Compound Summary


  Compound Information

药名:

Deoxyvasicinone

别名:

Pyrrolo(2,1-b)quinazolin-9(1H)-one, 2,3-dihydro-; 1,2,3,10-tetrahydro-pyrrolo[2,1-b]quinazolin-9-one; AC1Q1HJF; BG00602365; BBL028460; InChI=1/C11H10N2O/c14-11-8-4-1-2-5-9(8)12-10-6-3-7-13(10)11/h1-2,4-5H,3,6-7H; AC1Q6FYI; ST50135008; 1H,2H,3H,9H-pyrrolo[2,1-b]quinazolin-9-one; SCHEMBL864139; 4-hydropyrrolidino[2,1-b]quinazolin-5-one; AKOS002210198; VARHXCYGZKSOOO-UHFFFAOYSA-N; DTXSID90201049; deoxyvasicinone; W1018; STOCK1N-00997; cid_68261; Pyrrolo[2,1-b]quinazolin-9(1H)-one, 2,3-dihydro-; MolPort-000-489-741; CHEBI:4435; 3H-Quinazolin-4-one, 2,3-trimethyleno; FCH831074; SR-01000434191; 2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one\n2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one\n2,3-Dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one; BDBM50244216; SMR000024071; HMS2507B03; MLS000088451; MFCD00247051; STL373117; ZINC226366; NSC 159478; AC1L29DJ; BB_NC-02943; SR-01000434191-1; CHEMBL456881; NSC159478; ZINC00226366; 4CN-1561; MCULE-8877508828; NSC-159478; 530-53-0; BB_NC-1382; C10659; 2,3-Dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one; Pyrrolo[2,1-b]quinazolin-9(1H)-one,2,3-dihydro-; Desoxyvasicinon; 2,3-Trimethylene-4-quinazolone; 2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one

分子式:

C11H10N2O

Smiles:

C1CC2=NC3=CC=CC=C3C(=O)N2C1

成分:

HBIN023402

OB_score:

56.293727

CAS_id:

530-53-0

SymMap_id:

SMIT02801;SMIT15008

TCMID_id:

5218

TCMSP_id:

MOL000135

PubChem_id:

68261


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001065 Dioscorea futschauensis To dispel wind-damp, disinhibit damp and turbidity, disperse swelling toxin./Wind-damp impediment pain, strangury with pain, white turbidity, leukorrhea, damp sore.
TCMBANKHE001777 Rhizoma Dioscoreae Nipponicae 穿山龙 1. To promote blood circulation and dredge the channels. 2. To expel wind and dampness. 3. To eliminate phlegm, and relieve cough and dyspnea. 4. To clear toxic materials and relieve swelling./1. Its saponins are antitussives and expectorants.2. Its decoction can relax histamine- or acetylcholine-induced bronchial spasm in guinea-pigs.3. Decreasing cholesterol level, slowing heart rate and increasing coronary flow.4. Anti-allergic.
TCMBANKHE006919 flos farfarae 款冬花 To relieve cough and resolve phlegm to nourish the lung to keep the adverse qi downward./Cough, cough and asthma with abundant phlegm, consumption cough and hemoptysis, chronic bronchitis, infection of upper respiratory tract, tuberculosis.
TCMBANKHE005809 Dioscorea parviflora 小花盾叶薯蓣 To clear heat and resolve toxin, quicken blood and disperse swelling./Swelling toxin of welling abscess and boil, soft tissue sprain, bee sting, insect bites.
TCMBANKHE004685 Dioscorea althaeoides 蜀葵叶薯蓣 To course wind and dispel damp, fortify spleen and disperse food, quicken blood and disperse swelling./common cold with headache, wind-damp impediment pain, food accumulation distention and fullness, indigestion, knocks and falls.
TCMBANKHE007411 Dioscorea panthaica 黄山药 To rectify qi and relieve pain, resolve toxin and disperse swelling./Qi stagnation stomachache, vomiting diarrhea with abdominal pain, taxation detriment due to knocks and falls, toxin swelling of sores, poisonous snake bite.
TCMBANKHE006158 Dioscorea zingiberensis 盾叶薯蓣 To clear lung and relieve cough, disinhibit damp and free strangury, free network vessels and relieve pain, resolve toxin and disperse swelling./Lung heat cough, damp-heat strangury pain, wind-damp lumbago, swollen welling abscess and malign sore, sprain from knocks and falls, bee sting, insect bites.
TCMBANKHE008402 Dioscorea gracillima 纤细薯蓣 See Dioscorea hypoglauca./See Dioscorea hypoglauca.
TCMBANKHE007377 Peganum nigellastrum 骆驼蒿 To dispel damp and resolve toxin, quicken blood and relieve pain, diffuse lung and suppress cough./Arthritis, menstrual disorder, bronchitis, headache.
TCMBANKHE005696/XU-552 Peganum harmala 骆驼蓬 甘肃省定西市岷县 To diffuse lung qi, dispel wind-damp, disperse swelling toxin./Cough and shortness of breath, wind-damp impediment pain, itchy skin, innominate toxin swelling.
TCMBANKHE008332 绵萆薢 Strangury with white turbidity, excessive leukorrhea, damp-heat sore toxin, impediment pain in lumbus and knees.
TCMBANKHE005763/XU-552 Peganum harmala 骆驼蓬子|骆驼蓬 甘肃省定西市岷县 To relieve cough and calm asthma, dispel wind-damp, resolve depression./Cough and asthma, inhibited urination, numbness in limbs, aching pain in joints.
TCMBANKHE007854 Dioscorea nipponica 穿龙薯蓣 To dispel wind and eliminate damp, quicken blood and relieve pain, relieve cough and dispel phlegm./Pain in joints, rheumatic endocarditis, sciatica, chronic bronchitis, chronic trachitis, wind-cold-damp impediment, indigestion, taxation detriment and sprain, malaria, swollen welling abscess.
TCMBANKHE003914/YEM-562 Dioscorea collettii|Dioscorea collettii Hook.f. 叉蕊薯蓣 叉蕊薯蓣 云南民族药物志:第三卷 To dispel wind and disinhibit damp, free network vessels and relieve pain, clear heat and resolve toxin./Wind-damp impediment pain, hypertonicity and numbness, qi stagnation stomachache, damp-heat jaundice, white turbidity, strangury with pain, leukorrhea, knocks and falls, damp sore with swelling toxin, wind papules, eczema, poisonous snake bite. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE007349/YEM-562 Dioscorea hypoglauca [Syn. Dioscorea collettii var. hypoglauca]|Dioscorea collettii Hook.f. 萆薢|叉蕊薯蓣 叉蕊薯蓣 云南民族药物志:第三卷 To disinhibit damp and turbidity, dispel wind-damp./Unctuous strangury, white turbidity, vaginal discharge, sores, wind-damp impediment pain. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE005203/YEM-999/XU-341 Radix Isatidis seu Baphicacanthi|Isatis indigotica Fort.|Isatis indigotica 板蓝根|菘蓝 板蓝根 云南民族药物志:第五卷|山东省菏泽市 To remove toxic heat, to reduce heat in blood, and to soothe sore throat./Epidemic encephalitis, measles papulis, parotitis, influenza, warm toxin macular eruption, ardent fever with headache, massive head scourge, throat pain, maculopapular eruption, epidemic parotitis, erysipelas, hepatitis, swelling toxin of sore and welling abscess. 回族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001194 ADRA2A ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 adrenoceptor alpha 2A
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014790 ADRB1 ADRB1R; B1AR; BETA1AR; FNSS2; RHR adrenoceptor beta 1