Compound Summary

  Compound Information

TCMBANKIN001863

化合物待补充

药名:	gamma-aminobutyric acid
别名:	NCGC00015043-01; gamma Aminobutyric acid; GABA hydrochloride; Piperidinic acid; Spectrum3_001385; NINDS_000616; NSC 27418; 4-Aminobutyric acid hydrochloride; LMFA01100039; gamma-Aminobutanoic acid; gamma-Aminobutyric acid; QPGLUEKHBNOAHG-UHFFFAOYSA-N; NCGC00024546-03; 28805-76-7; Aminalon; Gamarex; Tocris-0344; D00058; Oprea1_584567; DF 468; 3131-86-0; Butyric acid, 4-amino- (7CI,8CI); Immu-G; EU-0100005; NSC32044; 5959-35-3; 4-aminobutyrate hydrochloride; MCULE-3615304273; Chemical Name: .gamma.-Aminobutanoic acid; InChI=1/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7; NCGC00024546-04; SPECTRUM1500678; BUTANOIC ACID,4-AMINO 4-AMINO,BUTYRIC ACID; 0S3LEB8Q58; gamma-Aminobutyric acid-carboxy-14C; Gamastan; BSPBio_002970; PDSP1_001275; Gammalon; Spectrum2_001208; gamma-Aminobuttersaeure; 56-12-2; a-Aminobutyric acid; Gamulin; nchembio.78-comp12; Gaballon; AC1L4OHW; gamma-Aminobutyric acid hydrochloride; PDSP2_001259; SMR000058285; KBio1_000616; 4-NH2-but; Butanoic acid,4-amino-, hydrochloride (1:1); Acide amino-4- butyrique [French]; 4-aminobutyrate; MLS000028505; EINECS 227-724-1; DTXSID50208256; 4-aminobutyric acid; NCGC00024546-01; KBio2_005565; ST5330631; Butanoic acid, amino-; AK498572; CCG-213774; 4-Aminobutyric acid HCl; Reanal; BG00901312; EPA Pesticide Chemical Code 030802; Gamma-Aminobutyric acid (JAN); UNII-0S3LEB8Q58; gamma-Aminobuttersaeure [German]; NSC27418; AC1Q3E7S; to_000021; Spectrum5_001425; Lopac-A-2129; KBioSS_000429; .gamma.-Aminobutanoic acid; A2129_SIGMA; g-Aminobutyric acid; 56-12-2 (Parent); KBio3_002190; SPBio_000996; Gammalon (TN); 4-NH3-but; NCGC00024546-06; NSC51295; CTK5B0181; Gammalone; Piperidic acid; WLN: Z3VQ; SGCUT00121; IDI1_000616; GABA; EINECS 200-258-6; CCRIS 3721; gamma-aminobutyrate; Spectrum_000049; gamma-Aminobutryic acid; KBio2_000429; KBio2_002997; 70582-09-1; omega-aminobutyric acid; Spectrum4_000809; Aminobutanoic acid; 4-aminobutanoic acid,hydrochloride; butanoic acid, 4-amino-; gamma-amino-n-butyric acid; Mielomade; 4-AMINO-BUTYRATE; GAMMA(AMINO)-BUTYRIC ACID HYDROCHLORIDE; Biomol-NT_000230; 4-aminobutanoic acid hydrochloride(1:1); 4-aminobutanoic acid hydrochloride; 4-aminobutanoate; A5835_SIGMA; Lopac0_000005; GAMMA-AMINO-BUTANOIC ACID; CHEBI:16865; 4-amino-butanoic acid; 4-amino-n-butyric acid; Gammar; C00334; Mielogen; Gamma-aminobutyric acid [JAN]; Gammagee; GAMMA(AMINO)-BUTYRIC ACID; NSC45460; AI3-26812; 3-Carboxypropylamine; A7463_SIGMA; Butyric acid, 4-amino-; .gamma.-Aminobutyric acid; SCHEMBL115987; DivK1c_000616; Gammasol; AKOS024400865; Aminobutyric acid; 4-Aminobutanoic acid; KBioGR_001297; Butanoic acid, 4-amino- (9CI)
分子式:	C4H10ClNO2
Smiles:	C(CC(=O)O)CN.Cl
成分:	HBIN027103
OB_score:	24.089068
CAS_id:	1956-12-02
SymMap_id:	SMIT00035
TCMID_id:	23042
TCMSP_id:	MOL000388
PubChem_id:	210329

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000151	Pheretima Preparata	制地龙			Treatment of high fever with impaired consciousness, convulsions, arthralgia, numbness of the limbs, hemiplegia, cough and asthma due to heat in the lung, edema ano oliguria, hypertension./1. Relaxing bronchial spasm in rats or rabbits.2. Intravenous injection of alcoholic infusion (0.1g/kg) lowers blood pressure in anesthetized dogs.3. Sedative and anticonvulsive.4. Lumbrifebrine, one of its active components, is ab antipyretic.
