Compound Summary

  Compound Information

TCMBANKIN000383

药名:	Euphol
别名:	CHEMBL465181; (3S,5R,10S,13S,14S,17S)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol; ST24047202; AIDS-064689; ZINC4097719; FT-0698509; AIDS064689; CHEBI:4940; AKOS016010616; Euphol (6CI); AC1L9BGD; (3S,5R,10S,13S,14S)-17-((R)-1,5-Dimethyl-hex-4-enyl)-4,4,10,13,14-pentamethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol; SCHEMBL541497; BG01135940; (20R)-(+)-triucalla-8,24-diene-3beta-ol; AK120346; euphol; (3S,5R,10S,13S,14S,17S)-17-[(1R)-1,5-dimethylhex-4-enyl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol; (3beta,13alpha,14beta,17alpha)-Lanosta-8,24-dien-3-ol; Lanosta-8,24-dien-3-ol, (3.beta.,13.alpha.,14.beta.,17.alpha.)-; Euphadienol; (+)-Euphol; (s)-euphol; (+)-alpha-Euphol; AJ-48007; alpha-Euphol; Eupha-8,24-dienol; C08624; 514-47-6; LMPR0106090002; KB-277032; 13alpha,14beta,17betaH-Lanosta-8,24-dien-3beta-ol (8CI); 7162AB
分子式:	C30H50O
Smiles:	CC(CCC=C(C)C)C1CCC2(C1(CCC3=C2CCC4C3(CCC(C4(C)C)O)C)C)C
成分:	HBIN026184
OB_score:	42.119189
CAS_id:	514-47-6
SymMap_id:	SMIT04810;SMIT15360
TCMID_id:	7610
TCMSP_id:	MOL002597
PubChem_id:	441678

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002206		罗布麻叶
TCMBANKHE003234	Fructus Malvae	冬葵果			To remove heat and induce diuresis, to relieve edema./Treatment of urinary infection with oliguria, edema and thirst.
TCMBANKHE004697	Radix Kansui	甘遂			To cause drastic purgation and expel the retained water./Edema, ascites, flowing rheum in chest, concretion conglomeration accumulation and gathering, epilepsy, cough and asthma, urinar y and fecal stoppage.
TCMBANKHE005729	Semen Euphorbiae	千金子			To cause drastic purgation for treating edema, and eliminate blood stasis for treating masses./Edema, phlegm-rheum, accumulation and distention-fullness, urinary and fecal stoppage, amenorrhea due to blood stasis, intractable impediment, wart.
TCMBANKHE007023		猫眼草			Phlegm-rheum cough asthma, edema, scrofula, scab and lichen, innominate toxin swelling.
TCMBANKHE005495/XU-730	Radix Euphorbiae Pekinensis|Euphorbia pekinensis	京大戟|大戟		陕西省安康市旬阳县	To cause drastic purgation./Treatment of anasarca, hydrothorax and ascites with dyspnea, constipation and oliguria.
TCMBANKHE006399/XU-502	Euphorbia esula var. cyparissoides|Euphorbia esula	细叶大戟|乳浆大戟		内蒙古赤峰市阿鲁科尔沁旗	To resolve toxin and disperse swelling./Swelling of sores.
TCMBANKHE007327/XU-758	Euphorbia royleana	霸王鞭		云南省普洱市镇沅县	To dispel wind and resolve toxin, kill worms and relieve itch./Sore toxin, skin lichen, edema.
TCMBANKHE006439/XU-822	Macaranga tanarius	血桐		云南省文山州富宁县
TCMBANKHE008576/YEM-567	Euphorbia antiquorum|Euphorbia antiquorum L.	火殃勒	金刚纂	云南民族药物志：第三卷	To disinhibit urine and free stool, draw out toxin and remove putrid, kill worms and relieve itch./Edema, ascites, diarrhea, dysentery, food accumulation, lump glomus, clove sore, welling absc ess and flat abscess, scab and lichen.	阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/佤族/瑶族/彝族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000168	NR3C1	GCCR; GCR; GCRST; GR; GRL	nuclear receptor subfamily 3 group C member 1
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000737	PGR	NR3C3; PR	progesterone receptor
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor