Compound Summary

  Compound Information

TCMBANKIN010818

药名:	N-Methylflindersine
别名:	2,2,6-Trimethyl-2H,5H-pyrano[3,2-c]quinolin-5-one; NSC347659; MolPort-039-338-565; CHEMBL400130; SMR001874966; 2,2,6-trimethylpyrano[5,6-c]quinolin-5-one; 5H-Pyrano[3,2-c]quinolin-5-one, 2,6-dihydro-2,2,6-trimethyl-; AKOS028108463; 5H-Pyrano(3,2-c)quinolin-5-one, 2,6-dihydro-2,2,6-trimethyl-; 4CN-2980; 2,2,6-Trimethyl-2H,5H-pyrano(3,2-c)quinolin-5-one; 2,2,6-trimethyl-5-pyrano[5,6-c]quinolinone; 2,6-Dihydro-2,2,6-trimethyl-5H-pyrano(3,2-c)quinolin-5-one; AC1L2IQN; 2,2,6-trimethylpyrano[3,2-c]quinolin-5-one; C10731; ZINC900263; NSC-347659; NSC 347659; AC1Q2CW2; MLS003171057; CTK4J2456; n-methylflindersine; RJZFGBNKPOVCHQ-UHFFFAOYSA-N; 2,2,6-Trimethyl-2,6-dihydro-5H-pyrano[3,2-c]quinolin-5-one #; CHEBI:7315; DTXSID40198374; 50333-13-6
分子式:	C15H15NO2
Smiles:	CC1(C=CC2=C(O1)C3=CC=CC=C3N(C2=O)C)C
成分:	HBIN037087
OB_score:	32.357876
CAS_id:	50333-13-6
SymMap_id:	SMIT04593;SMIT16623
TCMID_id:	14439
TCMSP_id:	MOL002331
PubChem_id:	72819

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003021		关黄柏
TCMBANKHE003847	Ptelea trifoliata	渝橘
TCMBANKHE004741	Orixa japonica	臭山羊			To clear heat and resolve exterior, move qi and relieve pain, dispel wind and disinhibit damp./Wind-heat common cold, cough, throat pain, toothache, stomachache, pain in joints due to rheumatalgia, dysentery, innominate toxin swelling.
TCMBANKHE009013	Cortex Illicii	地枫皮			To relieve rheumatic conditions, and to promote the flow of qi and relieve pain./Pain in joints due to rheumatalgia, taxation damage in lumbar muscle, centipede bite.
TCMBANKHE007238	Radix Stephaniae Tetrandrae	防己			To cause diuresis and to relieve rheumatic conditions./Beriberi with edema, inhibited urination, eczema, sore toxin, wind-damp impediment pain, hypertension, adjuvant in anesthesia.
TCMBANKHE004238/YEM-1014	Phellodendron amurense;Cortex Phellodendri|Phellodendron chinense Schneid var.glabriusculum Schneid.	黄柏|秃叶黄蘗	广西黄柏	云南民族药物志：第五卷	1. To clear heat and dry dampness; 2. To reduce fire and release toxins/Damp-heat dysentery, tuberculosis, epidemic meningitis, acute conjunctivitis, trachoma, fever, abdominal pain, diarrhea, suppurative hematochezia, tenesmus, jaundice, yellow thick foul leukorrhagia, swelling pain in knees and feet, urinary tract infection, boil, sore, ulcer, eczema, mouth sore, hemorrhoids, burns, scalds, exuberance of fire with tidal fever, tidal fever with night sweat, emission.	瑶族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000425	DRD1	DADR; DRD1A	dopamine receptor D1
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000633	ADRB2	ADRB2R; ADRBR; B2AR; BAR; BETA2AR	adrenoceptor beta 2
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE000965	CHRNA7	CHRNA7-2; NACHRA7	cholinergic receptor nicotinic alpha 7 subunit
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001506	ADRA1B	ADRA1; ALPHA1BAR	adrenoceptor alpha 1B
TCMBANKGE001943	ADRA1D	ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2	adrenoceptor alpha 1D
TCMBANKGE003157	CHRM2	HM2	cholinergic receptor muscarinic 2
TCMBANKGE003625	SLC6A4	5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT	solute carrier family 6 member 4
TCMBANKGE005535	CHRM1	HM1; M1; M1R	cholinergic receptor muscarinic 1
TCMBANKGE006943	CHRM3	EGBRS; HM3; PBS	cholinergic receptor muscarinic 3
TCMBANKGE008921	RXRA	NR2B1	retinoid X receptor alpha
TCMBANKGE009256	SLC6A2	NAT1; NET; NET1; SLC6A5	solute carrier family 6 member 2
TCMBANKGE009455	CHRM5	HM5	cholinergic receptor muscarinic 5
TCMBANKGE009758	PDE3A	CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB	phosphodiesterase 3A
TCMBANKGE011923	CHRM4	HM4; M4R	cholinergic receptor muscarinic 4
TCMBANKGE012155	SLC6A3	DAT; DAT1; PKDYS; PKDYS1	solute carrier family 6 member 3
TCMBANKGE014050	GABRA1	ECA4; EIEE19; EJM; EJM5	gamma-aminobutyric acid type A receptor subunit alpha1