TCMBANKHE000850	Radix Rehmanniae	生地黄			Treatment of exogenous heat invading at the nutritive and blood levels manifested as dry mouth and deep red tongue proper with scanty coating. Fresh rehmannia root (Shengdihuang) is used with Scrophularia (Xuanshen), Rhinoceros horn (Xijiao) and Ophiopogon root/1. Its decoction exerts a protective effect on experimental hepatitis of mice induced by carbon tetrachloride.2. Gastric feeding or injection of its decoction, water infusion or alcoholic extract can lower the blood sugar level in rabbits (this result is controversial in the recent years).3. Intravenous injection of its extract exerts a hypertensive and diuretic effect in rabbits and dogs.4. Its alcoholic extract shortens the blood coagulation time in rabbits.5. Its water infusion inhibits the growth of some pathogenic fungi.
TCMBANKHE000999		红芪			to promote the drainage of pus and the growth of new tissue.
TCMBANKHE001875	Herba Clinopodii	断血流			To arrest bleeding./Treatment of excessive menstrual discharge, hemorrhage from hysteromyoma, hematuria, epistaxis, gingival bleeding, traumatic bleeding.
TCMBANKHE004633	Setaria italica	粟米			To harmonize center, boost kidney, eliminate heat, resolve toxin./Spleen-stomach vacuity heat, stomach reflux vomiting, reduced food intake with abdominal distention, diabetes mellitus, diarrhea, scalds.
TCMBANKHE002151	Massa Fermentata Rhizpma Pinelliae	半夏曲
TCMBANKHE002175	Rhizoma Pinelliae Preparata	法半夏			Treatment of cough and asthma with copious phlegm, dizziness and palpitation caused by wind-phlegm and phlegm retention, headache due to adverse rising of phlegm./Treatment of cough and asthma with copious phlegm, dizziness and palpitation caused by wind-phlegm and phlegm retention, headache due to adverse rising of phlegm.
TCMBANKHE002659	Concretio Silicea Bambusae	天竺黄			For desolving phlegm
TCMBANKHE002704	Matrinum	苦参碱
TCMBANKHE003091		栝楼茎叶
TCMBANKHE003732	Ganoderma Lucidum seu Japonicum	灵芝(赤芝）			Hyperlipemia, coronary heart disease, angina pectoris, septicemia, carcinoma, hepatitis, vacuity taxation, palpitation, insomnia, dizziness, fatigue hypodynamia, enduring cough and asthma, chronic bronchitis, silicosis.
TCMBANKHE003743	Radix Astragali	黄芪			To reinoforce qi and invigorate the function of the spleen./Common cold, influenza, chronic wound ulcer, chronic glomerulonephritis, diabetes mellitus due to internal heat, qi vacuity edema, chronic gastritis, qi vacuity and hypodynamia, reduced food intake and sloppy stool, center qi fall, chronic diarrhea, prolapse of rectum, hematochezia, flooding and spotting, spontaneous sweating due to exterior vacuity.
