Compound Summary


  Compound Information

药名:

leonurine

别名:

ST24030828; DTXSID70179434; CHEBI:80843; S-2878; Benzoic acid, 4-hydroxy-3,5-dimethoxy-, 4-[(aminoiminomethyl)amino]butyl ester; Ambotz24697-74-3; HY-N0741; MolPort-003-986-659; KS-000001AK; 7097-09-8; 4-carbamimidamidobutyl 4-hydroxy-3,5-dimethoxybenzoate; DS-1032; AC1L4PH9; 4-guanidinobutyl 4-hydroxy-3,5-dimethoxy-benzoate; ZINC5998954; 4-(diaminomethylideneamino)butyl 4-hydroxy-3,5-dimethoxybenzoate; 4-(diaminomethylideneamino)butyl 4-hydroxy-3,5-dimethoxy-benzoate hydrochloride; Leonurine-hydrochloride; FT-0659198; 697L743; CHEMBL1290284; AKOS025395615; N1392; CS-6071; 4-hydroxy-3,5-dimethoxybenzoic acid 4-guanidinobutyl ester; UNII-09Q5W34QDA; SC-45204; C16985; Benzoic acid, 4-hydroxy-3,5-dimethoxy-, 4-((aminoiminomethyl)amino)butyl ester; 09Q5W34QDA; SCM-198; VA11156; 4-(diaminomethylideneamino)butyl 4-hydroxy-3,5-dimethoxy-benzoate; MolPort-028-751-518; AN-3671; AB0023697; 4CH-009045; MFCD09839432; AK-39841; 4-Guanidino-n-butyl syringate; 7097/9/8; TL8002025; SCHEMBL2685302; BR-39841; 4-GUANIDINOBUTYL 4-HYDROXY-3,5-DIMETHOXYBENZOATE; Leonurine; 24697-74-3; W4810; Leonurine hydrochloride; AKOS015920020; 4-hydroxy-3,5-dimethoxy-benzoic acid 4-guanidinobutyl ester; D08KHD; AJ-64863

分子式:

C14H21N3O5

Smiles:

COC1=CC(=CC(=C1O)OC)C(=O)OCCCCN=C(N)N

成分:

HBIN032907

CAS_id:

24697-74-3

SymMap_id:

SMIT01479;SMIT03865

TCMID_id:

12641

TCMSP_id:

MOL001445

PubChem_id:

161464


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000946 Flos Mume 梅花 To ease the mind, the regulate the stomach function, to resolve phlegm, and counteract toxicity./Treament of depression with fidgetness, epigastric pain due to stagnation of qi of the liver and stomach, globus hystericus, scrofula, ulcers.
TCMBANKHE004699 fructus hippophae 沙棘
TCMBANKHE002732 蚕沙 1. Treatment of damp-heat obstruction syndrome. Silkworm excrement (Cansha) is used with Tetrandra root (Fangji), Coix seed (Yiyiren) and Talc (Huashi) in the formula Xuanbi Tang .2. Eczema. The decoction of the herb is used for external washing. 3. Treat
TCMBANKHE003426 Fructus Leonuri 茺蔚子 To activate blood circulation and regulate menstruation, to subdue hyperactivity of the liver, and to clear the eye of opacity./Treatment of menstrual disorders, amenorrhea, hysmenorrhea, inflammation of the eye with formation of corneal opacity, dizziness and headache.
TCMBANKHE004298 Calyx Kaki 柿蒂 To check the upward flow of the stomach qi./Hiccough.
TCMBANKHE005422 Herba Leonuri,Leonurus cardiaca 益母草,欧益母草,胃益母草 1. To promote blood circulation to remove blood stasis, regulate menstruation and relieve metrorrhagia. 2. To promote diuresis and relieve edema. 3. To clear heat and toxic materials. 4. Lower blood pressure./Menstrual disorder, dysmenorrhea, amenorrhea, postpartum bleeding, persistent flow of lochia, edema, scant urine with edema, acute nephritis with edema.
TCMBANKHE008565 Rehmannia glutinosa [Syn. Rehmannia glutinosa f. huechingensis] 干地黄 To enrich yin and clear heat, cool blood and supplement blood, lower blood sugar levels./Diabetes mellitus, dermatitis, rheumatism, diphtheria, acute tonsillitis, febrile diseases with vexation and thirst, steaming bone taxation fever, warm disease macular eruption, blood ejection due to blood heat, spontaneous external bleeding due to blood heat, flooding and spotting due to blood heat, hematuria due to blood heat, hematochezia due to blood heat, anemia with yellow complexion, palpitation and dizziness, blood depletion and amenorrhea.
TCMBANKHE008586 Leonurus sibiricus 细叶益母草 See Leonurus heterophyllus./See Leonurus heterophyllus.
TCMBANKHE006428 Herba Cistanches 肉苁蓉 To reinforce the kidney, replenish vital essence and blood, and induce Taxation./Impotence, infertility, backache, limp aching lumbus and knees, weakness in sinews and bones, intestinal dry and constipation.
TCMBANKHE007973 Herba Artemisiae Scopariae 茵陈 To remove damp-heat and relieve jaundice./1. Its decoction or its volatile oil, and active components such as chlorogenic acid, caffeic acid and hydroxyacetophenone are chologogues.2. Protecting the liver of experimental animals from the damage of CCl4.3. Decreasing the level of blood lipids and alleviating artherosclerosis and lipidosis in rabbits.4. Increasing the coronary flow of rabbits in vitro.5. Its volatile oil inhibits the growth of Shigella dysenteriae, Hemolytic streptococcus and various dermatomyces in vitro.6. Anticoagulative.
TCMBANKHE004643/YEM-590/XU-716 Folium Mori|Morus alba L.|Morus alba 桑叶|桑 桑叶 云南民族药物志:第三卷|云南省昭通市盐津县 To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision. 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE008630/YEM-638 Fructus tsaoko|Amomum tsao-ko Crevost et Lemarie 草果 草果 云南民族药物志:第四卷 To remove cold-damp from the spleen and the stomach,and to stop malarial attacks./Treatment of accumulation of cold-damp in the spleen and the stomach manifested by epigastric distension, fullness and pain accompanied by vomiting, malaria with paroxysms of chills and fever. 阿昌族/傣族/德昂族/回族/哈尼族/基诺族/傈僳族/佤族/彝族/藏族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI013888 Fibrosis phenotype Pathological Conditions, Signs and Symptoms 23127783
TCMBANKDI019632 Myocardial Infarction disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 23127783

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000224 AGT ANHU; SERPINA8; hFLT1 angiotensinogen
TCMBANKGE000321 NOX4 KOX; KOX-1; RENOX NADPH oxidase 4
TCMBANKGE001037 MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 matrix metallopeptidase 2
TCMBANKGE001118 MMP9 CLG4B; GELB; MANDP2; MMP-9 matrix metallopeptidase 9
TCMBANKGE001201 MAPK3 ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK mitogen-activated protein kinase 3
TCMBANKGE001203 MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK mitogen-activated protein kinase 1