Compound Summary

  Compound Information

TCMBANKIN000070

药名:	corynoxine b
别名:	ZINC14686818; SCHEMBL17531555; 17391-18-3
分子式:	C22H28N2O4
Smiles:	CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O
成分:	HBIN021578
SymMap_id:	SMIT14765
TCMID_id:	4120
PubChem_id:	53326136

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE001023	Uncaria cordata	新型钩藤
TCMBANKHE001591	Uncaria attenuata	夏钩藤
TCMBANKHE004610	Ramulus Uncariae cum Uncis	钩藤			To remove heat, subdue hyperactivity of the liver, and arrest convulsions./Infant fright wind and night crying, exuberant heat stirring wind, epilepsy of pregnancy, liver yang dizziness, liver fire headache.
TCMBANKHE007889		杜仲叶			Lumbar and back pain, limp aching inability of legs and knees, hypertension.
TCMBANKHE006899/YNS-5/YEM-284/XU-215	Uncaria sessilifructus [Syn. Nauclea sessilifructus ]|Uncaria sessilifructus Roxb.|Uncaria sessilifructus	白钩藤	白钩藤	云南药材标准：第三册|云南民族药物志：第二卷|广西省来宾市金秀县六段村永新村	清火解毒，消肿止痛，除风通血。用于风湿病肢体关节红肿热痛或酸痛重着；风火气血不和所致的头目胀痛。	彝族
TCMBANKHE008324/YEM-443	Uncaria macrophylla|Uncaria macrophylla Wall.	大叶钩藤	大叶钩藤	云南民族药物志：第三卷	See Uncaria rhynchophylla./See Uncaria rhynchophylla.	傣族/苗族/佤族/彝族/藏族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI017409

Neurodegenerative Disorders

group

Nervous System Diseases

28933595

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000775	MAP2K2	CFC4; MAPKK2; MEK2; MKK2; PRKMK2	mitogen-activated protein kinase kinase 2
TCMBANKGE000835	APP	AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4	amyloid beta precursor protein
TCMBANKGE001044	RPS6KB1	PS6K; S6K; S6K-beta-1; S6K1; STK14A; p70 S6KA; p70(S6K)-alpha; p70-S6K; p70-alpha	ribosomal protein S6 kinase B1
TCMBANKGE001062	PLK1	PLK; STPK13	polo like kinase 1