Compound Summary


  Compound Information

药名:

Eriodyctiol (flavanone)

别名:

(2R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-chroman-4-one; ZINC00058116; (2R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-chromanone; (2R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-4-one; 4049-38-1; NCI60_017216; NSC649412

分子式:

C15H12O6

Smiles:

C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(C=C3)O)O

成分:

HBIN025600

OB_score:

41.350427

CAS_id:

4049-38-1

SymMap_id:

SMIT05073

TCMSP_id:

MOL002914

PubChem_id:

373261


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE004862 Lignum Dalbergiae odoriferae Rosewood 降香 To relieve pain by promoting the circulation of qi and blood, and to arrest bleeding./Shortening the plasma recalcification time in rabbits.
TCMBANKHE003163 Testa Arachidis Hypogaeae 花生衣 To stop bleeding by astringing bleeding and enrich blood. /Inhibiting fibrinolysis, promoting thrombocytopoiesis and shortening the bleeding time.
TCMBANKHE003723 Flos Lonicerae 金银花 To remove toxic heat and dispel wind-heat./Infection of upper respiratory tract, tonsillitis, acute laryngitis, skin suppurations, welling abscess, viral conjunctivitis, influenza, pneumonia, mastitis, acute appendicitis, warm disease fever, heat toxin blood dysentery, swollen welling abscess and clove sores, throat impediment.
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE003952 Folium Rhododendri Daurici 满山红 Acute bronchitis, chronic bronchitis.
TCMBANKHE005226 Rhizoma Dryriae 骨碎补 To replenish the kidney, to strengthen the bones, to promote the healing of fracture, and to relieve pain./Kidney vacuity lumbago, tinnitus and deafness, tooth mobilizing, wrenching and contusion from knocks and falls, sinew and bone wound, alopecia areata, white patch wind.
TCMBANKHE007122 Fructus Aurantii Immaturus 枳实 To eliminate stagnation of qi, resolve phlegm and relieve stuffiness sensation in the chest and abdomen./Shock, indigestion, ptosis of anus or uterus, cardiac failure, distention fullness in chest and abdomen, phlegm aggregation.
TCMBANKHE007551 Catechu 儿茶 To reduce toxic and to remove dampness./To arrest exudation, promote the growth of new tissue, and cure wounds.
TCMBANKHE005899/XU-345 Spina gleditsiae;Spi gleditsiae|Gleditsia sinensis 皂刺;皂角刺|皂荚 云南省曲靖市会泽县 Treatment of carbuncle and boil at the early stage or formation of abscess difficult to burst, external use for scabies and leprosy. /1. To relieve carbuncle and drain pus. For the early stage of carbuncle or carbuncle with unruptured abscess. 2. To expel wind and kill parasites. For tinea infection and leprosy.
TCMBANKHE007939/YEM-89 Rhizoma Fagopyri Cymosi|Fagopyrum dibotrys (D.Don)Hara 金荞麦 金荞麦 云南民族药物志:第一卷 1. Its extractum and component flavanol promotes macrophage phagocytosis in the peritoneum of mouse.2. Flavanol is also an anti-inflammatory component. It promotes blood circulation and inhibits the agglutination of blood platelet./1. To clear heat and toxic material. For lung abscess, cough due to lung-heat, also for sorethroat and skin infection. 2. To promote blood circulation to eliminate blood stasis. For menorrhalgia due to blood stasis, postpartum abdominal pain due to blood 傣族/哈尼族/基诺族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000784 CALM3 CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 calmodulin 3
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE004437 PYGM GSD5 glycogen phosphorylase, muscle associated
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1