Compound Summary

  Compound Information

TCMBANKIN011656

药名:	toddaline
别名:	chelerythrine; toddaline
分子式:	C21H18NO4+
Smiles:	C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5
成分:	HBIN046512
OB_score:	25.990223
CAS_id:	34316-15-9
SymMap_id:	SMIT03886
TCMSP_id:	MOL001478
PubChem_id:	2703

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000810	Radix Zanthoxyli	两面针			To promote the flow of qi, relieve pain, to eliminate blood stasis, to promote blood circulation and dispel wind./Treatment of traumatic injury, rheumatic arthralgia, stomach-ache, teethache, bitten by venomous snake, applied for burn caused by hot liquid or fire.
TCMBANKHE006371		白屈菜			Pain in sensory nerve endings, pain from ulcer in digestive tract, stomachache, abdominal pain, enteritis, dysentery, chronic bronchitis, pertussis, cough, jaundice, edema, ascites, scab and lichen with swelling of sores, snake or insect bites.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000051	IL1B	IL-1; IL1-BETA; IL1F2; IL1beta	interleukin 1 beta
TCMBANKGE000121	KCNH2	ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1	potassium voltage-gated channel subfamily H member 2
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000197	KCNJ11	BIR; HHF2; IKATP; KIR6.2; MODY13; PHHI; PNDM2; TNDM3	potassium inwardly rectifying channel subfamily J member 11
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000222	EDN1	ARCND3; ET1; HDLCQ7; PPET1; QME	endothelin 1
TCMBANKGE000224	AGT	ANHU; SERPINA8; hFLT1	angiotensinogen
TCMBANKGE000330	HMOX1	HMOX1D; HO-1; HSP32; bK286B10	heme oxygenase 1
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000637	SDHB	CWS2; IP; PGL4; SDH; SDH1; SDH2; SDHIP	succinate dehydrogenase complex iron sulfur subunit B
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000766	ACHE	ACEE; ARACHE; N-ACHE; YT	acetylcholinesterase (Cartwright blood group)
TCMBANKGE000785	G6PD	G6PD1	glucose-6-phosphate dehydrogenase
TCMBANKGE000859	PRKCD	ALPS3; CVID9; MAY1; PKCD; nPKC-delta	protein kinase C delta
TCMBANKGE000866	PRKCB	PKC-beta; PKCB; PKCI(2); PKCbeta; PRKCB1; PRKCB2	protein kinase C beta
TCMBANKGE000898	MYC	MRTL; MYCC; bHLHe39; c-Myc	MYC proto-oncogene, bHLH transcription factor
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000994	AKR1B1	ADR; ALDR1; ALR2; AR	aldo-keto reductase family 1 member B
TCMBANKGE001068	CXCL1	FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1	C-X-C motif chemokine ligand 1
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001079	CYP1A1	AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX	cytochrome P450 family 1 subfamily A member 1
TCMBANKGE001097	HIF1A	HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78	hypoxia inducible factor 1 subunit alpha
TCMBANKGE001148	VEGFA	MVCD1; VEGF; VPF	vascular endothelial growth factor A
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001171	SRC	ASV; SRC1; THC6; c-SRC; p60-Src	SRC proto-oncogene, non-receptor tyrosine kinase
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE001203	MAPK1	ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK	mitogen-activated protein kinase 1
TCMBANKGE001210	NPY6R	NPY1RL; NPY6RP; PP2; Y2B	neuropeptide Y receptor Y6 (pseudogene)
TCMBANKGE002155	SLC17A8	DFNA25; VGLUT3	solute carrier family 17 member 8
TCMBANKGE002243	SLC9A3	DIAR8; NHE-3; NHE3	solute carrier family 9 member A3
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE005653	GRIN2A	EPND; FESD; GluN2A; LKS; NMDAR2A; NR2A	glutamate ionotropic receptor NMDA type subunit 2A
TCMBANKGE006713	SLC1A7	AAAT; EAAT5	solute carrier family 1 member 7
TCMBANKGE007855	FCAMR	CD351; FCA/MR; FKSG87	Fc fragment of IgA and IgM receptor
TCMBANKGE008240	MSH2	COCA1; FCC1; HNPCC; HNPCC1; LCFS2; hMSH2	mutS homolog 2
TCMBANKGE008921	RXRA	NR2B1	retinoid X receptor alpha
TCMBANKGE009939	SLC1A6	EAAT4	solute carrier family 1 member 6
TCMBANKGE010424	CTNNBIP1	ICAT	catenin beta interacting protein 1
TCMBANKGE010461	MSH6	GTBP; GTMBP; HNPCC5; HSAP; p160	mutS homolog 6
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE012736	CA9	CAIX; MN	carbonic anhydrase 9
TCMBANKGE013520	NPPC	CNP; CNP2	natriuretic peptide C