Compound Summary


  Compound Information

药名:

nitidine

别名:

I14-18057; CHEMBL176008; 6872-57-7; 933301178Z; NCI60_000995; CTK5C8373; CHEBI:7578; FT-0686666; ZINC898732; SCHEMBL8014101; C09595; AK608233; 2,3-Dimethoxy-12-methyl-9H-phenanthridino[4',3'-2,1]benzo[4,5-d]1,3-dioxolane; N2626; 16,17-DIMETHOXY-21-METHYL-5,7-DIOXA-21-AZAPENTACYCLO[11.8.0.0(2),(1)?.0?,?.0(1)?,(1)?]HENICOSA-1(13),2(10),3,8,11,14(19),15,17,20-NONAEN-21-IUM; Nitidine; Nitidine chloride; AKOS015904022; NCIMech_000542; (1,3)Benzodioxolo(5,6-c)phenanthridinium, 2,3-dimethoxy-12-methyl-; 13063-04-2 (CHLORIDE); Ambap13063-04-2; AJ-24283; AC1L1IB4; broussopapyrine A; UNII-933301178Z; ZB015155; CCG-35985; DTXSID60218846; [1,3]Dioxolo[4',5':4,5]benzo[1,2-c]phenanthridinium,2,3-dimethoxy-12-methyl-; AC1Q701O; 2,3-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium; Neuro_000081; BDBM50017566

分子式:

C21H18NO4+

Smiles:

C[N+]1=CC2=CC(=C(C=C2C3=C1C4=CC5=C(C=C4C=C3)OCO5)OC)OC

成分:

HBIN037045

OB_score:

18.580184

CAS_id:

6872-57-7

SymMap_id:

SMIT00225

TCMID_id:

15622

TCMSP_id:

MOL005101

PubChem_id:

4501


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000810 Radix Zanthoxyli 两面针 To promote the flow of qi, relieve pain, to eliminate blood stasis, to promote blood circulation and dispel wind./Treatment of traumatic injury, rheumatic arthralgia, stomach-ache, teethache, bitten by venomous snake, applied for burn caused by hot liquid or fire.
TCMBANKHE002149 楮实子
TCMBANKHE003724 Rhizoma Curcumae longae 姜黄 To eliminate blood stasis, promote the flow of qi, stimulate menstrual discharge and relieve pain./Gallstones, jaundice, leukaemia in early stage and carcinoma of uterine cervix in early stage, chronic ulcer, chronic scab, blood stasis and qi stagnation, pain in chest and abdomen and rib-side, dysmenorrhea, amenorrhea, postpartum stasis stagnation abdominal pain, wind-heat impediment pain, knocks and falls, swollen welling abscess.
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE004060 Zanthoxylum ailanthoides 樗叶花椒 To warm center, dry damp, kill worms, relieve pain./Cold pain in heart and abdomen, cold rheum, diarrhea, cold dysentery, damp impediment, red and white vaginal discharge, toothache.
TCMBANKHE004459 Fructus Lycii 枸杞子 To benefit the liver and the kidney, to replenish vital essence and to improve eyesight./Lassitude in lumbus and knees, emission, dizziness and dim vision, lung disease with cough, diabetes mellitus.
TCMBANKHE004543 Zanthoxylum cuspidatum 花椒簕 To quicken blood, dissipate stasis, relieve pain./Stasis stagnation pain in stomach duct and abdomen, knocks and falls.
TCMBANKHE004593 Zanthoxylum dissitum 大叶花椒根 To dispel wind and dissipate cold, rectify qi and quicken blood./Wind-cold-damp impediment, qi stagnation and pain in stomach duct, cold mounting with abdominal pain, toothache, knocks and falls.
TCMBANKHE004717 Zanthoxylum dissitum 大叶花椒 To dissipate cold and relieve pain, regulate menstruation./Mounting qi (hernia), profuse menstruation.
TCMBANKHE004829 Zanthoxylum myriacanthum 大叶臭花椒 To dispel wind-damp, resolve toxin and disperse swelling, stanch bleeding and relieve pain./Wind-cold common cold, wind-damp impediment pain, fracture due to knocks and falls, bleeding due to external injury, burns and scalds, poisonous snake bite.
TCMBANKHE005000 Pericarpium Zanthoxyli 花椒 To warm the spleen and the stomach and relieve pain, to kill worms, and to relieve itching./Spleen-stomach vacuity cold, cold pain in stomach duct and abdomen, vomiting, diarrhea, abdominal pain and vomiting due to roundworm.
TCMBANKHE005188 Zanthoxylum americanum [Syn. Xanthoxylum americanum] 美洲花椒
TCMBANKHE007665 Zanthoxylum ailanthoides 樗叶花椒根 To dispel wind and eliminate damp, quicken blood and dissipate stasis, disinhibit water and disperse edema./Wind-damp impediment pain, abdominal pain and diarrhea, inhibited urination [=dysuria], bleeding due to external injury, knocks and falls, poisonous snake bites.
TCMBANKHE009084 Zanthoxylum clava- hercules 美国刺椒
TCMBANKHE006130 Zanthoxylum ailanthoides 樗叶花椒皮 To dispel wind and eliminate damp, free network vessels and relieve pain, disinhibit urine./Wind-cold-damp impediment, pain in lumbus and knees, knocks and falls, abdominal pain and diarrhea, inhibited urination, toothache, eczema, scab and lichen.
TCMBANKHE007233 Zanthoxylum flavum 黄心花椒
TCMBANKHE006349 Zanthoxylum avicennae 鹰不泊 To dispel wind and transform damp, disperse swelling and free network vessels./Swelling pain in throat, yellow swelling, malaria, wind-damp bone pain, contusion from knocks and falls.
TCMBANKHE008028 Zanthoxylum echinocarpum 刺壳花椒 To disperse food and assisting movement, move qi and relieve pain./Spleen weakness and functional weakness, reduced food intake with abdominal distention, qi stagnation and pain in stomach duct.
TCMBANKHE007829 Pericarpium Zanthoxyli 花椒 To warm the spleen and the stomach and relieve pain, to kill worms, and to relieve itching./Spleen-stomach vacuity cold, cold pain in stomach duct and abdomen, vomiting, diarrhea, abdominal pain and vomiting due to roundworm.
TCMBANKHE003964/YEM-214/XU-446 Zanthoxylum nitidum|Zanthoxylum nitidum (Roxb.)DC 入地金牛|两面针 两面针 云南民族药物志:第二卷|广东省廉江市石岭镇 To dispel wind and free network vessels, disperse swelling and relieve pain./Wind-damp bone pain, stomachache, toothache, throat impediment, scrofula, burns and scalds. 傣族/哈尼族
TCMBANKHE005663/YNS-73/YEM-663 Toddalia asiatica|Toddalia asiatica (L.) Lam.|Toddalia asiatica(L.)Lam. 飞龙掌血 飞龙掌血茎|飞龙掌血 云南药材标准:第四册|云南民族药物志:第四卷 活血止痛,祛风散寒。用于胃脘疼痛;腰痛,寒湿痹痛,跌倒损伤;皮肤瘙痒|To dispel wind and relieve pain, stanch bleeding and dissipate stasis./Wind-damp Pain, stomachache, knocks and falls, blood ejection, spontaneous external bleeding, knife wound, amenorrhea, dysmenorrhea. 阿昌族/布依族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/佤族/瑶族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1