Compound Summary

  Compound Information

TCMBANKIN009747

药名:	stepharine
别名:	AC1LH1T2; Stepharine; ZINC26787150; CHEMBL463957
分子式:	C18H19NO3
Smiles:	COC1=C(C2=C3C(CC24C=CC(=O)C=C4)NCCC3=C1)OC
成分:	HBIN044797
OB_score:	31.547867
CAS_id:	2810-21-1
SymMap_id:	SMIT00326
TCMID_id:	20306
TCMSP_id:	MOL012921
PubChem_id:	98455

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE001634	Fructus Choerospondiatis	广枣			To promote the flow of qi and blood, to replenish the heart and allay excitement./Treatment of stagnation of qi and blood with pectoral pain, palpitation and shortness of breath, uneasiness in mind.
TCMBANKHE003066	Artabotrys uncinatus
TCMBANKHE007156	Herba Patriniae	败酱草			1. To eliminate heat and toxic material, relieve abscess and promote pus drainage. 2. To remove blood stasis and alleviate pain/1. Two active components, patrinene and isopatrinene, possess sedative effect. 2. To promote regeneration of hepatic cells and portal circulation, protect hepatic cells from degernation and improve hepatic function.
TCMBANKHE004121	Radix Stemoe	百部			1. To moisten the lungs and stop cough; 2. To kill lice and parasites/Wind-cold cough, pertussis, tuberculosis, senile cough and asthma, ascariasis, oxyuria disease, scab and lichen, eczema, cootie.
TCMBANKHE006056	Rhizoma Menispermi	北豆根			To remove toxic heat and relieve rheumatic pains./Treatment of sore throat, colitis, dysentery, rheumatic arthralgia.
TCMBANKHE004636	Fructus Zizyphi Jujubae	大枣			To tonify the spleen and replenish qi, to nourish blood, and to ease the mind./Reduced food intake due to spleen vacuity, lack of strength and sloppy stool, visceral agitation.
TCMBANKHE009013	Cortex Illicii	地枫皮			To relieve rheumatic conditions, and to promote the flow of qi and relieve pain./Pain in joints due to rheumatalgia, taxation damage in lumbar muscle, centipede bite.
TCMBANKHE007730	Fructus Meliae Toosendan	川楝子			To relieve pain by smoothing the flow of the liver qi and to repel worms./Chest and rib-side pain, distending pain in stomach duct, mounting qi , abdominal pain due to worm accumulation.
TCMBANKHE008341	Fructus Zizyphi Jujubae	大枣			To tonify the spleen and replenish qi, to nourish blood, and to ease the mind./Reduced food intake due to spleen vacuity, lack of strength and sloppy stool, visceral agitation.
TCMBANKHE006940	Herba Potentillae Discoloris	翻白草			1. To clear away heat and toxic material. 2. To cool the blood and stop bleeding./Cough and asthma due to lung heat, diarrhea dysentery, malaria, hacking of blood, blood ejection, bloody stool, flooding and spotting [=metrorrhagia and metrostaxis], swelling toxin of welling abscess and sore, scrofula.
TCMBANKHE006714	Folium Clerodentri trichotomi	臭梧桐			To dispel wind and dampness/Hypertension, malaria, wind-damp impediment, numbness in limbs, hemiplegia, migraine, dysentery, hemorrhoids, welling abscess and flat abscess, scab sore.
TCMBANKHE007238	Radix Stephaniae Tetrandrae	防己			To cause diuresis and to relieve rheumatic conditions./Beriberi with edema, inhibited urination, eczema, sore toxin, wind-damp impediment pain, hypertension, adjuvant in anesthesia.
TCMBANKHE007462		青风藤			Wind-damp impediment pain, pain from arthritis, swelling in joints, paralytic and pruritus.
TCMBANKHE007889		杜仲叶			Lumbar and back pain, limp aching inability of legs and knees, hypertension.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000425	DRD1	DADR; DRD1A	dopamine receptor D1
TCMBANKGE000633	ADRB2	ADRB2R; ADRBR; B2AR; BAR; BETA2AR	adrenoceptor beta 2
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000766	ACHE	ACEE; ARACHE; N-ACHE; YT	acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000869	DRD2	D2DR; D2R	dopamine receptor D2
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000965	CHRNA7	CHRNA7-2; NACHRA7	cholinergic receptor nicotinic alpha 7 subunit
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001506	ADRA1B	ADRA1; ALPHA1BAR	adrenoceptor alpha 1B
TCMBANKGE001943	ADRA1D	ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2	adrenoceptor alpha 1D
TCMBANKGE003157	CHRM2	HM2	cholinergic receptor muscarinic 2
TCMBANKGE003625	SLC6A4	5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT	solute carrier family 6 member 4
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE005535	CHRM1	HM1; M1; M1R	cholinergic receptor muscarinic 1
TCMBANKGE006943	CHRM3	EGBRS; HM3; PBS	cholinergic receptor muscarinic 3
TCMBANKGE008124	ADRA2B	ADRA2L1; ADRA2RL1; ADRARL1; ALPHA2BAR; FAME2; alpha-2BAR	adrenoceptor alpha 2B
TCMBANKGE008700	CHRNA2	-	cholinergic receptor nicotinic alpha 2 subunit
TCMBANKGE008702	OPRM1	LMOR; M-OR-1; MOP; MOR; MOR1; OPRM	opioid receptor mu 1
TCMBANKGE008921	RXRA	NR2B1	retinoid X receptor alpha
TCMBANKGE009256	SLC6A2	NAT1; NET; NET1; SLC6A5	solute carrier family 6 member 2
TCMBANKGE009294	HTR3A	5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3	5-hydroxytryptamine receptor 3A
TCMBANKGE009455	CHRM5	HM5	cholinergic receptor muscarinic 5
TCMBANKGE011923	CHRM4	HM4; M4R	cholinergic receptor muscarinic 4
TCMBANKGE012155	SLC6A3	DAT; DAT1; PKDYS; PKDYS1	solute carrier family 6 member 3
TCMBANKGE013826	DRD5	DBDR; DRD1B; DRD1L2	dopamine receptor D5
TCMBANKGE014050	GABRA1	ECA4; EIEE19; EJM; EJM5	gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014423	ADRA1A	ADRA1C; ADRA1L1; ALPHA1AAR	adrenoceptor alpha 1A
TCMBANKGE014625	OPRD1	DOP; DOR; DOR1; OPRD	opioid receptor delta 1