Compound Summary


  Compound Information

药名:

Hydroxygenkwanin

别名:

2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-chromen-4-one; ACon1_000842; MEGxp0_000798; AIDS-219930; AIDS219930; 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-4-chromenone; hydroxygenkwanin; 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxychromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-chromone

分子式:

C22H22O11

Smiles:

COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)O)O

成分:

HBIN029720

OB_score:

36.466997

CAS_id:

6980-25-2

SymMap_id:

SMIT07276

TCMID_id:

10136

TCMSP_id:

MOL005530

PubChem_id:

5318214


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003782 Fructus Corni 山茱萸 To replenish the liver and kidney, restrain seminal discharge and relieve collapse./Dizziness and tinnitus, aching in lumbus and knees, impotence and emission, enuresis and frequent urination, flooding and spotting with vaginal discharge, vacuity and profuse sweating, vacuity desertion due to great sweating, diabetes mellitus due to internal heat, dysmenorrhea.
TCMBANKHE004098 Herba Swertiae 青叶胆 To increase the flow of bile, and to remove heat and damp./Damp-heat jaundice, heat strangury with inhibited pain, damp-heat diarrhea dysentery, red and white vaginal discharge, influenza, malaria with fever, acute gastritis, acute pharyngolaryngitis, acute tonsillitis, acute conjunctivitis, allergic dermatitis.
TCMBANKHE006523/XU-115 Flos Genkwa|Daphne genkwa Sieb. et Zucc 芫花 湖北神农架 1. To transform water and stop cough; 2. To resolve phlegm and stop cough; 3. To kill worms/Edema, ascites, hydrothorax, cough with profuse phlegm, chronic bronchitis, malaria, scalp infection, infection of skin, tinea capitis, neurodermatitis, induce abortion, toothache.
TCMBANKHE006421/YEM-1037/XU-804 Trichosanthes kirilowii Maxim.|Trichosanthes kirilowii 瓜蒌|栝楼 天花粉 云南民族药物志:第五卷|云南省昭通市盐津县 Angina pectoris, lung heat cough, chest impediment, diabetes mellitus, acute mastitis, constipation, swelling toxin of welling abscess and sore. 苗族/彝族
TCMBANKHE006668/YEM-19 Aquilaria sinensis|Aquilaria sinensis (Lour.) Spreng. 白木香 沉香 云南民族药物志:第一卷 See Aquilaria agallocha./See Aquilaria agallocha . 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族
TCMBANKHE005639/YEM-856 Gelsemium elegans|Gelsemium elegans(Gardn et Champ.)Benth. 钩吻|断肠草 断肠草 云南民族药物志:第五卷 To dispel wind and attack toxin, disperse swelling and relieve pain, anticancer (itself with high toxicity)./Nose carcinoma, eczema, neuralgia, wind-damp impediment pain, scab and lai , scrofula, clove sore, knocks and falls. 阿昌族/布朗族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/佤族/瑶族/壮族
TCMBANKHE007056/YEM-9 Herba Lobeliae Chinensis|Lobelia chinensis Lour. 半边莲 半边莲 云南民族药物志:第一卷 To cause diuresis, and to remove toxic heat./Edema, edema and enlarged abdomen, edema in face and foot, swollen welling abscess and clove sores, snake or insect bites. 阿昌族/傣族/德昂族/景颇族/傈僳族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000784 CALM3 CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 calmodulin 3
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1