Compound Summary

  Compound Information

TCMBANKIN012460

化合物待补充

药名:	Folinic acid
别名:	4-{[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methyl]amino}-N-(1,3-dicobaltiopropyl)benzamide; folinic acid; N5 -Formyl-5,6,7,8- tetrahydropteroyl-L -glutamic acid; N5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid; folinicacid
分子式:	C99H148N24O24S2
Smiles:	C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Ca+2]
成分:	HBIN026629
OB_score:	23.600435
CAS_id:	21314
SymMap_id:	SMIT05858;SMIT15404;SMIT19188
TCMID_id:	30968;7852
TCMSP_id:	MOL003845
PubChem_id:	135802074

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000232		川射干
TCMBANKHE004260	Radix Ginseng	人参			To reinforce the vital energy, to remedy collapse and restore the normal pulse, to benefit the spleen and lung, to promote the production of body fluid, and to calm the nerves./Qi vacuity and verging on desertion, cold limbs and faint pulse, reduced food intake due to spleen vacuity, cough and asthma due to lung vacuity, fluid damage and thirst, diabetes mellitus due to internal heat, enduring illness qi vacuity, fright palpitation and insomnia, impotence, uterus cold, cardiac failure.
TCMBANKHE001634	Fructus Choerospondiatis	广枣			To promote the flow of qi and blood, to replenish the heart and allay excitement./Treatment of stagnation of qi and blood with pectoral pain, palpitation and shortness of breath, uneasiness in mind.
TCMBANKHE003063	Herba Plantaginis	车前草			To remove heat and to induce diureses, to promote expectoration, to reduce heat in blood and to counteract toxicity./Treatment of edema with oliguria, urinary infection with difficult painful urination, diarrhea caused by summer-damp, cough caused by phlegm-heat, spitting of blood, epistaxis, carbuncles and sores.
TCMBANKHE003742	Agaricus campestris	蘑菇			To fortify spleen and promote digestion, calm liver and raise spirit./Non-digestion of food accumulation, torpid intake, scant breast milk, hypertension, fatigued spirit and desire to sleep.
TCMBANKHE003743	Radix Astragali	黄芪			To reinoforce qi and invigorate the function of the spleen./Common cold, influenza, chronic wound ulcer, chronic glomerulonephritis, diabetes mellitus due to internal heat, qi vacuity edema, chronic gastritis, qi vacuity and hypodynamia, reduced food intake and sloppy stool, center qi fall, chronic diarrhea, prolapse of rectum, hematochezia, flooding and spotting, spontaneous sweating due to exterior vacuity.
TCMBANKHE005370	Bos taurus domesticus, Bubalus bubalis	牛乳			To supplement vacuity detriment, boost lung and stomach, nourish blood, engender liquid and moisten dryness, resolve toxin./Vacuity taxation detriment, stomach reflux and dysphagia-occlusion, diabetes mellitus, anemia and constipation, qi vacuity and dysentery, jaundice.
TCMBANKHE003939	Spinacia oleracea	菠菜			To nourish blood, stanch bleeding, calm liver, moisten dryness./Spontaneous external bleeding, hematochezia, headache, dizziness and dim vision, red eyes, night blindness, diabetes mellitus, fecal stoppage, hemorrhoids.
TCMBANKHE004247	Angelica acutiloba [Syn. Ligusticum acutilobum]	东当归			To supplement blood and quicken blood, regulate menstruation and relieve pain, moisten dryness and lubricate intestines./Blood vaculty, menstrual disorder, dysmenorrhea, amenorrhea, postpartum abdominal pain, intestinal dry and constipation.
TCMBANKHE004258	Radix Angelicae sinensis	当归根			To enrich blood, activate blood circulation, regulate menstruation, relieve pain, and relax bowels./Women’s diseases, blood deficiency syndrome, menstrual disorder, amenorrhea and dysmenorrhea, dysmenorrhea due to anemia, thrombophlebitis, neuralgia, arthritis, chronic nephritis, constrictive aortitis, blood vaculty, pernicious anemia, anemia due to folic acid deficiency, dysentery, hepatitis, Raynaud’s disease, lumbago, various pains due to blood stasis and rheumatic impediment, sores, welling abscess, constipation, ulcer in gastrointestinal tract, skin diseases, eczema, dermatitis, neurodermatitis, psoriasis.
TCMBANKHE004523	Flos Gossampini	木棉花			Diarrhea, dysentery, hemoptysis, blood ejection, flooding, incised wound and bleeding, sore toxin, eczema.
TCMBANKHE004852	Apis cerana	蜂乳			To enrich and supplement, enrich and invigorate, boost liver, fortify spleen./Weakness during convalescence, gan accumulation, senile vacuity weakness, septicemia, chronic hepatitis, duodenal ulcer, rheumatic arthritis, hypertension, diabetes mellitus, dysfunctional uterine bleeding, infertility.
TCMBANKHE007981	Trifolium pratense	红车轴草			To clear heat and relieve cough, dissipate binds and disperse swelling./Common cold, cough and asthma, hard swelling, burns.
