Compound Summary


  Compound Information

药名:

monocrotaline

分子式:

C16H23NO6

Smiles:

CC1C(=O)OC2CCN3C2C(=CC3)COC(=O)C(C1(C)O)(C)O

成分:

HBIN035672

SymMap_id:

SMIT16753

TCMID_id:

14915

PubChem_id:

9415


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000027 Crotalaria stipularia
TCMBANKHE000313 Herba Crotalariae 农吉利 For carcinoma of skin and cervix./1. Monocrotaline is an anticarcinogenic component which inhibits the synthesis of DNA and RNA. 2. Its extract relieves cough and dyspnea. 3. The metabolite of monocrotaline in liver has the toxic effect similar to alkylating agents, which impairs the digestive tract, liver, kidney and hematopoietic system.
TCMBANKHE001405 凹叶野百合
TCMBANKHE001523 Crotalaria quinquefolia 午夜猪屎豆
TCMBANKHE001657 Crotalaria crispata
TCMBANKHE001777 Rhizoma Dioscoreae Nipponicae 穿山龙 1. To promote blood circulation and dredge the channels. 2. To expel wind and dampness. 3. To eliminate phlegm, and relieve cough and dyspnea. 4. To clear toxic materials and relieve swelling./1. Its saponins are antitussives and expectorants.2. Its decoction can relax histamine- or acetylcholine-induced bronchial spasm in guinea-pigs.3. Decreasing cholesterol level, slowing heart rate and increasing coronary flow.4. Anti-allergic.
TCMBANKHE004191 Crotalaria nana 小猪屎豆
TCMBANKHE004651 Medulla Junci 灯心草 To eliminate excess fire in the heart, and to induce diuresis./Strangury, edema, inhibited urination, damp-heat jaundice, insomnia and vexation, infant night crying, throat impediment, mouth sore, wound.
TCMBANKHE005624 Crotalaria sessiliflora 野百合 To clear heat, resolve toxin, disinhibit damp, disperse accumulation./Dysentery, heat strangury, cough and asthma, wind-damp impediment pain, clove sore and swollen boil, poisonous snake bite, child gan accumulation, carcinoma of uterine cervix, carcinoma of esophagus, carcinoma of lung, carcinoma of liver, carcinoma of stomach, squamous carcinoma of skin.
TCMBANKHE007370 Crotalaria spectabilis 美丽猪屎豆
TCMBANKHE008321 Crotalaria retusa 澳洲屎豆
TCMBANKHE000311/YNS-35/YEM-652/XU-153 Crotalaria assamica Benth.|Crotalaria assamica 自消容|大猪屎豆 大狗响铃|大猪屎豆 云南药材标准:第五册|云南民族药物志:第四卷|贵州省贵阳市花溪区党武镇 清热凉血,利水解毒,消肿止痛,用于发热咳嗽、咯血,久咳,牙痛,胆汁病(黄疸病,白疸病,黑疸病),水肿,六淋证(脓尿,血尿,尿血,沙尿,石尿,白尿)风湿痹痛,跌打损伤,淤肿疼痛,疔疮痈疖, 基诺族/佤族/瑶族/壮族
TCMBANKHE003689/YNS-35/YEM-652/XU-153 Crotalaria assamica Benth.|Crotalaria assamica 自消容根|大猪屎豆 大狗响铃|大猪屎豆 云南药材标准:第五册|云南民族药物志:第四卷|贵州省贵阳市花溪区党武镇 清热凉血,利水解毒,消肿止痛,用于发热咳嗽、咯血,久咳,牙痛,胆汁病(黄疸病,白疸病,黑疸病),水肿,六淋证(脓尿,血尿,尿血,沙尿,石尿,白尿)风湿痹痛,跌打损伤,淤肿疼痛,疔疮痈疖, 基诺族/佤族/瑶族/壮族
TCMBANKHE006350/YNS-35/YEM-652/XU-153 Crotalaria assamica|Crotalaria assamica Benth. 自消容子|大猪屎豆 大狗响铃|大猪屎豆 云南药材标准:第五册|云南民族药物志:第四卷|贵州省贵阳市花溪区党武镇 清热凉血,利水解毒,消肿止痛,用于发热咳嗽、咯血,久咳,牙痛,胆汁病(黄疸病,白疸病,黑疸病),水肿,六淋证(脓尿,血尿,尿血,沙尿,石尿,白尿)风湿痹痛,跌打损伤,淤肿疼痛,疔疮痈疖,|To dispel wind and eliminate damp, stanch bleeding and disperse swelling, kill worms./Wind-damp bone pain, knocks and falls, bleeding due to external injury, child gan accumulation. 基诺族/佤族/瑶族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000330 HMOX1 HMOX1D; HO-1; HSP32; bK286B10 heme oxygenase 1
TCMBANKGE000713 CCN2 CTGF; HCS24; IGFBP8; NOV2 cellular communication network factor 2
TCMBANKGE001037 MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 matrix metallopeptidase 2
TCMBANKGE001097 HIF1A HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 hypoxia inducible factor 1 subunit alpha
TCMBANKGE001118 MMP9 CLG4B; GELB; MANDP2; MMP-9 matrix metallopeptidase 9
TCMBANKGE001181 TGFB1 CED; DPD1; IBDIMDE; LAP; TGF-beta1; TGFB; TGFbeta transforming growth factor beta 1
TCMBANKGE001522 ALAS2 ALAS-E; ALASE; ANH1; ASB; SIDBA1; XLDPP; XLEPP; XLSA 5'-aminolevulinate synthase 2
TCMBANKGE003245 PDGFB IBGC5; PDGF-2; PDGF2; SIS; SSV; c-sis platelet derived growth factor subunit B
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE008786 CRAT CAT; CAT1; NBIA8 carnitine O-acetyltransferase
TCMBANKGE014899 TRIOBP DFNB28; HRIHFB2122; TAP68; TARA; dJ37E16.4 TRIO and F-actin binding protein