Compound Summary


  Compound Information

药名:

histamine

别名:

beta-Aminoethylglyoxaline; 3bu1; IDI1_002144; Bio1_000976; AIDS020252; Histamium; 2-(3H-imidazol-4-yl)ethanamine; Bio1_000487; 5-Imidazoleethylamine; 4-Imidazoleethylamine; NCGC00093371-03; Spectrum3_000452; BCBcMAP01_000250; KBio3_000854; L-histamine; 1H-Imidazole-4-ethanamine; Spectrum4_000960; BSPBio_001117; KBio2_003893; C00388; 2-(1H-imidazol-4-yl)ethanamine; KBio2_000457; KBioSS_000457; Histamine, Free Base; CCRIS 6535; SMR000059091; NSC33792; KBio2_003025; CHEBI:58432; 2-(4-Imidazolyl)ethylamine; BSPBio_002124; Istamina [Italian]; Ergamine; 2-(1H-imidazol-5-yl)ethylazanium; ZERO/004089; HSM; 4-(2-Aminoethyl)-1H-imidazole; Eramin; Spectrum_000845; CJ-15872; Histamine Base; histaminium; .beta.-Imidazolyl-4-ethylamine; histaminium cation; Bio1_001465; beta-Imidazolyl-4-ethylamine; NSC 33792; KBioGR_001580; 3rxh; SMP1_000151; WLN: T5M CNJ D2Z; Histamine [USAN]; Imidazole-4-ethylamine; beta-Aminoethylimidazole; Spectrum2_000665; KBioSS_001325; Ergotidine; KBio3_000853; 2-Imidazol-4-ylethylamine; SDCCGMLS-0066601.P001; 5-(2-Aminioethyl)-1H-imidazole; 2-(3H-imidazol-4-yl)ethylamine; peremin; A828600; 51-45-6; AIDS-020252; HSDB 3338; NCGC00015513-01; HISTAMINE; EINECS 200-100-6; KBio2_005593; Lopac0_000595; nchembio714-comp1; KBio1_000308; MLS000069447; CHEBI:18295; Lopac-H-7250; Ethylamine, 2-imidazol-4-yl-; KBio3_001344; Free histamine; IDI1_000308; H7125_SIGMA; 2-(1H-imidazol-4-yl)ethanaminium; KBioGR_000457; KBio2_006461; ST073926; 53290_FLUKA; FT-0669215; 2-(1H-imidazol-5-yl)ethylammonium; beta-aminothethylglyoxaline; Bio2_000389; Spectrum5_000796; SPBio_000729; Theramine; DivK1c_000308; KBio2_001325; NINDS_000308; NCGC00093371-04; Bio2_000869; Imidazole, 4-(2-aminoethyl)-; 2-(1H-imidazol-5-yl)ethanamine

分子式:

C5H9N3

Smiles:

C1=C(NC=N1)CCN

成分:

HBIN029438

OB_score:

44.104205

CAS_id:

51-45-6

SymMap_id:

SMIT00108

TCMID_id:

9567

TCMSP_id:

MOL001464

PubChem_id:

