inhibitor alpha
TCMBANKGE001114 IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 interleukin 6