TCMBANKHE005508	Bufo bufo gargarizans, Bufo melanostictus	蟾酥			To resolve toxin, relieve pain, open orifices and arouse spirit./Welling abscess and flat abscess with clove sores, swelling pain in throat, summerheat stroke with vomiting and diarrhea, abdominal pain and clouded spirit, local anesthesia.
TCMBANKHE004121	Radix Stemoe	百部			1. To moisten the lungs and stop cough; 2. To kill lice and parasites/Wind-cold cough, pertussis, tuberculosis, senile cough and asthma, ascariasis, oxyuria disease, scab and lichen, eczema, cootie.
TCMBANKHE005929	Radix et Rhizoma Notopterygii	羌活			To relieve pain and rheumatic conditions./Externally contracted wind-cold, headache without sweating, wind-cold-damp impediment, edema, toxin swelling of sores.
TCMBANKHE004459	Fructus Lycii	枸杞子			To benefit the liver and the kidney, to replenish vital essence and to improve eyesight./Lassitude in lumbus and knees, emission, dizziness and dim vision, lung disease with cough, diabetes mellitus.
TCMBANKHE004616		地黄
TCMBANKHE006453	Fructus Momordicae	罗汉果			To remove heat, moisten the lung and relax the bowels./Lung heat dry cough, common cold, throat pain, laryngitis, aphonia due to throat pain, intestinal dry and constipation.
TCMBANKHE004907		连钱草			Treatment of acute urinary infection, urolithiasis, acute jaundice, painful swelling in sores and carbuncies, traumatic injuries.
TCMBANKHE006919	flos farfarae	款冬花			To relieve cough and resolve phlegm to nourish the lung to keep the adverse qi downward./Cough, cough and asthma with abundant phlegm, consumption cough and hemoptysis, chronic bronchitis, infection of upper respiratory tract, tuberculosis.
TCMBANKHE007204	Gallus gallus domesticus	鸡脑			To extinguish wind and check tetany./Difficult delivery, child fright epilepsy, infant night crying.
TCMBANKHE005444		白鲜皮			To clear heat and dry damp, dispel wind and relieve itch, resolve toxin./1. Inhibiting the growth of pathogenic fungi. 2. Its infusion lowers vaccine-induced fever in rabbits. 3. Dictamnine, one of its active components, increase the myocardial tone of frogs. Dermatitis, psoriasis, icterohepatitis, damp-heat sore and papules, profuse pus, yellow-water sore, damp ulceration on skin, itchy skin, damp-heat jaundice, damp-heat impediment.
TCMBANKHE005507	Radix Phytolaccae	商陆			To cause drastic purgation and also diuresis, to counteract toxicity, and to reduce modulation./Edema distention fullness, urinary and fecal stoppage, swelling toxin of welling abscess and sore.
TCMBANKHE008565	Rehmannia glutinosa [Syn. Rehmannia glutinosa f. huechingensis]	干地黄			To enrich yin and clear heat, cool blood and supplement blood, lower blood sugar levels./Diabetes mellitus, dermatitis, rheumatism, diphtheria, acute tonsillitis, febrile diseases with vexation and thirst, steaming bone taxation fever, warm disease macular eruption, blood ejection due to blood heat, spontaneous external bleeding due to blood heat, flooding and spotting due to blood heat, hematuria due to blood heat, hematochezia due to blood heat, anemia with yellow complexion, palpitation and dizziness, blood depletion and amenorrhea.
TCMBANKHE006534	Saccharum sinensis	甘蔗			To clear heat and engender liquid, moisten dryness and harmonize center, resolve toxin./Heat vexation, diabetes mellitus, vomiting nausea, vacuity heat cough, dry stool, swelling of welling abscess, welling abscess and flat abscess with swelling sore.