TCMBANKHE005222	Apis cerana	蜂蜜			To supplement stomach and spleen, relax tension and relieve pain, moisten lung and relieve cough, moisten intestines and free stool, moisten skin and engender flesh, resolve toxin./Pain in stomach duct and abdomen, lung heat dry cough, intestinal dry and constipation, red eyes, mouth sore, enduring sores, wind papule itching, burns and scalds, cracking of hands and feet.
TCMBANKHE006021	Semen Sesami Nigrum	黑芝麻			To tonify the liver and the kidney, to replenish vital essence and blood, and to relax the bowels./Dizziness, tinnitus and deafness, premature graying in beard and hair, hair loss during convalescence, intestinal dry and constipation.
TCMBANKHE006022	Angelica acutiloba var. sugiyamae	北海当归
TCMBANKHE006054	Radix chuanxiong;Rhizoma Chuanxiong	川芎			1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE004944/XU-432	Taraxacum officinale	药用蒲公英		湖北省恩施州板桥镇
TCMBANKHE007505	Malus asiatica	林檎			To precipitate qi and loosen chest, engender liquid and allay thirst, harmonize center and relieve pain./Diabetes mellitus, phlegm-rheum and food retention, glomus and congestion in chest and diaphragm, cholera, vomiting diarrhea with abdominal pain, dysentery.
TCMBANKHE006949	Hippophae rhamnoides	醋柳果			To relieve cough and transform phlegm, fortify stomach and disperse food, quicken blood and dissipate stasis./Cough with profuse phlegm, pulmonary welling abscess, indigestion, food accumulati on abdominal pain, stomachache, enteritis, amenorrhea, stasis swelling from knocks and falls.
TCMBANKHE008104	Radix chuanxiong;Rhizoma Chuanxiong	川芎			1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE008834	Radix seu Rhizoma rdostachyos	甘松			To regulate the flow of qi and relieve pain, and to invigorate the spleen function./Stomachache, distention fullness in chest and abdomen, headache, hysteria, beriberi.
TCMBANKHE009030	Resi myrrhae;Myrrha	没药			1. To invigorate blood and stop pain; 2. To reduce swelling and promote healing/Stasis pain in chest and abdomen, amenorrhea, dysmenorrhea, concretion and conglomeration, knocks and falls, swollen welling abscess and sores, intestinal welling abscess, red eyes with gall.
TCMBANKHE007874/YEM-381	Glycine max|Glycine max(L.)Merr.	黑大豆叶|大豆	黄豆	云南民族药物志：第二卷	To disinhibit water and free strangury, cool blood and resolve toxin./Blood strangury, snake bite.	彝族
TCMBANKHE008400/YEM-381	Glycine max|Glycine max(L.)Merr.	黑大豆|大豆	黄豆	云南民族药物志：第二卷	To quicken blood and disinhibit water, dispel wind and resolve toxin, fortify spleen and boost kidney./Edema distention fullness, wind toxin and beriberi, jaundice edema, kidney vacuity lumbago, enuresis, wind impediment and hypertonicity of sinews, postpartum wind tetany, clenched jaw, swelling toxin of welling abscess and sore, drug poisoning, food poisoning.	彝族
TCMBANKHE004643/YEM-590/XU-716	Folium Mori|Morus alba L.|Morus alba	桑叶|桑	桑叶	云南民族药物志：第三卷|云南省昭通市盐津县	To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision.	阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE006193/YEM-637	Vicia faba|Vicia faba L.	蚕豆叶|蚕豆	蚕豆	云南民族药物志：第四卷	To stanch bleeding, close sores./Tuberculosis and hemoptysis, bleeding of digestive tract, bleeding due to external injury, shank sore.	傣族/佤族/彝族
TCMBANKHE003731/YEM-686	Litchi chinensis|Litchi chinensis Sonn.	荔枝	荔枝	云南民族药物志：第四卷	To engender liquid and boost blood, rectify qi and relieve pain./Vexation and thirst, hiccough, stomachache, scrofula, swelling of clove, toothache, bleeding due to external injury.	阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族
TCMBANKHE006555/YEM-691	Mangifera indica|Mangifera indica L.	杧果	杧果	云南民族药物志：第四卷	To boost stomach, engender liquid, check vomiting, relieve cough./Thirst, vomiting, reduced food intake, cough.	阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/彝族/藏族/壮族
TCMBANKHE008008/YEM-719/XU-544	Syzygium cumini|Syzygium cumini(L.)Skeels	羊屎果|乌楣|乌墨	乌楣	云南民族药物志：第四卷|云南省德宏州陇川县户撒乡	To constrain lung and settle asthma, engender liquid, astringe intestines./Taxation damage cough, vacuity asthma, fluid damage and thirst, chronic diarrhea and dysentery.	基诺族/佤族/藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI005342	Autistic Disorder	disease	Mental Disorders	27752075
TCMBANKDI009400	Child Development Disorders, Pervasive	group	Mental Disorders	27752075
TCMBANKDI021523	Language Disorders	group	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	27752075
TCMBANKDI026352	Language Development Disorders	group	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	27752075

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述