Compound Summary
Compound Information
药名: | juglone |
别名: | Nucin; Iuglon; AIDS-005215; Spectrum2_000778; Spectrum3_001228; HMS503M13; DB-005382; KBio2_007606; cMAP_000058; UNII-W6Q80SK9L6; Antibiotic PD7; NCGC00095247-05; SCHEMBL34185; KBioGR_000497; KBio2_000497; AC1L1GR8; Walnut extract; NSC153189; 5-hydroxy-1,4-naphtoquinone; 1,4-Naphthalenedione,5-hydroxy-; HMS3403I19; HMS1990I19; MFCD00001684; KBio3_000913; BG01503871; QC-1358; Caswell No. 515AA; IN1286; AC1Q6B0X; 5-hydroxy-1,4-dihydronaphthalene-1,4-dione; RTR-030750; NSC-153189; BSPBio_001157; AB0019716; HMS1362I19; SPBio_000856; NSC 622948; Regianin; AIDS005215; KQPYUDDGWXQXHS-UHFFFAOYSA-N; AC1Q794F; 5-Hydroxy-1,4-naphthosemiquinone; NCGC00095247-01; 5-Hydroxy-1,4-naphthoquinone; V0179; SPECTRUM300038; Bio1_000441; C.I. Natural Brown 7; KBio3_000914; H47003_ALDRICH; 5-hydroxy-1,4- naphthalenedione; ST5330598; LS-2142; Akhnot; MolPort-000-725-926; 8-Hydroxy-1,4-naphthalenedione; BDBM24777; SMP1_000168; KBio2_003065; WLN: L66 BV EVJ GQ; KBio2_002470; NCI 2323; 1,4-NAPHTHALENEDIONE, 5-HYDROXY-; C.I. 75500; KBioSS_000497; juglone ; 5-Hydroxy-1,4-naphthalenedione; KBio3_002176; KBio2_003463; Juglane; KBio2_005633; D0C0NH; KS-0000195Q; Bio2_000409; 5-Hydroxy-[1,4]Naphthoquinone; 5-Hydroxy-1,4-naphthoquinone, 97%; Spectrum5_000357; Bio1_000930; KBio1_001026; NCGC00095247-03; 5-Hydroxy-1,4-naphthalenedione, 9CI; 5-Hydroxy-p-naphthoquinone; KBio2_005038; EINECS 207-567-5; 1,4-dihydro-1,4-dioxo-5-hydroxynaphthalene; 5-Hydroxynaphthalene-1,4-dione; D02FPF; 5-HNQ; Walnut Extract; CCG-40256; AN-23490; IDI1_002164; CHEBI:15794; AM20040546; KBioGR_002257; 5-hydroxy-naphthalene-1,4-dione; ZINC00526257; CHEMBL43612; 5-Hydroxy-1,4-naftochinon [Czech]; NCGC00095247-04; 1, 8-hydroxy-; KB-73530; 5-Hydroxy-1,4-naftochinon; HMS1792I19; J-650071; CTK8B1734; 1,4-Naphthoquinone, 5-hydroxy-; FCH1114383; ACN-049171; W6Q80SK9L6; NSC-34266; NSC622948; IDI1_001026; Juglon; Oil Red BS; Avastin+/-Tarceva; Q-100522; BSPBio_002676; NCGC00095247-02; DTXSID0031504; C-05811; DivK1c_001026; 1,4-Naphthoquinone, 5-hydroxy- (8CI); SDCCGMLS-0066542.P001; C03840; 5-Hydroxy-1,4-naphthlenedione; 3b7j; KBio2_006031; ANW-30636; AKOS001576598; F0451-0746; KBioGR_002470; JUG; 1,4-Naphthalenedione, 5-hydroxy-; HMS1923G07; I14-6718; NSC 153189; CC-21839; Spectrum_000415; InChI=1/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12; Jugnlon; KBioSS_002477; ACM481130; 59990_FLUKA; AK307307; CCRIS 5423; ZB014304; Yuglon; ZINC526257; KBio2_000895; 5-Hydroxynaphthoquinone; KBioSS_000895; D08PZH; 4-08-00-02368 (Beilstein Handbook Reference); KBio3_002948; NINDS_001026; BRN 1909764; Bio1_001419; NSC-622948; SR-05000002406-1; 5-hydroxy-1,4-naphthoquinone; MCULE-5238429657; 8-Hydroxy-1,4-naphthoquinone; Juglone; NSC34266; FT-0627559; 481-39-0; 1,4-Naphthoquinone, 8-hydroxy-; ACMC-1AFTN; CI 75500; Bio2_000889; Spectrum4_001769; SR-05000002406; 5-hydroxy-1,4-naphthoquinone, 4; ST50330598 |
分子式: | C10H6O3 |
Smiles: | C1=CC2=C(C(=O)C=CC2=O)C(=C1)O |
成分: | HBIN031581 |
OB_score: | 25.74305 |
CAS_id: | 481-39-0 |
SymMap_id: | SMIT00289 |
TCMID_id: | 11900 |
TCMSP_id: | MOL009115 |
PubChem_id: | 3806 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE000086 | 化香树果 | |||||
| TCMBANKHE001093 | 胡桃花 | |||||
| TCMBANKHE001341 | 胡桃油 | |||||
| TCMBANKHE001818 | 油胡桃 | |||||
| TCMBANKHE004582 | Semen Juglandis | 核桃仁 | To tonify the kidney, to warm the lung, and to relax the bowels./It contains about 50% of fatty oil, exerting antitussive effect. | |||
| TCMBANKHE002097 | 胡桃根 | |||||
| TCMBANKHE002931 | 胡桃壳 | |||||
| TCMBANKHE003256 | 胡桃枝 | |||||
| TCMBANKHE007678 | Platycarya strobilacea | 化香树叶 | To resolve toxin and cure sores, kill worms and relieve itch./Swelling toxin of sore and welling abscess, purulence due to bone welling abscess, intractable lichen, scrotal eczema, tinea capitis. | |||
| TCMBANKHE006218 | Juglans nigra | 黑胡桃 | ||||
