Compound Summary


  Compound Information

药名:

Decursin

别名:

decursin; C09258; SMR001397016; MLS002472905; CHEMBL1715398; [(7S)-8,8-dimethyl-2-oxo-6,7-dihydropyrano[5,6-g]chromen-7-yl] 3-methylbut-2-enoate; NCGC00247453-01; Decursinol angelate; (S)-7,8-Dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo(1,2-b:5,4-b')dipyran-7-yl 3-methyl-2-butenoate; 5928-25-6; HMS2198C14; decursin ; 3-methylbut-2-enoic acid [(7S)-8,8-dimethyl-2-oxo-6,7-dihydropyrano[5,6-g]chromen-7-yl] ester; 3-methylbut-2-enoic acid [(7S)-2-keto-8,8-dimethyl-6,7-dihydropyrano[5,6-g]chromen-7-yl] ester; 2-Butenoic acid, 3-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo(1,2-b:5,4-b')dipyran-7-yl ester, (S)-

分子式:

C19H20O5

Smiles:

CC(=CC(=O)OC1CC2=C(C=C3C(=C2)C=CC(=O)O3)OC1(C)C)C

成分:

HBIN022938

OB_score:

39.267206

CAS_id:

5928-25-6

SymMap_id:

SMIT13775;SMIT14934

TCMID_id:

4861

TCMSP_id:

MOL013077

PubChem_id:

44144310


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE002776 白花菜子 Wind-cold sinew and bone numbness, aching pain in back and shoulder, lumbago, swelling pain due to external injury, bone tuberculosis, hemorrhoids and fistulas.
TCMBANKHE003461 紫花前胡
TCMBANKHE004432 Clerodendron cyrtophyllum 路边青 To clear heat and resolve toxin, cool blood and stanch bleeding./Febrile diseases due to external contraction, exuberant heat and vexation thirst, swelling pain in throat, mouth sore, jaundice, heat toxin dysentery, acute enteritis, swelling toxin of welling abscess and flat abscess, spontaneous external bleeding, blood strangury, bleeding due to external injury.
TCMBANKHE005406 Angelica gigas 朝鲜当归 To extinguish wind and harmonize blood./Pain in joints, wrenching and contusion.
TCMBANKHE007994 Herba Humuli Scandentis;Rhaponticum carthamoides 葎草 1. Diurectic. 2. Bacteriostatic. Flower and fruit inhibit the growth of Bacillus tuberculosis and its alcoholic infusion of stemsand leaves inhibits that of gram-positive bacteria in vitro. ;To boost qi and fortify spleen, quiet spirit./Tuberculosis, cystitis, mastitis, tonsillitis, lung heat cough, pulmonary welling abscess, vacuity heat with vexation and thirst, heat strangury, edema, inhibited urination, damp-heat diarrhea dysentery, heat toxin sores, itchy skin.
TCMBANKHE008512 radix Peucedani 前胡 To dispel wind and remove heat, and to relieve cough and resolve phlegm ./Cough, externally contracted wind-heat, lung heat phlegm depression, cough and asthma with abundant phlegm, sticky phlegm, retching counterflow and reduced food intake, fullness and oppression in chest and diaphragm.
TCMBANKHE007557 Herha Ajugae Ciliatae 白毛夏枯草 1. To clear lung-heat, eliminate phlegm and relieve cough. 2. to clear away heat and toxic material, and relieve carbuncle. 3. Clear away heat to cool the blood. 4. Lower blood pressure./Swelling pain in throat, lung heat cough, pulmonary welling abscess, red eyes with gall, dysentery, swollen welling abscess and clove sores, poisonous snake bite, knocks and falls.
TCMBANKHE006781/YEM-333 Radix Saposhnikoviae divaricatae|Saposhnikovia divaricata (Turcz.)Schischk. 防风 防风 云南民族药物志:第二卷 To induce diaphoresis, to dispel wind, to alleviate rheumatic conditions, and to relieve spasm./Migraine, headache and generalized pain, common cold, rheumatoid arthritis, externally contracted wind-cold, wind-damp impediment pain, aching pain in joints, abdominal pain and diarrhea, intestinal wind bleeding, tetanus, wind papule itching, sores. 阿昌族/傣族/德昂族/景颇族/傈僳族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000088 Lung Neoplasms group Neoplasms; Respiratory Tract Diseases 26661339
TCMBANKDI007361 Multiple Myeloma disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases 21122982

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000241 CASP8 ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 caspase 8
TCMBANKGE000289 EIF2AK3 PEK; PERK; WRS eukaryotic translation initiation factor 2 alpha kinase 3
TCMBANKGE000297 JAK2 JTK10; THCYT3 Janus kinase 2
TCMBANKGE000875 ATF4 CREB-2; CREB2; TAXREB67; TXREB activating transcription factor 4
TCMBANKGE001011 TNFSF10 APO2L; Apo-2L; CD253; TL2; TNLG6A; TRAIL TNF superfamily member 10
TCMBANKGE001014 TNFRSF10B CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9 TNF receptor superfamily member 10b
TCMBANKGE001045 CCND1 BCL1; D11S287E; PRAD1; U21B31 cyclin D1
TCMBANKGE001131 CASP9 APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 caspase 9
TCMBANKGE001148 VEGFA MVCD1; VEGF; VPF vascular endothelial growth factor A
TCMBANKGE001156 CASP3 CPP32; CPP32B; SCA-1 caspase 3
TCMBANKGE001166 BCL2 Bcl-2; PPP1R50 BCL2 apoptosis regulator
TCMBANKGE001169 BCL2L1 BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 BCL2 like 1
TCMBANKGE001178 STAT3 ADMIO; ADMIO1; APRF; HIES signal transducer and activator of transcription 3