Compound Summary
Compound Information
药名: | arachidonic acid |
别名: | (5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoic acid; cis-5,8,11,14-Eicosatetraenoic acid; 3435-81-2; 5Z,8Z,11Z,14Z-icosatetraenoic acid; cis,cis,cis,cis-5,8,11,14-Eicosatetraenoic acid; C00219; ACD; Arachidonsaeure; arachidonicacid; DTXSID40473870; (5Z,8Z,11Z,14Z)-Icosatetraenoic acid; ST069383; 93444-49-6; (14C)Arachidonic acid; NCGC00094608-04; 5,8,11,14-Eicosatetraenoic acid, labeled with carbon-14, (all-Z)-; A3555_SIGMA; 5Z,8Z,11Z,14Z-eicosatetraenoic acid; all-cis-5,8,11,14-eicosatetraenoic acid; IDI1_034009; ARACHIDONIC ACID, [1-14C]-; BSPBio_001539; NCGC00094608-02; NCGC00094608-03; AIDS045704; CHEBI:15843; NCGC00094608-01; (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid; cis-Delta(5,8,11,14)-eicosatetraenoic acid; A3925_SIGMA; ACM3435812; Spectrum5_001910; Arachidonic acid-carboxy-14C; A9673_SIGMA; LMFA01030001; AIDS-045704; 10931_FLUKA; cis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid |
分子式: | C20H32O2 |
Smiles: | CCCCCC=CCC=CCC=CCC=CCCCC(=O)O |
成分: | HBIN016572 |
OB_score: | 45.57325 |
CAS_id: | 93444-49-6 |
SymMap_id: | SMIT00459;SMIT14360 |
TCMID_id: | 23111;1599 |
TCMSP_id: | MOL001439 |
PubChem_id: | 444899 |
DrugBank_id: | DB04557 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE004205 | Lepidium campestre | 荒野独行菜 | ||||
| TCMBANKHE002205 | Fructus Perillae | 紫苏子 | To relieve dyspnea and cough, to eliminate phlegm , and to relax bowels./Treatment of cough and dyspnea due to accumulation of phleg , constipation. | |||
| TCMBANKHE003170 | 鲩鱼 | |||||
| TCMBANKHE003738 | Aloe | 芦荟 | 1. To purge feces; 2. To clear heat in the liver; 3. To kill worms/Constipation, child gan accumulation, ascariasis, fright wind, lichen. | |||
| TCMBANKHE003757 | Matteuccia struthiopteris | 小叶贯众 | To clear heat and resolve toxin, kill worms, stanch bleeding./Febrile diseases macular eruption, parotitis, damp-heat sore toxin, abdominal pain due to ascariasis, oxyuria disease, red dysentery and bloody stool, hematuria, blood ejection, spontaneous external bleeding, flooding and spotting [=metrorrhagia and metrostaxis]. | |||
| TCMBANKHE004022 | Cordyceps | 冬虫夏草 | To tonify the lung and the kidney, arrest bleeding, and dispel phlegm./Impotence and emission, neurasthenia, backache, aching in lumbus and knees, enduring cough and vacuity asthma, taxation damage hemoptysis. | |||
| TCMBANKHE004208 | Thallus Lamiriae | 昆布 | To eliminate phlegm, soften hard masses and dissolve lumps, and to cause diuresis./Goiter and tuberculosis, scrofula, bleeding, painful swollen testes, phlegm-rheum and edema, prevention of cataracts. | |||
| TCMBANKHE005422 | Herba Leonuri,Leonurus cardiaca | 益母草,欧益母草,胃益母草 | 1. To promote blood circulation to remove blood stasis, regulate menstruation and relieve metrorrhagia. 2. To promote diuresis and relieve edema. 3. To clear heat and toxic materials. 4. Lower blood pressure./Menstrual disorder, dysmenorrhea, amenorrhea, postpartum bleeding, persistent flow of lochia, edema, scant urine with edema, acute nephritis with edema. | |||
