Compound Summary

  Compound Information

TCMBANKIN018789

药名:	eckol
别名:	88798-74-7; CHEMBL471187; 1-(3,5-Dihydroxyphenoxy)-2,4,7,9-tetrahydroxydibenzo-1,4-dioxin; 4-(3,5-dihydroxyphenoxy)-dibenzo(b,e)(1,4)dioxin-1,3,6,8-tetrol; D08MZY; Dibenzo[b,e][1,4]dioxin-1,3,6,8-tetrol, 4-(3,5-dihydroxyphenoxy)-; DTXSID40237333; ZINC6091359; 4-(3,5-dihydroxyphenoxy)oxanthrene-1,3,6,8-tetrol; AC1L3S7Z; BDBM50259982; CHEBI:65819; AIDS209851; Eckol; SCHEMBL2562621; Dibenzo(b,e)(1,4)-dioxin-1,3,6,8-tetrol, 4-(3,5-dihydroxyphenoxy)-; AIDS-209851; 4-(3,5-dihydroxyphenoxy)dibenzo-p-dioxin-1,3,6,8-tetrol
分子式:	C18H12O9
Smiles:	C1=C(C=C(C=C1O)OC2=C(C=C(C3=C2OC4=C(C=C(C=C4O3)O)O)O)O)O
成分:	HBIN024823
OB_score:	87.060268
CAS_id:	88798-74-7
SymMap_id:	SMIT00788
TCMID_id:	6699
TCMSP_id:	MOL010616
PubChem_id:	145937

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000011	Alstonia spatulata
TCMBANKHE004208	Thallus Lamiriae	昆布			To eliminate phlegm, soften hard masses and dissolve lumps, and to cause diuresis./Goiter and tuberculosis, scrofula, bleeding, painful swollen testes, phlegm-rheum and edema, prevention of cataracts.
TCMBANKHE003748	Rhizoma Coptidis	黄连			To remove damp-heat, quench fire and counteract toxicity./Febrile infectious diseases, dysentery, blood ejection, spontaneous external bleeding, diphtheria, infection of upper respiratory tract, scarlatina, typhoid fever, acute conjunctivitis, otitis media, acute surgical infection, septicemia, hepatitis, trichomoniasis, eruptive dermatitis, hypertension, vexation and agitation, clouded spirit with delirious speech, damp-heat glomus in chest, damp-heat diarrhea dysentery, insomnia and vexation due to effulgent fire, stomach heat vomiting, swift digestion with rapid hungering, red eyes with pain due to liver fire, heat toxin sores, clove sore running yellow, gum swelling and pain, mouth sore, tongue sores, genital swelling, bleeding from hemorrhoids, eczema, scalds.
TCMBANKHE007925	Ecklonia stolonifera	棕藻;总皂
TCMBANKHE006266	Alstonia spectabilis	壮观鸡骨常山
TCMBANKHE007699	Alstonia boonei	干老鸡骨常山,干酪鸡骨常山
TCMBANKHE008825	Ecklonia kurome	黑昆布			See Laminaria japonica./See Laminaria japonica.
TCMBANKHE006235/YNS-53/YEM-31	Alstonia scholaris|Alstonia scholaris(Linn.)R.Br.|Alstonia scholaris(L.)R.Br.	象皮木|糖胶树	灯台树/灯台叶|灯台树	云南药材标准：第三册/云南药材标准：第七册|云南民族药物志：第一卷	除风通血，消肿止痛，解毒安胎，止咳化痰。用于风盛所致的头目昏痛；风湿病肢体关节肿胀疼痛；孕期体弱多病，妊娠呕吐，月子病(产后病)出现面色苍白、心悸、胸闷、气短、头昏、头晕，形瘦体弱，咳嗽喘息，失眠多梦等；感冒咳嗽痰多，咽喉肿痛；孕期保健。/止咳祛痰。用于咳嗽，百日咳。|To clear heat and resolve toxin, relieve cough and dispel phlegm, stanch bleeding and disperse swelling./Common cold with fever, lung heat cough asthma, pertussis, icterohepatitis, stomachache, vomiting and diarrhea, malaria, swollen welling abscess and sores, painful swelling from knocks and falls, bleeding due to external injury.	傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/佤族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000047	AKT1	AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA	AKT serine/threonine kinase 1
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000245	CYBB	AMCBX2; CGD; GP91-1; GP91-PHOX; GP91PHOX; IMD34; NOX2; p91-PHOX	cytochrome b-245 beta chain
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000435	PROM1	AC133; CD133; CORD12; MCDR2; MSTP061; PROML1; RP41; STGD4	prominin 1
TCMBANKGE000474	NCOA1	F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74	nuclear receptor coactivator 1
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000836	BACE1	ASP2; BACE; HSPC104	beta-secretase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE000980	SOX2	ANOP3; MCOPS3	SRY-box transcription factor 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001123	CTNNB1	CTNNB; EVR7; MRD19; NEDSDV; armadillo	catenin beta 1
TCMBANKGE001131	CASP9	APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56	caspase 9
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001164	RAF1	CMD1NN; CRAF; NS5; Raf-1; c-Raf	Raf-1 proto-oncogene, serine/threonine kinase
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001201	MAPK3	ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK	mitogen-activated protein kinase 3
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE001203	MAPK1	ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK	mitogen-activated protein kinase 1
TCMBANKGE001697	MMP1	CLG; CLGN	matrix metallopeptidase 1
TCMBANKGE003643	F7	SPCA	coagulation factor VII
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE005145	SDHC	CYB560; CYBL; PGL3; QPS1; SDH3	succinate dehydrogenase complex subunit C
TCMBANKGE010551	NES	Nbla00170	nestin
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE012217	MSI1	-	musashi RNA binding protein 1