Compound Summary


  Compound Information

药名:

haplopine

别名:

AC1Q6BZM; TimTec1_005697; ST083386; Oprea1_418227; ZINC5998737; AC1L4WKL; HMS1550C21; 1363-10-6; 4,8-dimethoxy-furo[2,3-b]quinolin-7-ol, AldrichCPR; MLS001049015; AKOS032948939; HMS3561H11; AIDS-342575; Oprea1_182538; A835051; STK762192; 7-Hydroxy-8-methoxydictamnine; 9509AF; MCULE-1281961921; CTK5A8833; AIDS342575; C10694; 4,8-dimethoxyfuro[2,3-b]quinolin-7-ol; Heliparvifoline; CHEMBL400257; Bio-0229; BAS 00513816; MolPort-001-898-934; 4,8-dimethoxyfuro[2,3-b]quinolin-7(9h)-one; 4,8-dimethoxy-9H-furo[2,3-b]quinolin-7-one; ZINC00083885; SCHEMBL15263337; 5876-17-5; 4,8-Dimethoxy-furo[2,3-b]quinolin-7-ol; Furo[2,3-b]quinoline, 4,8-dimethoxy-7-hydroxy-; AKOS000635187; CHEMBL455007; 4,8-dimethoxyfurano[2,3-b]quinolin-7-ol; CHEBI:5620; HMS2270N15; SMR000387023; Furo(2,3-b)quinolin-7-ol, 4,8-dimethoxy-; A2194/0092285; Haplopine

分子式:

C13H11NO4

Smiles:

COC1=C2C=COC2=NC3=C1C=CC(=C3OC)O

成分:

HBIN028793

OB_score:

32.27082

CAS_id:

5876-17-5

SymMap_id:

SMIT00591

TCMID_id:

9225

TCMSP_id:

MOL005096;MOL013270

PubChem_id:

5281846


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000810 Radix Zanthoxyli 两面针 To promote the flow of qi, relieve pain, to eliminate blood stasis, to promote blood circulation and dispel wind./Treatment of traumatic injury, rheumatic arthralgia, stomach-ache, teethache, bitten by venomous snake, applied for burn caused by hot liquid or fire.
TCMBANKHE004459 Fructus Lycii 枸杞子 To benefit the liver and the kidney, to replenish vital essence and to improve eyesight./Lassitude in lumbus and knees, emission, dizziness and dim vision, lung disease with cough, diabetes mellitus.
TCMBANKHE004543 Zanthoxylum cuspidatum 花椒簕 To quicken blood, dissipate stasis, relieve pain./Stasis stagnation pain in stomach duct and abdomen, knocks and falls.
TCMBANKHE005000 Pericarpium Zanthoxyli 花椒 To warm the spleen and the stomach and relieve pain, to kill worms, and to relieve itching./Spleen-stomach vacuity cold, cold pain in stomach duct and abdomen, vomiting, diarrhea, abdominal pain and vomiting due to roundworm.
TCMBANKHE007121 Haplophyllum perforatum 大叶芸香草
TCMBANKHE005444 白鲜皮 To clear heat and dry damp, dispel wind and relieve itch, resolve toxin./1. Inhibiting the growth of pathogenic fungi. 2. Its infusion lowers vaccine-induced fever in rabbits. 3. Dictamnine, one of its active components, increase the myocardial tone of frogs. Dermatitis, psoriasis, icterohepatitis, damp-heat sore and papules, profuse pus, yellow-water sore, damp ulceration on skin, itchy skin, damp-heat jaundice, damp-heat impediment.
TCMBANKHE007829 Pericarpium Zanthoxyli 花椒 To warm the spleen and the stomach and relieve pain, to kill worms, and to relieve itching./Spleen-stomach vacuity cold, cold pain in stomach duct and abdomen, vomiting, diarrhea, abdominal pain and vomiting due to roundworm.

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2