TCMBANKHE008343	Radix Trichosanthis	天花粉			To remove heat, to promote the production of body fluid, and to facilitate the drainage of pus and the subsidence of swelling./Febrile diseases thirst, lung heat dry cough, diabetes mellitus due to internal heat, toxin swelling of sores, induce abortion.
TCMBANKHE007751	Cortex Fraxini	秦皮			To remove damp-heat, to arrest discharges, and to improve eyesight./1. Inhibiting the growth of dysentery bacillus and staphylococcus.2. Antitussive and expectorant.3. Aesculin, one of its active components, prolongs the hypnotic effect of hexobarbital in mice.4. Aescuktin, another active component, exerts an antihistaminic effect and relaxes smooth muscles of guinea-pig's trachea in vitro.5. Analgesic. The effect of aescuktin is stronger than that of aspirin but weaker than codeine.
TCMBANKHE007230	Rhizoma Pinelliae	半夏			To remove damp and phlegm, to relieve nausea and vomiting, and to eliminate stuffiness in the chest and the epigastrium./Cough and asthma with abundant phlegm, vomiting nausea, glomus in chest, dizziness, headache, vexation and agitation in night, goiters with phlegm node, swelling toxin of welling abscess and flat abscess.
TCMBANKHE007928		白药子			Septicemia, acute hepatitis, bacillary dysentery, parotitis, neurodermatitis, swelling pain in throat, heat toxin swollen welling abscess, wind-damp impediment pain, abdominal pain and diarrhea, blood ejection, bleeding, spontaneous external bleeding, bleeding due to external injury.
TCMBANKHE007295	Radix Aucklandiae	木香			To relieve pain by promoting the flow of qi, and to improve digestion by reinforcing the spleen function. /Distending pain in chest and stomach duct, diarrhea and tenesmus, non-digestion of food accumu lation, no thought of food and drink.
TCMBANKHE008775	Rhizoma Dioscoreae	山药			To replenish the spleen and stomach, to promote fluid secretion and benefit the lung, and to strengthen the kidney and restrain seminal discharge.Rhizoma Dioscoreae (stir-fried with bran) To replenish the spleen and promote the stomach function./Reduced food intake due to spleen vacuity, incessant chronic diarrhea, cough and asthma due to lung vacuity, kidney vacuity and emission, vaginal discharge, frequent urination, vacuity heat and diabetes mellitus.
TCMBANKHE006421/YEM-1037/XU-804	Trichosanthes kirilowii Maxim.|Trichosanthes kirilowii	瓜蒌|栝楼	天花粉	云南民族药物志：第五卷|云南省昭通市盐津县	Angina pectoris, lung heat cough, chest impediment, diabetes mellitus, acute mastitis, constipation, swelling toxin of welling abscess and sore.	苗族/彝族
TCMBANKHE003455/YEM-1037/XU-804	Pericarpium Trichosanthis|Trichosanthes kirilowii Maxim.|Trichosanthes kirilowii	瓜篓皮|栝楼	天花粉	云南民族药物志：第五卷|云南省昭通市盐津县	Treatment of cough with yellowish sticky expectoration, oppressed feeling in the chest and costal pain./Treatment of cough with yellowish sticky expectoration, oppressed feeling in the chest and costal pain.	苗族/彝族
TCMBANKHE001938/YEM-1037/XU-804	Semen Trichosanthis|Trichosanthes kirilowii Maxim.|Trichosanthes kirilowii	瓜篓子|栝楼	天花粉	云南民族药物志：第五卷|云南省昭通市盐津县	Treatment of dry cough with sticky sputum, constipation./Treatment of dry cough with sticky sputum, constipation.	苗族/彝族
TCMBANKHE007689/YEM-173	Hemerocallis fulva var. kwanso|Hemerocallis fulva (L.) L.	重瓣萱草|萱草	萱草	云南民族药物志：第一卷		白族/彝族
