Compound Summary

  Compound Information

TCMBANKIN018561

药名:	Wighteone
别名:	AIDS071696; AIDS-071696; 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)chromen-4-one; wighteone; 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)-4-chromenone; C10542; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-; 51225-30-0; 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)chromone
分子式:	C20H18O5
Smiles:	CC(=CCC1=C(C2=C(C=C1O)OC=C(C2=O)C3=CC=C(C=C3)O)O)C
成分:	HBIN048245
OB_score:	42.796672
CAS_id:	51225-30-0
SymMap_id:	SMIT05709
TCMID_id:	22651
TCMSP_id:	MOL003673
PubChem_id:	5281814

---

   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000437	Erycibe expansa
TCMBANKHE008503	Radix Sophorae flavescentis	苦参			To remove heat and damp, to kill parasites, and to cause diuresis./Arrhythmia, otitis media, acute conjunctivitis, chronic conjunctivitis, trichomoniasis, septicemia, edema, damp-heat diarrhea, intestinal wind bleeding, acute jaundice, inhibited urination, vaginal discharge, pudendal itch, scab and lichen, leprosy, itchy skin, eczema, damp toxin sore, suppurative nest sore.
TCMBANKHE006338	Glycyrrhiza glabra	光果甘草			See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis .
TCMBANKHE004573	Lupinus albus	白羽扇豆
TCMBANKHE004838	Radix Sophorae Tonkinensis	山豆根			To remove toxic heat, promote the subsidence of swelling, and soothe the sore throat./Septicemia, ulcer of uterine cervix, chronic cervicitis, bacillary dysentery, enteritis, hydatid moles, chorioblastoma, asthma, chronic bronchitis, acute tonsillitis, laryngitis, accumulated fire toxin, swelling pain in throat, gingiva painful swelling.
TCMBANKHE008358	Cudrania cochinchinensis	狗脊			To dispel wind and free network vessels, clear heat and remove damp, resolve toxin and disperse swelling./Wind-damp impediment pain, knocks and falls, jaundice, parotitis, phthisis, gastric ulcer, duodenal ulcer, strangury-turbidity, tympanites, menstrual block, taxation damage and coughing of blood, clove sore and swollen welling abscess.
TCMBANKHE008692	Erythrina variegata [Syn. Erythrina indica ]	刺桐			See Erythrina arborescens./See Erythrina arborescens.
TCMBANKHE007498	Thuja orientalis	侧柏枝节			To dispel wind and eliminate damp, resolve toxin and cure sores./Wind impediment, joint running wind, cholera cramp, gum swelling and pain.
TCMBANKHE006161/YEM-342	Erythrina arborescens|Erythrina arborescens Roxb.	乔木刺桐|鹦哥花	鹦哥花	云南民族药物志：第二卷	To dispel wind and eliminate damp, soothe sinews and quicken network vessels, kill worms and relieve itch./Wind-damp impediment pain, hypertonicity in limb joints, knocks and falls, scab and lichen, eczema.	白族/傣族/哈尼族/苗族/彝族

---

   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

---

   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000784	CALM3	CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3	calmodulin 3
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1