Compound Summary


  Compound Information

药名:

Tylophorinidine

别名:

32523-69-6; tylophorinidine; 36614-30-9; Dibenzo(f,h)pyrrolo(1,2-b)isoquinoline-6,14-diol, 9,11,12,13,13a,14-hexahydro-3,7-dimethoxy-, (13aS-trans)-

分子式:

C22H23NO4

Smiles:

COC1=CC2=C(C=C1)C3=C(CN4CCCC4C3O)C5=CC(=C(C=C52)O)OC

成分:

HBIN047424

OB_score:

30.482459

CAS_id:

32523-69-6

SymMap_id:

SMIT13651

TCMID_id:

22136

TCMSP_id:

MOL012933

PubChem_id:

161749


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003417 Ficus septica
TCMBANKHE005951 Tylophora crebriflora 密花娃儿藤
TCMBANKHE004521 Vincetoxicum officinale [Syn. Cynanchum vincetoxicum] 药用白前
TCMBANKHE004955 Tylophora atrofolliculata 三分丹 To dispel wind, quicken blood, relieve pain./Wind-damp pain, painful swelling from knocks and falls.
TCMBANKHE005321 Tylophora asthmatica [Syn. Tylophora indica ] 印度娃儿藤
TCMBANKHE008557 Tylophora atrofolliculata 三分丹 To dispel wind, quicken blood, relieve pain./Wind-damp pain, painful swelling from knocks and falls.
TCMBANKHE006481 Tylophora floribunda 娃儿藤 To dispel wind and transform phlegm, quicken blood and relieve pain, resolve toxin and disperse swelling./Infant fright wind, wind-damp impediment pain, cough and asthma with abundant phlegm, diphtheria, knocks and falls, fracture, poisonous snake bite, swollen welling abscess, sore and boil, red eyes, stomatitis, liver spleen enlargement.
TCMBANKHE006716 Tylophora mollissima 绵毛娃儿藤 To clear lung heat, relieve cough and asthma./Common cold with fever, lung heat cough, asthma.
TCMBANKHE008835 Rhizoma cynchi stauntonii 白前 1. To resolve phlegm and stop cough; 2. To conduct qi downward/1. Treatmant of cough due to invasion by exogenous pathogenic factors. Swallowwort rhizome (Baiqian) is used with Schizonepeta (Jingjie) and Platycodon root (Jiegeng) in the formula Zhisuo San. 2. Treatment of turbid phlegm blocking the lungs
TCMBANKHE005201/YEM-6/YEM-114/XU-81/XU-363 Tylophora ovata|Gerbera piloselloides (L.) Cass.|Cynanchum atratum 卵叶娃儿藤|毛大丁草|白薇 毛丁白头翁 云南民族药物志:第一卷|云南省曲靖市会泽县 To clear heat and boost yin, disinhibit urine and free strangury, resolve toxin and cure sores./Warm heat disease with fever, generalized fever with macule, steaming bone tidal fever, lung heat cough, postpartum vacuity vexation, heat strangury, blood strangury, swelling pain in throat, swelling toxin of sore and welling abscess, poisonous snake bite. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001657 PDF - peptide deformylase, mitochondrial
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1