Compound Summary


  Compound Information

药名:

Yamogenin

别名:

WQLVFSAGQJTQCK-CAKNJAFZSA-N; (25S)-spirost-5-en-3beta-ol; NSC 226132; LMST01080045; AC1L9BVW; AC-8895; S00020; (2R,5'S)-5'-tetramethylspiro[[?]-2,2'-tetrahydropyran]ol; Jamogenin; Neodiosgenin; AKOS025402417; CHEBI:10086; Spirost-5-en-3-ol, (3beta,25S)-; SCHEMBL6040875; CHEMBL400807; C08918; yamogenin; ZINC8234229; 512-06-1; 25-epi-Diosgenin

分子式:

C27H42O3

Smiles:

CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)O)C)C)C)OC1

成分:

HBIN048582

OB_score:

17.194518

CAS_id:

512-06-1

SymMap_id:

SMIT05891;SMIT18261

TCMID_id:

22862

TCMSP_id:

MOL003885

PubChem_id:

138108501


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000698 Radix Asparagi 天冬 To replenish yin, promote fluid secretion and moisten the lung./1. Asparamide is an expectorant, antitussive and antiasthmatic.2. Inhibiting the cell growth of acute lymphocytic, acute monocytic and chronic granulocytic leukemias in vitro.
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE003028 粉萆薢 Treatment of chyluria, turbid urine mixed with whitish substance or whitish discharge from urethra, excessive leukorrhea, rheumatic arthralgia with limitation of motion and pain in the loins and knees.
TCMBANKHE003878 Folium Mahoe 十大功劳叶 Tuberculosis and hemoptysis, steaming bone tidal fever, dizziness and tinnitus, limp aching lumbus and knees, damp-heat jaundice, vaginal discharge, dysentery, wind-heat common cold, red eyes with gall, swollen welling abscess and sores.
TCMBANKHE008332 绵萆薢 Strangury with white turbidity, excessive leukorrhea, damp-heat sore toxin, impediment pain in lumbus and knees.
TCMBANKHE005809 Dioscorea parviflora 小花盾叶薯蓣 To clear heat and resolve toxin, quicken blood and disperse swelling./Swelling toxin of welling abscess and boil, soft tissue sprain, bee sting, insect bites.
TCMBANKHE004539 Fructus Kochiae 地肤子 To remove damp-heat, to dispel zvind, and to relieve itching./Inhibiting the growth of various dermatomyces in vitro.
TCMBANKHE004858 白毛藤 Malaria, jaundice, edema, strangury, pain in joints due to rheumatalgia, erysipelas, clove sore.
TCMBANKHE006165 Rhizoma Dioscoreae bulbiferae 黄药子 To remove phlegm, disperse the lumps, detoxify and relieve swelling. /Goiter and tuberculosis, throat impediment, swelling toxin of welling abscess and sore, poisonous snake bite, carcinoma, blood ejection, spontaneous external bleeding, hemoptysis, pertussis, lung heat cough.
TCMBANKHE008402 Dioscorea gracillima 纤细薯蓣 See Dioscorea hypoglauca./See Dioscorea hypoglauca.
TCMBANKHE008433 Dioscorea tokoro 山萆薢 See Dioscorea hypoglauca./See Dioscorea hypoglauca.
TCMBANKHE007038 Solanum dulcamara 千年不烂心 To expel wind and eliminate damp, clear heat and resolve toxin./Wind-damp pain, tetanus, swollen welling abscess, malign sore, scab sore, bleeding due to external injury.
TCMBANKHE007606 菝葜 Wind-damp impediment pain, strangury-turbidity, vaginal discharge, dysentery, diarrhea, swelling toxin of welling abscess and sore, intractable lichen, burns and scalds.
TCMBANKHE007734 Fructus Tribuli 蒺藜 To subdue hyperactivity of the liver, to promote blood circulation, to dispel wind, to clear the eye of opacity, and to arrest itching./1. Antitussive, expectorant and antiasthmatic. 2. Its alcoholic infusion exerts hypotensive effect in anesthetized animals.
TCMBANKHE003914/YEM-562 Dioscorea collettii|Dioscorea collettii Hook.f. 叉蕊薯蓣 叉蕊薯蓣 云南民族药物志:第三卷 To dispel wind and disinhibit damp, free network vessels and relieve pain, clear heat and resolve toxin./Wind-damp impediment pain, hypertonicity and numbness, qi stagnation stomachache, damp-heat jaundice, white turbidity, strangury with pain, leukorrhea, knocks and falls, damp sore with swelling toxin, wind papules, eczema, poisonous snake bite. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE007349/YEM-562 Dioscorea hypoglauca [Syn. Dioscorea collettii var. hypoglauca]|Dioscorea collettii Hook.f. 萆薢|叉蕊薯蓣 叉蕊薯蓣 云南民族药物志:第三卷 To disinhibit damp and turbidity, dispel wind-damp./Unctuous strangury, white turbidity, vaginal discharge, sores, wind-damp impediment pain. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE004138/YEM-734/XU-660 Fructus Bruceae|Brucea javanica(L.)Merr.|Brucea javanica 鸦胆子 鸦胆子 云南民族药物志:第四卷|云南省文山州富宁县 To remove toxic heat, to stop malarial attacks, to relieve dysentery, and to cauterize vegetations./Malaria, amebic dysentery, dysentery with pus and blood, tenesmus, corn and common wart. 阿昌族/傣族/德昂族/基诺族/景颇族/傈僳族/彝族/壮族
TCMBANKHE007758/YEM-743 Rhizoma Polygoti Odorati|Polygonatum odoratum(Mill.)Druce 玉竹 玉竹 云南民族药物志:第四卷 To nourish yin, promote the production of body fluid, and relieve dryness syndromes./Lung stomach yin damage, dry cough, dry throat, diabetes mellitus due to internal heat. 哈尼族/傈僳族/瑶族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000168 NR3C1 GCCR; GCR; GCRST; GR; GRL nuclear receptor subfamily 3 group C member 1
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000737 PGR NR3C3; PR progesterone receptor
TCMBANKGE002388 NR3C2 MCR; MLR; MR; NR3C2VIT nuclear receptor subfamily 3 group C member 2
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor