Compound Summary


  Compound Information

药名:

gentianine

别名:

AKOS005266580; Gentianine; ZINC1530467; MCULE-3837896278; 439-89-4; NSC606848; 4-(2-hydroxyethyl)-5-vinylnicotinic acid gamma-lactone; BB_NC-0759; 5-vinyl-3-hydro-4H-pyrano[3,4-c]pyridin-1-one; 1H-Pyrano(3,4-c)pyridin-1-one, 5-ethenyl-3,4-dihydro- (9CI); 4-27-00-02817 (Beilstein Handbook Reference); Gencianina; Bio-0278; Q-100479; C2PD310UXB; 1H-Pyrano[3,4-c]pyridin-1-one, 5-ethenyl-3,4-dihydro-; 5-ethenyl-3,4-dihydropyrano[3,4-c]pyridin-1-one; Erythricine; FCH842303; ZINC01530467; From Schultesia guianensis malme (Mata-Zombando); C06525; 5-ethenyl-3,4-dihydro-1H-pyrano[3,4-c]pyridin-1-one; UNII-C2PD310UXB; 5-Ethenyl-3,4-dihydro-1H-pyrano(3,4-c)pyridin-1-one; 5-vinyl-3,4-dihydropyrano[3,4-c]pyridin-1-one; ST023290; CHEBI:28981; NSC-606848; W1062; 1H-Pyrano[3,4-c]pyridin-1-one,5-ethenyl-3,4-dihydro-; 4-(2-Hydroxyethyl)-5-vinylnicotinic lactone; MolPort-002-507-225; SCHEMBL2216852; AC1L74P3

分子式:

C10H9NO2

Smiles:

C=CC1=CN=CC2=C1CCOC2=O

成分:

HBIN027501

SymMap_id:

SMIT01430;SMIT03198

TCMID_id:

8296

TCMSP_id:

MOL000648;MOL008515

PubChem_id:

354616


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000372 Siegesbeckia orientalis 希莶 To dispel wind-damp, free channels and network vessels, clear heat and resolve toxin./Wind-damp impediment pain, lassitude in lumbus and knees, hemiplegia, hypertension, malaria, jaundice, swelling toxin of welling abscess and sore, wind papules, damp sore, animal and insect bites.
TCMBANKHE000706 Flos Gentianae straminae 秦艽花
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE002046 金果揽 See Tinospora sagittata .
TCMBANKHE002363 Salmiacum 硒砂
TCMBANKHE003730 Gentiana scabra var. buesgeri 龙胆 Acute icterohepatitis, urinary tract infection, acute conjunctivitis, dribbling pain of urination, damp-heat jaundice, genital swelling and itch, damp-heat vaginal discharge, distended head and headache due to liver-gallbladder repletion fire, red eyes with gall, deafness, swelling in ear, pain in rib-side, bitter taste, fright wind and convulsion.
TCMBANKHE003739 龙葵 Clove sore, swollen welling abscess, erysipelas, sprain from knocks and falls, mastitis, cervicitis, chronic bronchitis, chronic trachitis, acute nephritis, dysentery, infection of skin, leukorrhea, scant urine in children.
TCMBANKHE003771 Gentiana dahurica 达乌里秦艽 See Gentiana macrophylla./See Gentiana macrophylla.
TCMBANKHE003848 Gryllulus chinensis 蟋蟀 To disinhibit urine./Urinary stoppage, edema, ascites.
TCMBANKHE006128 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE005029 Gentiana straminea 麻花艽 See Gentiana macrophylla./See Gentiana macrophylla.
TCMBANKHE005124 Gentiana algida 白花龙胆 To drain fire and resolve toxin, suppress cough, disinhibit damp./Common cold with fever, lung heat cough, sore pharynx, red eyes, dribbling pain of urination, scrotal eczema.
TCMBANKHE005309 Gentiana tianschanica 天山秦艽 See Gentiana macrophylla./See Gentiana macrophylla.
TCMBANKHE007466 Gentiana tibetica 西藏秦艽 See Gentiana macrophylla./See Gentiana macrophylla.
TCMBANKHE007541 Menyanthes trifoliata 睡菜 To fortify spleen and disperse food, nourish heart and quiet spirit, clear heat and disinhibit urine./Gastritis, indigestion, palpitation and insomnia, damp-heat jaundice, cholecystitis, edema, inhibited urination, inhibited voidings of reddish urine.
TCMBANKHE005606 Gentiana crassicaulis 粗茎秦艽 See Gentiana macrophylla./See Gentiana macrophylla.
TCMBANKHE006287 Herba Portulacae 马齿苋 To remove toxic heat, and to arrest bleeding./Heat toxin blood dysentery, acute bacillary dysentery, pertussis, enteritis, appendicitis, swollen welling abscess and clove sores, eczema, erysipelas, bleeding, postpartum bleeding, hematochezia, bleeding from hemorrhoids, flooding and spotting, ascariasis, ancylostomiasis, snake or insect bites.
TCMBANKHE006342 Gentiana siphonantha 管花秦艽 See Gentiana macrophylla./See Gentiana macrophylla.
TCMBANKHE006430 Radix Gentianae 龙胆草 Treatment of jaundice caused by damp-heat, swelling and itching of the vulva with excessive leukorrhea, prolonged erection of the penis with spontaneous emission, eczema accompanied by itching, blood-shot eyes, impairment of hearing, pain in the costal regions and bitter taste in the mouth, convulsion./Treatment of jaundice caused by damp-heat, swelling and itching of the vulva with excessive leukorrhea, prolonged erection of the penis with spontaneous emission, eczema accompanied by itching, blood-shot eyes, impairment of hearing, pain in the costal re
TCMBANKHE009153 Radix Gentianae macrophyllae 西秦艽 Treatment of rheumatic or rheumatoid arthrits with muscular contracture and severe joint pain, fever recurring daily in the afternoon, fever in infants with malnutrition./1. Inhibiting experimental arthritis in mice and decreasing capillary permeability.2. Anti-allergric.3. Inducing transient hypotensive effect.
TCMBANKHE007947/XU-813 Gentiana rigescens 滇龙胆草 云南省红河州蒙自市 See Gentiana scabra ./See Gentiana scabra .
TCMBANKHE009154 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE000827/YEM-729/XU-517 Herba Adenostemmatis|Adenostemma lavenia(L.)O.Kuntze|Adenostemma lavenia 下田菊 下田菊 云南民族药物志:第四卷|云南红河屏边县 阿昌族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/佤族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE000965 CHRNA7 CHRNA7-2; NACHRA7 cholinergic receptor nicotinic alpha 7 subunit
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001194 ADRA2A ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 adrenoceptor alpha 2A
TCMBANKGE001467 LTA4H - leukotriene A4 hydrolase
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014790 ADRB1 ADRB1R; B1AR; BETA1AR; FNSS2; RHR adrenoceptor beta 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1