774


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE004208 Thallus Lamiriae 昆布 To eliminate phlegm, soften hard masses and dissolve lumps, and to cause diuresis./Goiter and tuberculosis, scrofula, bleeding, painful swollen testes, phlegm-rheum and edema, prevention of cataracts.
TCMBANKHE000926 海带根
TCMBANKHE002319 Isodon japonica var. glaucocalyx 蓝萼香茶菜
TCMBANKHE003748 Rhizoma Coptidis 黄连 To remove damp-heat, quench fire and counteract toxicity./Febrile infectious diseases, dysentery, blood ejection, spontaneous external bleeding, diphtheria, infection of upper respiratory tract, scarlatina, typhoid fever, acute conjunctivitis, otitis media, acute surgical infection, septicemia, hepatitis, trichomoniasis, eruptive dermatitis, hypertension, vexation and agitation, clouded spirit with delirious speech, damp-heat glomus in chest, damp-heat diarrhea dysentery, insomnia and vexation due to effulgent fire, stomach heat vomiting, swift digestion with rapid hungering, red eyes with pain due to liver fire, heat toxin sores, clove sore running yellow, gum swelling and pain, mouth sore, tongue sores, genital swelling, bleeding from hemorrhoids, eczema, scalds.
TCMBANKHE003755 Radix Ampelopsis 白蔹 To remove toxic heat, to cure carbuncles, and to reduce nodules./Swelling toxin of sore and welling abscess, burns and scalds, scrofula, damp sore, warm malaria, frightepilepsy, blood dysentery, intestinal wind, hemorrhoids and fistulas, leukorrhea, knocks and falls, bleeding due to external injury.
TCMBANKHE003939 Spinacia oleracea 菠菜 To nourish blood, stanch bleeding, calm liver, moisten dryness./Spontaneous external bleeding, hematochezia, headache, dizziness and dim vision, red eyes, night blindness, diabetes mellitus, fecal stoppage, hemorrhoids.
TCMBANKHE004159 Radix Linderae 乌药 1. To regulate qi and stop pain; 2. To warm the kidneys and dispel cold/Distending pain in chest and abdomen, qi counterflow with rapid asthma, bladder vacuity cold, enuresis and frequent urination, mounting qi , dysmenorrhea.
TCMBANKHE006371 白屈菜 Pain in sensory nerve endings, pain from ulcer in digestive tract, stomachache, abdominal pain, enteritis, dysentery, chronic bronchitis, pertussis, cough, jaundice, edema, ascites, scab and lichen with swelling of sores, snake or insect bites.
TCMBANKHE006643 Gossypium herbaceum 棉花 To stanch bleeding./Blood ejection, hematochezia, flooding, bleeding due to external injury.
TCMBANKHE008903 Scolopendra subspinipes mutilans;Aloe arborescens var. natalensis 蜈蚣 To calm, lower blood pressure, extinguish wind and check tetany, resolve toxin and dissipate binds, free network vessels and relieve pain.To drain fire and resolve toxin, free stool./Acute fright wind, chronic fright wind, tetanus, spasm, convulsion, toxin swelling of sores and open sores, scrofula with ulceration, intractable headache with pulling sensation, wind-damp impediment pain, hypertension.Liver fire and red eyes, dizziness, lung heat cough asthma, repletion heat constipation, swelling pain of welling abscess and sore, erythematous lupus.
TCMBANKHE004886 Anguilla japonica 鳗鲡鱼 To fortify spleen and supplement lung, dispel wind and eliminate damp, resolve toxin and kill worms./Indigestion, child gan accumulation, tuberculosis with cough, impotence, flooding and spotting with vaginal discharge, beriberi with edema, wind-damp bone pain, intestinal wind, dysentery, sore, hemorrhoids and fistulas, malaria, intestinal parasitic disease.
TCMBANKHE005002 Claviceps purpurea 麦角 To contract uterus and stanch bleeding, relieve pain./Postpartum bleeding, migraine.
TCMBANKHE008053 Apis cerana 蜂毒 To dispel wind and eliminate damp, relieve pain./Rheumatic arthritis, aching pain in lumbus muscle, neuralgia, hypertension, urticaria, asthma.
TCMBANKHE005507 Radix Phytolaccae 商陆 To cause drastic purgation and also diuresis, to counteract toxicity, and to reduce modulation./Edema distention fullness, urinary and fecal stoppage, swelling toxin of welling abscess and sore.
TCMBANKHE008006 Urtica dioica 异株荨麻 See Urtica cannabina./See Urtica cannabina.
