Compound Summary
Compound Information
药名: | Cucurbitacin C |
别名: | CUCURBITACIN C; 19-Nor-9beta,10alpha-lanosta-5,23-diene-11,22-dione, 3beta,16alpha,20,25-tetrahydroxy-9-(hydroxymethyl)-, 25-acetate; cucurbitacin c; 19-nor-9.beta.,10.alpha.-Lanosta-5,23-diene-11,22-dione, 3.beta.,16.alpha.,20,25-tetrahydroxy-9-(hydroxymethyl)-, 25-acetate; 19-Norlanosta-5,23-diene-11,22-dione, 25-(acetyloxy)-3,16,20-trihydroxy-9-(hydroxymethyl)-, (3.beta.,9.beta.,10.alpha.,16.alpha.,23E)-; acetic acid [(E,5R)-5-[(3S,8S,9R,10R,13R,14S,16R,17R)-3,16-dihydroxy-9-(hydroxymethyl)-4,4,13,14-tetramethyl-11-oxo-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-5-hydroxy-1,1-dimethyl-4-oxohex-2-enyl] ester; Cucurbitacine (C); LS-97295; [(E,5R)-5-[(3S,8S,9R,10R,13R,14S,16R,17R)-3,16-dihydroxy-9-(hydroxymethyl)-4,4,13,14-tetramethyl-11-oxo-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-5-hydroxy-1,1-dimethyl-4-oxo-hex-2-enyl] acetate; NSC94744; AC1O5G8S; [(E,6R)-6-[(3S,8S,9R,10R,13R,14S,16R,17R)-3,16-dihydroxy-9-(hydroxymethyl)-4,4,13,14-tetramethyl-11-oxo-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxo-hept-3-en-2-yl] ethanoate; 5988-76-1; HSDB 3477; [(E,6R)-6-[(3S,8S,9R,10R,13R,14S,16R,17R)-3,16-dihydroxy-9-(hydroxymethyl)-4,4,13,14-tetramethyl-11-oxo-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate; 19-Norlanosta-5,23-diene-11,22-dione, 25-(acetyloxy)-3,16,20-trihydroxy-9-(hydroxymethyl)-, (3beta,9beta,10alpha,16alpha,23E)-; [(E)-6-[(3S,10R,16R)-3,16-dihydroxy-9-(hydroxymethyl)-4,4,13,14-tetramethyl-11-oxo-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate; NSC 94744; LMST01010105; acetic acid [(E,5R)-5-[(3S,8S,9R,10R,13R,14S,16R,17R)-3,16-dihydroxy-11-keto-4,4,13,14-tetramethyl-9-methylol-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-5-hydroxy-4-keto-1,1-dimethyl-hex-2-enyl] ester; C08795; 25-(Acetyloxy)-3,16,20-trihydroxy-9-(hydroxymethyl)-19-norlanosta-5,23-diene-11,22-dione; 19-Nor-9-beta,10-alpha-lanosta-5,23-diene-11,22-dione, 3-beta,16-alpha,20,25-tetrahydroxy-9-(hydroxymethyl)-, 25-acetate |
分子式: | C32H48O8 |
Smiles: | CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CCC(C4(C)C)O)CO)C)C)O)O |
成分: | HBIN021847 |
OB_score: | 20.524378 |
CAS_id: | 5988-76-1 |
SymMap_id: | SMIT04677;SMIT14809 |
TCMID_id: | 4317 |
TCMSP_id: | MOL002443 |
PubChem_id: | 44559416 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE003344 | Cucumis africanus | |||||
| TCMBANKHE004718 | Bryonia alba | 白泻根 | ||||
| TCMBANKHE007551 | Catechu | 儿茶 | To reduce toxic and to remove dampness./To arrest exudation, promote the growth of new tissue, and cure wounds. | |||
| TCMBANKHE008763 | Ecballium elaterium | 喷瓜 | ||||
| TCMBANKHE007086 | Strophanthus divaricatus | 羊角坳子 | To quicken blood and disperse swelling, strengthen heart, kill worms and relieve itch./Wind-damp, scab and lichen, knocks and falls, swelling of sores, cardiac failure, rheumatic arthritis. | |||
| TCMBANKHE007029 | Citrullus colocynthis | 药西瓜 | ||||
| TCMBANKHE006580 | Calycis Melo | 瓜蒂 | Vomiting promotion/Wind stroke, epilepsy, throat impediment, indigestion of overnight food, distending pain in stomach duct, damp-heat jaundice, chronic hepatitis, cirrhosis. | |||
| TCMBANKHE008507 | Iberis umbellata | 伞形屈曲花 | ||||
| TCMBANKHE006421/YEM-1037/XU-804 | Trichosanthes kirilowii Maxim.|Trichosanthes kirilowii | 瓜蒌|栝楼 | 天花粉 | 云南民族药物志：第五卷|云南省昭通市盐津县 | Angina pectoris, lung heat cough, chest impediment, diabetes mellitus, acute mastitis, constipation, swelling toxin of welling abscess and sore. | 苗族/彝族 |
| TCMBANKHE006143/YEM-213 | Luffa cylindrica|Luffa cylindrica(L.)Roem. | 丝瓜 | 丝瓜 | 云南民族药物志：第二卷 | To clear heat and resolve phlegm, cool blood and resolve toxin./Febrile diseases with vexation and thirst, cough of phlegm asthma, intestinal wind bleeding, bleeding from hemorrhoids, blood strangury, flooding and spotting, sores with welling abscess and flat abscess, galactostasis, innominate toxin swelling, edema. | 阿昌族/傣族/德昂族/景颇族/傈僳族/水族/彝族/藏族 |
| TCMBANKHE008177/YEM-315 | Lagenaria siceraria var. depressa|Lagenaria siceraria( Molina )Standl. | 瓠瓜|葫芦 | 葫芦 | 云南民族药物志：第二卷 | To disinhibit water, disperse swelling, free strangury, dissipate binds./Edema, ascites, jaundice, diabetes mellitus, strangury, swollen welling abscess. | 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族 |
| TCMBANKHE007848/YEM-669 | Cucumis sativus var. hanzil|Cucumis sativus L. | 苦黄瓜|黄瓜 | 黄瓜 | 云南民族药物志：第四卷 | 傣族/哈尼族/佤族/彝族 | |
| TCMBANKHE004426/YEM-669 | Cucumis sativus|Cucumis sativus L. | 黄瓜 | 黄瓜 | 云南民族药物志：第四卷 | To clear heat, disinhibit water, resolve toxin./Febrile diseases thirst, short voidings of reddish urine, burns and scalds, scant urine with edema, sweat macule, prickly heat. | 傣族/哈尼族/佤族/彝族 |
| TCMBANKHE008148/YEM-669 | Cucumis sativus|Cucumis sativus L. | 黄瓜 | 黄瓜 | 云南民族药物志：第四卷 | To clear heat, disinhibit water, resolve toxin./Febrile diseases thirst, short voidings of reddish urine, burns and scalds, scant urine with edema, sweat macule, prickly heat. | 傣族/哈尼族/佤族/彝族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000168 | NR3C1 | GCCR; GCR; GCRST; GR; GRL | nuclear receptor subfamily 3 group C member 1 |
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