Compound Summary

  Compound Information

TCMBANKIN016027

药名:	Swertianin
别名:	LS-162497; AX8245763; 9H-Xanthen-9-one, 1,2,8-trihydroxy-6-methoxy-; BDBM50155435; 6-Methoxy-1,2,8-trihydroxyxanthen-9-one; C10092; UNII-890WXQ4KC0; ST24036670; CHEMBL187044; 1,2,8-Trihydroxy-6-methoxy-9H-xanthen-9-one; KB-216271; FT-0697995; AKOS016010617; 890WXQ4KC0; AK120347; 20882-75-1; 1,2,8-trihydroxy-6-methoxy-xanthen-9-one; AC1NQYU7; NSC 289490; Xanthen-9-one, 6-methoxy-1,2,8-trihydroxy-; 4CH-024750; BG01566899; swertianin; NSC-289490; SWERTIANINE; BG01566898; BRN 1351024; 1,2,8-Trihydroxy-6-methoxy-xanthen-9-one; 1,7,8-trihydroxy-3-methoxyxanthone; AJ-55459; CHEBI:9371; ZINC5998778; Gentiakochianin; 0679AB; ST077131; 1,2,8-trihydroxy-6-methoxyxanthen-9-one; Q-100263; NSC289490; DTXSID60174998; 1,2,8-trihydroxy-6-methoxy-9-xanthenone; 1,2,8-trihydroxy-6-methoxy-xanthone; 1,2,8-Trihydroxy-6-methoxyxanthone; 5-18-05-00186 (Beilstein Handbook Reference); 9H-Xanthen-9-one, 1,2,8-trihydroxy-6-methoxy- (9CI)
分子式:	C14H10O6
Smiles:	COC1=CC(=C2C(=C1)OC3=C(C2=O)C(=C(C=C3)O)O)O
成分:	HBIN045188
OB_score:	28.668832
CAS_id:	20882-75-1
SymMap_id:	SMIT05269;SMIT17836
TCMID_id:	20494
TCMSP_id:	MOL003138
PubChem_id:	5281661

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000262	Swertia chirata
TCMBANKHE002046		金果揽			See Tinospora sagittata .
TCMBANKHE002286	Gentiana kochiana
TCMBANKHE003730	Gentiana scabra var. buesgeri	龙胆			Acute icterohepatitis, urinary tract infection, acute conjunctivitis, dribbling pain of urination, damp-heat jaundice, genital swelling and itch, damp-heat vaginal discharge, distended head and headache due to liver-gallbladder repletion fire, red eyes with gall, deafness, swelling in ear, pain in rib-side, bitter taste, fright wind and convulsion.
TCMBANKHE003801	Swertia calycina	苞萼獐牙菜
TCMBANKHE003804	Swertia pseudochinensis	獐牙菜			To drain fire and resolve toxin, disinhibit damp, fortify spleen./Acute icterohepatitis, chronic liver diseases, damp-heat jaundice, dysentery, gastritis, indigestion, acute conjunctivitis, toothache, mouth sore, swelling pain of sores.
TCMBANKHE004949	Gentiana bavarica	巴伐利亚龙胆
TCMBANKHE006091	Swertia japonica	日本獐牙菜
TCMBANKHE005640	Swertia erythrosticta	红直獐牙菜			To clear heat and resolve toxin, disinhibit damp and abate jaundice, kill worms./Wind-heat cough, sore swollen throat, jaundice (icterus, ICT), syphilis, swelling and toxin of sore and welling abscess, scab and lichen.
TCMBANKHE009045	Swertia fasciculata	簇花獐牙菜
TCMBANKHE008683/XU-650	Swertia macrosperma	大籽獐牙菜		云南省昆明市呈贡区梁王山
TCMBANKHE006360	Gentiana nivalis	雪龙胆
TCMBANKHE006601	Gentiana japonica	日本龙胆
TCMBANKHE007856	Swertia nervosa	显脉獐牙菜			To clear heat and resolve toxin, quicken blood and regulate menstruation./Jaundice (icterus, ICT), bitter taste, tidal fever.
TCMBANKHE008633	Gentiana brachyphylla	短叶龙胆
TCMBANKHE009149	Swertia angustifolia	狭叶獐牙菜
TCMBANKHE009040/YNS-331	Swertia punicea var. lutescens|Swertia punicea Hemsl	淡黄獐牙菜|紫红獐牙菜	紫红青叶胆	云南药材标准：第一册	清肝利胆，清热利湿。用于黄疸尿赤，热淋涩痛。
TCMBANKHE007125/YNS-261	Swertia patens|Swertia patens Burk.	斜茎獐牙菜|金沙獐牙菜	小儿腹痛草	云南药材标准：第一册	疏肝清热，和胃止痛。用于胃痛，腹痛，胁痛，风火牙痛，咽喉肿痛|To warm center and relieve pain, fortify spleen and disperse accumulation./Infant common cold, spasmodic abdominal pain, child gan accumulation, indigestion.
TCMBANKHE007892/YNS-331	Swertia punicea|Swertia punicea Hemsl	紫红獐牙菜	紫红青叶胆	云南药材标准：第一册	清肝利胆，清热利湿。用于黄疸尿赤，热淋涩痛。|To clear liver and disinhibit gallbladder, clear heat and resolve toxin, disinhibit damp./Acute icterohepatitis, cholecystitis, wind-heat common cold, wind-fire toothache, swelling pain in throat, indigestion, acute bacillary dysentery, infection of urinary system, tinnitus and deafness, burns and scalds.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE008172	MAOA	BRNRS; MAO-A	monoamine oxidase A
TCMBANKGE014941	DPEP1	MBD1; MDP; RDP	dipeptidase 1