TCMBANKHE004546/YEM-320	Citrullus vulgaris [Syn. Citrullus lanatus ]|Citrullus lanatus(Thunb.)Matsum.et Nakai	西瓜	西瓜	云南民族药物志：第二卷	To clear heat and resolve summerheat, resolve summerheat and engender liquid, disinhibit urine./Summerheat-heat vexation and thirst, exuberant heat fluid damage, inhibited urination, throat impediment, mouth sore.	傣族/佤族/壮族
TCMBANKHE004801/YEM-339	Herba Verbae|Verbena officinalis L.	马鞭草	马鞭草	云南民族药物志：第二卷	To promote the flow of blood and to relieve blood stasis, to stop malarial attacks, to counteract toxicity, and to cause diuresis./Malaria, amenorrhea and dysmenorrhea, throat impediment, edema, heat strangury, diphtheria, bilharziosis, dysentery, concretion conglomeration accumulation and gathering.	白族/布朗族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/纳西族/普米族/佤族/彝族/藏族/壮族
TCMBANKHE004643/YEM-590/XU-716	Folium Mori|Morus alba L.|Morus alba	桑叶|桑	桑叶	云南民族药物志：第三卷|云南省昭通市盐津县	To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision.	阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE001443/YEM-631	Rhizoma Pinelliae Preparata|Pinellia ternata(Thunb.)Breit.	制半夏|半夏	半夏	云南民族药物志：第四卷	Treatment of cough and asthma with much phlegm, dizziness and palpitation due to retention of phlegm and fluid, vertigo caused by wind-phlegm, headache with cold extremities due to attack of phlegm , stuffiness in the chest and the epigastrium, globus hystericus. Rhizoma Pineliae (processed with ginger) is often used for relieving nausea and vomiting. Rhizoma pinelliae (Proccessed with alum) for removing damp and phlegm. Rhizoma Pinelliae (unproccessed) is used externally for boils, sores and lymphadenitis./Treatment of cough and asthma with much phlegm, dizziness and palpitation due to retention of phlegm and fluid, vertigo caused by wind-phlegm, headache with cold extremities due to attack of phlegm , stuffiness in the chest and the epigastrium, globus hys	阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/彝族/藏族/壮族
TCMBANKHE004835/YEM-813	Prunus salicina|Prunus salicina Lindl.	李子|李	黄李子	云南民族药物志：第四卷	To clear heat, engender liquid, disperse accumulation./Vacuity taxation with steaming bone, diabetes mellitus, food accumulation.	阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE005203/YEM-999/XU-341	Radix Isatidis seu Baphicacanthi|Isatis indigotica Fort.|Isatis indigotica	板蓝根|菘蓝	板蓝根	云南民族药物志：第五卷|山东省菏泽市	To remove toxic heat, to reduce heat in blood, and to soothe sore throat./Epidemic encephalitis, measles papulis, parotitis, influenza, warm toxin macular eruption, ardent fever with headache, massive head scourge, throat pain, maculopapular eruption, epidemic parotitis, erysipelas, hepatitis, swelling toxin of sore and welling abscess.	回族/彝族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000469	CTSD	CLN10; CPSD; HEL-S-130P	cathepsin D
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE003342	GATM	AGAT; AT; CCDS3	glycine amidinotransferase
TCMBANKGE006364	SLC6A1	GABATHG; GABATR; GAT1; MAE	solute carrier family 6 member 1
TCMBANKGE006886	ADH1A	ADH1	alcohol dehydrogenase 1A (class I), alpha polypeptide
TCMBANKGE008718	PRSS3	MTG; PRSS4; T9; TRY3; TRY4	serine protease 3
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE013383	VCP	CDC48; TERA; p97	valosin containing protein
TCMBANKGE014015	BCHE	BCHED; CHE1; CHE2; E1	butyrylcholinesterase
TCMBANKGE014656	ABAT	GABA-AT; GABAT; NPD009	4-aminobutyrate aminotransferase