| TCMBANKHE004773 | Herba Pteridis multifidae | 凤尾草 | 1. To clear heat and toxic material. 2. To cool the blood and stop bleeding./Dysentery, diarrhea, strangury-turbidity, vaginal discharge, jaundice, swelling toxin of clove sore, throat impediment with nipple moth, scrofula, parotitis, mastitis, ardent fever and convulsion, snake or insect bites, blood ejection, spontaneous external bleeding, hematuria, hematochezia, bleeding due to external injury. | |||
| TCMBANKHE004774 | Carya illinoensis | 美国山核桃 | ||||
| TCMBANKHE007534 | Carya ovata | 粗皮山核桃 | ||||
| TCMBANKHE005907/XU-487 | Speranskia tuberculata | 透骨草|地构叶 | 内蒙古赤峰市阿鲁科尔沁旗 | To dispel wind and eliminate damp, soothe sinews and quicken blood, relieve pain./Wind-damp impediment pain, contracture of muscles and joints, beriberi, swelling toxin of sore and lichen. | ||
| TCMBANKHE004332/YEM-378/XU-663 | Foeniculum vulgare|Foeniculum vulgare Mill. | 茴香茎叶|茴香 | 小茴香 | 云南民族药物志：第二卷|云南省玉溪市澄江县 | To expel wind, normalize qi, relieve pain./Sand qi, mounting qi, swollen welling abscess. | 白族/布依族/傣族/傈僳族/纳西族/彝族/藏族/壮族 |
| TCMBANKHE004583/YEM-60/XU-35 | Juglans regia|Juglans regia L. | 胡桃仁|胡桃|核桃树根 | 核桃 | 云南民族药物志：第一卷|云南省楚雄彝族自治州永仁县永仁古镇农贸市场 | To supplement kidney and boost essence, warm lung and settle asthma, moisten intestines and free stool./Enduring cough and asthma, bronchitis, lumbago and limp leg, frequent urination, enuresis, impotence, emission, intestinal dry and constipation, stone strangury, sores and scrofula. | 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族 |
| TCMBANKHE008816/YEM-60/XU-35 | Juglans regia|Juglans regia L. | 胡桃树皮|胡桃|核桃树根 | 核桃 | 云南民族药物志：第一卷|云南省楚雄彝族自治州永仁县永仁古镇农贸市场 | To astringe intestines and check diarrhea, resolve toxin, relieve itch./Diarrhea, dysentery, leprosy, scrotal wind, itchy skin. | 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族 |
| TCMBANKHE004656/YEM-60/XU-35 | Juglans regia|Juglans regia L. | 胡桃叶|胡桃|核桃树根 | 核桃 | 云南民族药物志：第一卷|云南省楚雄彝族自治州永仁县永仁古镇农贸市场 | To promote contraction and check discharge, kill worms, disperse swelling./Vaginal discharge, scab sore, elephantiasis. | 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族 |
| TCMBANKHE003794/YEM-60/XU-35 | Juglans regia|Juglans regia L. | 胡桃青皮|胡桃|核桃树根 | 核桃 | 云南民族药物志：第一卷|云南省楚雄彝族自治州永仁县永仁古镇农贸市场 | To relieve pain, relieve cough, check diarrhea, resolve toxin, kill worms./Pain in stomach duct and abdomen, dysmenorrhea, enduring cough, chronic diarrhea and dysentery, swelling toxin of welling abscess and sore, intractable lichen, bald sores, white patch wind. | 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族 |
| TCMBANKHE003324/YEM-60/XU-35 | Juglans regia L. | 东方核桃|胡桃|核桃树根 | 核桃 | 云南民族药物志：第一卷|云南省楚雄彝族自治州永仁县永仁古镇农贸市场 | 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族 | |
| TCMBANKHE005323/YEM-60/XU-35 | Juglans regia L. | 分心木;核桃仁|胡桃|核桃树根 | 核桃 | 云南民族药物志：第一卷|云南省楚雄彝族自治州永仁县永仁古镇农贸市场 | 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
| TCMBANKDI000017 | Liver Cirrhosis | disease | Pathological Conditions, Signs and Symptoms; Digestive System Diseases | 27439725 |
| TCMBANKDI000062 | Periodontitis | disease | Stomatognathic Diseases | 25512367 |
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000205 | NOS2 | HEP-NOS; INOS; NOS; NOS2A | nitric oxide synthase 2 |
| TCMBANKGE000313 | JUN | AP-1; AP1; c-Jun; cJUN; p39 | Jun proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE000998 | WNT3A | - | Wnt family member 3A |
| TCMBANKGE001046 | PIN1 | DOD; UBL5 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| TCMBANKGE001047 | E2F1 | E2F-1; RBAP1; RBBP3; RBP3 | E2F transcription factor 1 |
| TCMBANKGE001051 | MAP2K7 | JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4 | mitogen-activated protein kinase kinase 7 |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE001085 | MAPK8 | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c | mitogen-activated protein kinase 8 |
| TCMBANKGE001123 | CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | catenin beta 1 |
| TCMBANKGE001203 | MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | mitogen-activated protein kinase 1 |
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