Compound Summary

  Compound Information

TCMBANKIN018434

药名:	Isoarcapillin
别名:	5,6-dihydroxy-2-(4-hydroxy-2,5-dimethoxy-phenyl)-7-methoxy-chromen-4-one; isoarcapillin; 5,6-dihydroxy-2-(4-hydroxy-2,5-dimethoxyphenyl)-7-methoxychromen-4-one; 5,6-dihydroxy-2-(4-hydroxy-2,5-dimethoxy-phenyl)-7-methoxy-chromone; 5,6-dihydroxy-2-(4-hydroxy-2,5-dimethoxyphenyl)-7-methoxy-4-chromenone
分子式:	C18H16O8
Smiles:	COC1=CC(=C(C=C1C2=CC(=O)C3=C(C(=C(C=C3O2)OC)O)O)OC)O
成分:	HBIN030438
OB_score:	57.403715
CAS_id:	85819-50-7
SymMap_id:	SMIT09374
TCMID_id:	11232
TCMSP_id:	MOL008039

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004741	Orixa japonica	臭山羊			To clear heat and resolve exterior, move qi and relieve pain, dispel wind and disinhibit damp./Wind-heat common cold, cough, throat pain, toothache, stomachache, pain in joints due to rheumatalgia, dysentery, innominate toxin swelling.
TCMBANKHE007973	Herba Artemisiae Scopariae	茵陈			To remove damp-heat and relieve jaundice./1. Its decoction or its volatile oil, and active components such as chlorogenic acid, caffeic acid and hydroxyacetophenone are chologogues.2. Protecting the liver of experimental animals from the damage of CCl4.3. Decreasing the level of blood lipids and alleviating artherosclerosis and lipidosis in rabbits.4. Increasing the coronary flow of rabbits in vitro.5. Its volatile oil inhibits the growth of Shigella dysenteriae, Hemolytic streptococcus and various dermatomyces in vitro.6. Anticoagulative.
TCMBANKHE004550/YEM-551	Artemisia capillaris|Artemisia capillaris Thunb.	茵陈蒿	茵陈	云南民族药物志：第三卷	To clear heat and disinhibit damp, abate jaundice./Hepatitis, jaundice, infective cholecystitis, hyperlipemia, inhibited urination, damp sore, itchy skin.	阿昌族/傣族/德昂族/景颇族/傈僳族/瑶族/彝族/藏族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000784	CALM3	CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3	calmodulin 3
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE003643	F7	SPCA	coagulation factor VII
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1