| TCMBANKHE006287 | Herba Portulacae | 马齿苋 | To remove toxic heat, and to arrest bleeding./Heat toxin blood dysentery, acute bacillary dysentery, pertussis, enteritis, appendicitis, swollen welling abscess and clove sores, eczema, erysipelas, bleeding, postpartum bleeding, hematochezia, bleeding from hemorrhoids, flooding and spotting, ascariasis, ancylostomiasis, snake or insect bites. | |||
| TCMBANKHE006357 | 水飞蓟 | Acute hepatitis, chronic hepatitis, cirrhosis, fatty liver, gallstones, cholangitis. | ||||
| TCMBANKHE008629 | pollen typhae | 蒲黄 | To arrest bleeding, to remove blood stasis, and to relieve dysuria./Hyperlipemia, angina pectoris, exudative eczema, bleeding, hemoptysis, spontaneous external bleeding, blood ejection, hematochezia, hematuria, flooding and spotting, bleeding due to external injury, pain in heart and abdomen, dysmenorrhea, postpartum bleeding, postpartum abdominal pain, blood strangury with inhibited pain. | |||
| TCMBANKHE006691 | Lepidium virginicum | 北美葶苈子 | See Lepidium apetalum ./See Lepidium apetalum. | |||
| TCMBANKHE008658 | Semen Biotae | 柏子仁 | To calm the nerves, to check excessive perspiration, and to relax the bowels./Fright palpitation and fearful throbbing, sleepless and amnesia, night sweating, intestinal dry and constipation. | |||
| TCMBANKHE006854/YNS-181/XU-60/XU-236 | Arctium lappa L.|Arctium lappa | 荜澄茄|牛蒡 | 牛蒡根 | 云南药材标准：第二册|西藏昌都市洛隆县 | 祛风清热，解毒消肿，力气通便。用于咽喉肿痛，牙龈肿痛，咳嗽痰稠，腹胀便秘，消渴；黄白带下，干血痨，产后少乳，风毒面肿，大头风，疮疡肿痛/Stomach cold with retching counterflow, distention fullness, cold pain in stomach duct and abdomen, rumbling intestines and diarrhea, cold mounting with abdominal pain, cold-damp dribbling urination and turbid urine. | |
| TCMBANKHE004087/YEM-220 | Fructus Quisqualis|Quisqualis indica L. | 使君子 | 使君子 | 云南民族药物志：第二卷 | To kill worms./Ascariasis, oxyuria disease, child gan accumulation. | 阿昌族/傣族/德昂族/景颇族/傈僳族/普米族/佤族/瑶族 |
| TCMBANKHE005716/YEM-243 | Semen Canbis;Fructus Canbis;Fructus cannabis|Cannabis sativa L. | 火麻仁;麻子仁|大麻 | 大麻 | 云南民族药物志：第二卷 | To cause Taxation.;Purging by moisterizing/Blood and liquid depletion, intestinal dry and constipation. | 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/彝族/藏族 |
| TCMBANKHE004643/YEM-590/XU-716 | Folium Mori|Morus alba L.|Morus alba | 桑叶|桑 | 桑叶 | 云南民族药物志：第三卷|云南省昭通市盐津县 | To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision. | 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000088 | PPP5C | PP5; PPP5; PPT | protein phosphatase 5 catalytic subunit |
| TCMBANKGE000163 | TNFRSF1B | CD120b; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; p75; p75TNFR | TNF receptor superfamily member 1B |
| TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
| TCMBANKGE000205 | NOS2 | HEP-NOS; INOS; NOS; NOS2A | nitric oxide synthase 2 |
| TCMBANKGE000226 | UCP2 | BMIQ4; SLC25A8; UCPH | uncoupling protein 2 |
| TCMBANKGE000326 | SELP | CD62; CD62P; GMP140; GRMP; LECAM3; PADGEM; PSEL | selectin P |
| TCMBANKGE000390 | ABCC4 | MOAT-B; MOATB; MRP4 | ATP binding cassette subfamily C member 4 |
| TCMBANKGE000532 | PECAM1 | CD31; CD31/EndoCAM; GPIIA'; PECA1; PECAM-1; endoCAM | platelet and endothelial cell adhesion molecule 1 |
| TCMBANKGE000644 | TNFRSF1A | CD120a; FPF; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR55; TNFR60; p55; p55-R; p60 | TNF receptor superfamily member 1A |
| TCMBANKGE000709 | ALDH3A1 | ALDH3; ALDHIII | aldehyde dehydrogenase 3 family member A1 |