TCMBANKHE005687 Cyprinus carpio 鲤鱼 To fortify spleen and harmonize stomach, disinhibit water and precipitate qi, free milk, quiet fetus./Stomachache, diarrhea, water-damp fullness, inhibited urination, beriberi, jaundice, cough and qi counterflow, stirring fetus in pregnancy, edema in pregnancy, postpartum scant milk.
TCMBANKHE008659 Trifolium repens 三消草 To clear heat, cool blood, quiet heart./Epilepsy, bleeding from hemorrhoids, hard swelling.
TCMBANKHE008783 Hypericum chinense 金丝桃果实 To moisten lung and relieve cough./Lung disease, pertussis, vacuity heat cough.
TCMBANKHE006339 Brasenia schreberi To disinhibit water and disperse edema, clear heat and resolve toxin./Damp-heat dysentery, jaundice, edema, inhibited urination, heat toxin swollen welling abscess.
TCMBANKHE006690 Scolopendra subspinipes mutilans 蜈蚣 To calm, lower blood pressure, extinguish wind and check tetany, resolve toxin and dissipate binds, free network vessels and relieve pain./Acute fright wind, chronic fright wind, tetanus, spasm, convulsion, toxin swelling of sores and open sores, scrofula with ulceration, intractable headache with pulling sensation, wind-damp impediment pain, hypertension.
TCMBANKHE007186 Euonymus grandiflorus 野杜仲 To dispel wind and eliminate damp, quicken blood and free menstruation, transform stasis and dissipate binds./Lumbago, amenorrhea due to blood stasis, dysmenorrhea.
TCMBANKHE007625 Radix Solani melongee 茄根
TCMBANKHE008206 Musa paradisiaca var. sapientum [Syn. Musa sapientum] 香蕉 To clear heat, moisten lung, lubricate intestines, resolve toxin./Febrile diseases with vexation and thirst, lung heat dry cough, constipation, hemorrhoids.
TCMBANKHE006664/YNS-181/XU-60/XU-236 Fructus Arctii lappae|Arctium lappa L.|Arctium lappa 牛蒡子;大力子|牛蒡 牛蒡根 云南药材标准:第二册|西藏昌都市洛隆县 祛风清热,解毒消肿,力气通便。用于咽喉肿痛,牙龈肿痛,咳嗽痰稠,腹胀便秘,消渴;黄白带下,干血痨,产后少乳,风毒面肿,大头风,疮疡肿痛|To dispel wind-heat and relieve cough, to promote eruption, to counteract toxicity, and to soothe sore throat;Treament of cough and expectroation in influenza or upper respiratory infection, measles, rubella, sore throat, mumps, erysipelas, carbuncles and sores./Wind-heat common cold, cough with profuse phlegm, measles papules, wind papules, swelling pain in throat, epidemic parotitis;1. Its extract exerts a significant and prolonged effect of lowering blood sugar in rats.2. Mildly diuretic and laxative.3. An active component, arctiin, can induce tonic convulsion, feeble respiration and eventually paralysis in frogs, mice and rabbits. erysipelas, swollen welling abscess and sore toxin.
TCMBANKHE005418/YNS-102 Rhizoma Polygoni cuspidati|Polygonum cuspidatum Sieb.et Zucc. 虎杖 虎杖叶 云南药材标准:第一册 平肝潜阳,祛痰息风。用于肝阳上亢,血压偏高,头晕头昏|To dispel wind and damp, to eliminate blood stasis and alleviate pain, to relieve cough, and to resolve phlegm./Hyperlipemia, impediment pain in joints, damp-heat jaundice, toxic jaundice, child jaundice, amenorrhea, hepatitis, appendicitis, candida vaginitis, concretion and conglomeration, cough with profuse phlegm, burns and scalds, knocks and falls, swelling toxin of welling abscess and sore.
TCMBANKHE004273/YEM-411 Solanum melongena|Solanum melongena L. 茄叶|茄 茄子 云南民族药物志:第二卷 To dissipate blood and disperse swelling./Blood strangury, blood dysentery, intestinal wind bleeding, swollen welling abscess, frostbite. 傣族/德昂族/基诺族/佤族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000060 CRHR1 CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1L corticotropin releasing hormone receptor 1
TCMBANKGE000192 CDH5 7B4; CD144 cadherin 5
TCMBANKGE000326 SELP CD62; CD62P; GMP140; GRMP; LECAM3; PADGEM; PSEL selectin P
TCMBANKGE001069 MPO - myeloperoxidase
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001118 MMP9 CLG4B; GELB; MANDP2; MMP-9 matrix metallopeptidase 9
TCMBANKGE001816 HRH1 H1-R; H1R; HH1R; hisH1 histamine receptor H1
TCMBANKGE003646 HRH2 H2R; HH2R histamine receptor H2
TCMBANKGE006886 ADH1A ADH1 alcohol dehydrogenase 1A (class I), alpha polypeptide
TCMBANKGE008278 COL4A4 ATS2; BFH; CA44 collagen type IV alpha 4 chain
TCMBANKGE008658 DEFB104A BD-4; DEFB-4; DEFB104; DEFB4; hBD-4 defensin beta 104A
TCMBANKGE008718 PRSS3 MTG; PRSS4; T9; TRY3; TRY4 serine protease 3
TCMBANKGE009389 LYZ LYZF1; LZM lysozyme
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1