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Compound Summary

Compound Information

药名:	plumbagin
别名:	plumbagin ; 5-hydroxy-2-methyl-1, 4-naphthoquinone
分子式:	C11H8O3
Smiles:	CC1=CC(=O)C2=C(C1=O)C=CC=C2O
成分:	HBIN040266
CAS_id:	481-42-5
TCMID_id:	17554
PubChem_id:	10205

化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE001574	Plumbago europaea	欧洲蓝茉莉
TCMBANKHE003981	Plumbago indica	紫雪花			To break blood and free menstruation, disperse swelling and relieve pain, dispel wind and kill worms./Amenorrhea, dysmenorrhea, wind-damp impediment pain, sprain from knocks and falls, swelling toxin of welling abscess and sore, scab and lichen.
TCMBANKHE006457	Dionaea muscipula	捕蝇草
TCMBANKHE004834	Ceratostigma plumbaginoides	角柱花			See Ceratostigma willmottianum ./See Ceratostigma willmottianum .
TCMBANKHE006494	Drosera rotundifolia	圆叶茅膏菜			To dispel phlegm, suppress cough, calm asthma, check dysentery./Cough, asthma, pertussis, dysentery.
TCMBANKHE007315	Drosera peltata var. lunata	茅膏菜			To dispel wind and relieve pain, quicken blood, resolve toxin./Wind-damp impediment pain, knocks and falls, taxation damage in lumbar muscle, stomachache, common cold, swelling pain in throat, red and white dysentery, malaria, child gan accumulation, eye screen, scrofula, eczema, scab sore.
TCMBANKHE006401	Plumbagella micrantha	鸡娃草			To kill worms and relieve itch, decay wart and mole./Neurodermatitis, psoriasis, tinea capitis, goose-foot wind, foot lichen, wart.
TCMBANKHE007336/YEM-205	Ceratostigma willmottianum\|Ceratostigma willmottianum Stapf	紫金莲\|岷江蓝雪花	紫金标	云南民族药物志：第一卷	To move qi , quicken blood, settle pain./Knocks and falls, fracture.	傣族/景颇族/彝族
TCMBANKHE008424/YNS-8/YEM-628/XU-108	Plumbago zeylanica\|Plumbago zeylanica Linn.\|Plumbago zeylanica L.	白花丹	白花丹茎叶\|白花丹	云南药材标准：第四册\|云南民族药物志：第四卷\|广西省贵港市平南县安怀镇	舒筋止痛，消肿止痛，明目。用于风湿关节疼痛，跌倒损伤；目障羞明\|To dispel wind and eliminate damp, move qi and quicken blood, resolve toxin and disperse swelling./Wind-damp impediment pain, liver spleen enlargement, amenorrhea due to blood stasis, sprain from knocks and falls, swollen welling abscess and scrofula, scab and lichen with itching, poisonous snake bite.	阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/佤族/瑶族/彝族/壮族

植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000022	Prostatic Neoplasms	group	Neoplasms; Male Urogenital Diseases	26808083
TCMBANKDI000061	Esophageal Neoplasms	group	Digestive System Diseases; Neoplasms	29339720
TCMBANKDI000088	Lung Neoplasms	group	Neoplasms; Respiratory Tract Diseases	24280585
TCMBANKDI003353	Carcinogenesis	phenotype	Pathological Conditions, Signs and Symptoms; Neoplasms	29339720
TCMBANKDI029899	Lymphoma	group	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases	25444924

化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000046	PIK3R1	AGM7; GRB1; IMD36; p85; p85-ALPHA	phosphoinositide-3-kinase regulatory subunit 1
TCMBANKGE000047	AKT1	AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA	AKT serine/threonine kinase 1
TCMBANKGE000052	TNF	DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F	tumor necrosis factor
TCMBANKGE000240	IL17A	CTLA-8; CTLA8; IL-17; IL-17A; IL17	interleukin 17A
TCMBANKGE000251	FGF2	BFGF; FGF-2; FGFB; HBGF-2	fibroblast growth factor 2
TCMBANKGE000305	PIK3CD	APDS; IMD14; P110DELTA; PI3K; p110D	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
TCMBANKGE000306	PIK3CG	PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
TCMBANKGE000307	PIK3CB	P110BETA; PI3K; PI3KBETA; PIK3C1	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
TCMBANKGE000308	PIK3CA	CLAPO; CLOVE; CWS5; MCAP; MCM; MCMTC; PI3K; PI3K-alpha; p110-alpha	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
TCMBANKGE000315	IL4	BCGF-1; BCGF1; BSF-1; BSF1; IL-4	interleukin 4
TCMBANKGE000790	DUSP4	HVH2; MKP-2; MKP2; TYP	dual specificity phosphatase 4
TCMBANKGE000791	DUSP1	CL100; HVH1; MKP-1; MKP1; PTPN10	dual specificity phosphatase 1
TCMBANKGE000792	FASLG	ALPS1B; APT1LG1; APTL; CD178; CD95-L; CD95L; FASL; TNFSF6; TNLG1A	Fas ligand
TCMBANKGE000793	ALDH1A1	ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1	aldehyde dehydrogenase 1 family member A1
TCMBANKGE000794	NANOG	-	Nanog homeobox
TCMBANKGE000795	POU5F1	OCT3; OCT4; OTF-3; OTF3; OTF4; Oct-3; Oct-4	POU class 5 homeobox 1
TCMBANKGE000968	CYCS	CYC; HCS; THC4	cytochrome c, somatic
TCMBANKGE001062	PLK1	PLK; STPK13	polo like kinase 1
TCMBANKGE001085	MAPK8	JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c	mitogen-activated protein kinase 8
TCMBANKGE001089	PARP1	ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1	poly(ADP-ribose) polymerase 1
TCMBANKGE001106	MTOR	FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS	mechanistic target of rapamycin kinase
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE001123	CTNNB1	CTNNB; EVR7; MRD19; NEDSDV; armadillo	catenin beta 1
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001162	IFNG	IFG; IFI	interferon gamma
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001178	STAT3	ADMIO; ADMIO1; APRF; HIES	signal transducer and activator of transcription 3
TCMBANKGE001201	MAPK3	ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK	mitogen-activated protein kinase 3
TCMBANKGE001203	MAPK1	ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK	mitogen-activated protein kinase 1

药名:

plumbagin

别名:

plumbagin ; 5-hydroxy-2-methyl-1, 4-naphthoquinone

分子式:

C11H8O3

Smiles:

CC1=CC(=O)C2=C(C1=O)C=CC=C2O

成分:

HBIN040266

CAS_id:

481-42-5

TCMID_id:

17554

PubChem_id:

10205