| TCMBANKGE000749 | ALOX5 | 5-LO; 5-LOX; 5LPG; LOG5 | arachidonate 5-lipoxygenase |
| TCMBANKGE000764 | TRPV1 | VR1 | transient receptor potential cation channel subfamily V member 1 |
| TCMBANKGE000766 | ACHE | ACEE; ARACHE; N-ACHE; YT | acetylcholinesterase (Cartwright blood group) |
| TCMBANKGE000785 | G6PD | G6PD1 | glucose-6-phosphate dehydrogenase |
| TCMBANKGE000813 | DPP4 | ADABP; ADCP2; CD26; DPPIV; TP103 | dipeptidyl peptidase 4 |
| TCMBANKGE000838 | PTGES | MGST-IV; MGST1-L1; MGST1L1; MPGES; PGES; PIG12; PP102; PP1294; TP53I12; mPGES-1 | prostaglandin E synthase |
| TCMBANKGE000866 | PRKCB | PKC-beta; PKCB; PKCI(2); PKCbeta; PRKCB1; PRKCB2 | protein kinase C beta |
| TCMBANKGE000903 | PTGS1 | COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS | prostaglandin-endoperoxide synthase 1 |
| TCMBANKGE000938 | CDK2 | CDKN2; p33(CDK2) | cyclin dependent kinase 2 |
| TCMBANKGE000973 | EGF | HOMG4; URG | epidermal growth factor |
| TCMBANKGE001045 | CCND1 | BCL1; D11S287E; PRAD1; U21B31 | cyclin D1 |
| TCMBANKGE001053 | ABCG1 | ABC8; WHITE1 | ATP binding cassette subfamily G member 1 |
| TCMBANKGE001054 | ABCA1 | ABC-1; ABC1; CERP; HDLCQTL13; HDLDT1; HPALP1; TGD | ATP binding cassette subfamily A member 1 |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE001107 | NOS3 | ECNOS; eNOS | nitric oxide synthase 3 |
| TCMBANKGE001117 | PTEN | 10q23del; BZS; CWS1; DEC; GLM2; MHAM; MMAC1; PTEN1; PTENbeta; TEP1 | phosphatase and tensin homolog |
| TCMBANKGE001156 | CASP3 | CPP32; CPP32B; SCA-1 | caspase 3 |
| TCMBANKGE001170 | CDK4 | CMM3; PSK-J3 | cyclin dependent kinase 4 |
| TCMBANKGE001184 | RELA | CMCU; NFKB3; p65 | RELA proto-oncogene, NF-kB subunit |
| TCMBANKGE001185 | PPARG | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma | peroxisome proliferator activated receptor gamma |
| TCMBANKGE001203 | MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | mitogen-activated protein kinase 1 |
| TCMBANKGE001547 | ALDH2 | ALDH-E2; ALDHI; ALDM | aldehyde dehydrogenase 2 family member |
| TCMBANKGE003577 | PLA2G4A | GURDP; PLA2G4; cPLA2; cPLA2-alpha | phospholipase A2 group IVA |
| TCMBANKGE004181 | GLB1 | EBP; ELNR1; MPS4B | galactosidase beta 1 |
| TCMBANKGE006010 | RETN | ADSF; FIZZ3; RETN1; RSTN; XCP1 | resistin |
| TCMBANKGE007202 | CETP | BPIFF; HDLCQ10 | cholesteryl ester transfer protein |
| TCMBANKGE007361 | C1R | EDSPD1 | complement C1r |
| TCMBANKGE007432 | PTGES2 | C9orf15; GBF-1; GBF1; PGES2; mPGES-2 | prostaglandin E synthase 2 |
| TCMBANKGE008225 | COL1A2 | EDSARTH2; EDSCV; OI4 | collagen type I alpha 2 chain |
| TCMBANKGE008917 | KCNK2 | K2p2.1; TPKC1; TREK; TREK-1; TREK1; hTREK-1c; hTREK-1e | potassium two pore domain channel subfamily K member 2 |
| TCMBANKGE008921 | RXRA | NR2B1 | retinoid X receptor alpha |
| TCMBANKGE009054 | KCNK10 | K2p10.1; PPP1R97; TREK-2; TREK2 | potassium two pore domain channel subfamily K member 10 |
| TCMBANKGE009256 | SLC6A2 | NAT1; NET; NET1; SLC6A5 | solute carrier family 6 member 2 |
| TCMBANKGE010213 | HERC5 | CEB1; CEBP1 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| TCMBANKGE013504 | RXRG | NR2B3; RXRC | retinoid X receptor gamma |
| TCMBANKGE014941 | DPEP1 | MBD1; MDP; RDP | dipeptidase 1 |
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