Compound Summary


  Compound Information

药名:

Cheilanthifoline

别名:

cheilanthifoline; CHEMBL1209678; cheilanthifolin(e); Chelianthifoline

分子式:

C19H19NO4

Smiles:

COC1=C(C=C2C3CC4=C(CN3CCC2=C1)C5=C(C=C4)OCO5)O

成分:

HBIN020260

OB_score:

46.505038

CAS_id:

483-44-3

SymMap_id:

SMIT10318;SMIT14629

TCMID_id:

3494

TCMSP_id:

MOL009149

PubChem_id:

5117621


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE005790 Menispermum dauricum 蝙蝠葛根 To clear heat and resolve toxin, disperse swelling and relieve pain, disinhibit damp./Swelling pain in throat, lung heat cough, epidemic parotitis, diarrhea, jaundice, wind-damp impediment pain, swelling pain from hemorrhoids, snake or insect bites.
TCMBANKHE006056 Rhizoma Menispermi 北豆根 To remove toxic heat and relieve rheumatic pains./Treatment of sore throat, colitis, dysentery, rheumatic arthralgia.
TCMBANKHE004901 Dicentra spectabilis 荷包牡丹根 To dispel wind, quicken blood, settle pain./Incised wound, sore toxin, stomachache.
TCMBANKHE008052 Corydalis incisa 紫花鱼灯草 To resolve toxin and kill worms, relieve pain./Toxin swelling of sores, scab and lai, intractable lichen, eczema, poisonous snake bite.
TCMBANKHE000631/YEM-135 herba meconpsis integrifoliae|Meconopsis integrifolia(Maxim.) Franch. 绿绒蒿|全缘叶绿绒蒿 全缘叶绿绒蒿 云南民族药物志:第一卷 傈僳族/藏族
TCMBANKHE004261/YNS-302/YEM-404/XU-755 Phyllanthus emblica|Phyllanthus emblica L. 庵摩勒|余甘子 余甘子树皮|滇橄榄 云南药材标准:第三册|云南民族药物志:第二卷|广东省廉江市石岭镇 解毒消肿,收敛止血,杀菌去腐,用于痈肿,疳疔疮毒,阴囊湿疹,外伤出血,跌打损伤,蛇虫叮咬。|To relieve cough and transform phlegm, engender liquid and allay thirst, resolve toxin./Common cold with fever, cough, throat pain, diphtheria, enteritis, diarrhea, eczema, heat vexation and thirst. 阿昌族/白族/布朗族/傣族/哈尼族/基诺族/拉祜族/傈僳族/纳西族/普米族/佤族/瑶族/彝族/藏族/壮族
TCMBANKHE006825/YNS-302/YEM-404/XU-755 Phyllanthus emblica|Phyllanthus emblica L. 油柑木皮|余甘子 余甘子树皮|滇橄榄 云南药材标准:第三册|云南民族药物志:第二卷|广东省廉江市石岭镇 解毒消肿,收敛止血,杀菌去腐,用于痈肿,疳疔疮毒,阴囊湿疹,外伤出血,跌打损伤,蛇虫叮咬。|To clear heat and disinhibit damp, cool blood and resolve toxin./Mouth sore, clove sore, hemorrhoids, scrotal eczema, bleeding due to external injury. 阿昌族/白族/布朗族/傣族/哈尼族/基诺族/拉祜族/傈僳族/纳西族/普米族/佤族/瑶族/彝族/藏族/壮族
TCMBANKHE005888/YNS-302/YEM-404/XU-755 Phyllanthus emblica|Phyllanthus emblica L. 油柑叶|余甘子 余甘子树皮|滇橄榄 云南药材标准:第三册|云南民族药物志:第二卷|广东省廉江市石岭镇 解毒消肿,收敛止血,杀菌去腐,用于痈肿,疳疔疮毒,阴囊湿疹,外伤出血,跌打损伤,蛇虫叮咬。|To clear heat and resolve toxin, disinhibit damp and disperse swelling./Mouth sore, clove sore, eczema, dermatitis, edema, hypertension, poisonous snake bite, knocks and falls. 阿昌族/白族/布朗族/傣族/哈尼族/基诺族/拉祜族/傈僳族/纳西族/普米族/佤族/瑶族/彝族/藏族/壮族
TCMBANKHE006576/YEM-61/XU-569 Fructus Chebulae|Terminalia chebula Retz.|Terminalia chebula var. tomentella 诃子|微毛诃子 诃子 云南民族药物志:第一卷|云南省临沧市永德县 To check diarrhea and chronic cough, and to soothe the sore throat./Chronic diarrhea and dysentery, hematochezia, prolapse of rectum, cough and asthma due to lung vacuity, incessant cough, aphonia due to throat pain. 阿昌族/傣族/德昂族/景颇族/傈僳族/藏族
TCMBANKHE004574/YEM-665 Poria|Poria cocos(Schw.)Wolf 茯苓 茯苓 云南民族药物志:第四卷 To cause diuresis, to invigorate the spleen function, and to calm the mind./Neurasthenia, disquieted heart spirit, fright palpitation and insomnia, insomnia, pelvic inflammation, edema, scant urine with edema, phlegm-rheum dizziness, reduced food intake due to spleen vacuity, sloppy stool and diarrhea, chronic diarrhea. 阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE007344/YEM-665 Poria; Sclerotium Poriae Cocos; Sclerotium Poriae Cocos|Poria cocos(Schw.)Wolf 茯苓; 云苓|茯苓 茯苓 云南民族药物志:第四卷 To cause diuresis, to invigorate the spleen function, and to calm the mind.; Treatment of edema with oliguria, dizziness and palpitation caused by retained fluid, diminished function of the spleen marked by anorexia, loose stools or diarrhea, restlessness and insomnia./Neurasthenia, disquieted heart spirit, fright palpitation and insomnia, insomnia, pelvic inflammation, edema, scant urine with edema, phlegm-rheum dizziness, reduced food intake due to spleen vacuity, sloppy stool and diarrhea, chronic diarrhea.; 1. An active component pachyman promotes macrophage phagocytosis in mice, and enhances lymphocyte-blastogensis rate in vitro.2. Preventing the formation of gastric ulcer under stress in rats3. Diuretic and liver-protective. 阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000121 KCNH2 ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1 potassium voltage-gated channel subfamily H member 2
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000425 DRD1 DADR; DRD1A dopamine receptor D1
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003157 CHRM2 HM2 cholinergic receptor muscarinic 2
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE003643 F7 SPCA coagulation factor VII
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE008124 ADRA2B ADRA2L1; ADRA2RL1; ADRARL1; ALPHA2BAR; FAME2; alpha-2BAR adrenoceptor alpha 2B
TCMBANKGE008702 OPRM1 LMOR; M-OR-1; MOP; MOR; MOR1; OPRM opioid receptor mu 1
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha
TCMBANKGE009294 HTR3A 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3 5-hydroxytryptamine receptor 3A
TCMBANKGE009455 CHRM5 HM5 cholinergic receptor muscarinic 5
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE011923 CHRM4 HM4; M4R cholinergic receptor muscarinic 4
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE012345 DRD3 D3DR; ETM1; FET1 dopamine receptor D3
TCMBANKGE014625 OPRD1 DOP; DOR; DOR1; OPRD opioid receptor delta 1