Compound Summary

  Compound Information

TCMBANKIN019650

药名:	isoevodiamine
别名:	Evodiamine, (+)-; 21-METHYL-3,13,21-TRIAZAPENTACYCLO[11.8.0.0(2),(1)?.0?,?.0(1)?,(2)?]HENICOSA-2(10),4(9),5,7,15,17,19-HEPTAEN-14-ONE; SR-05000002159-2; MFCD06407824; E1012; 518-18-3; AS-15078; SR-05000002159; AC-24421; NCGC00163553-02; MolPort-003-983-878; ST51052658; AN-45498; N923; CCG-208627; d-Evodiamine; Evodiamine (Isoevodiamine); CHEMBL81925; SureCN682158; MCULE-3374039628; API0002668; 8,13,13b,14-Tetrahydro-14-methylindolo[2'3'-3,4]pyrido[2,1-b]quinazolin-5-[7H]-one; 21-methyl-3,13,21-triazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8,15(20),16,18-heptaen-14-one; CHEBI:95196; AKOS015894237; BRD-A68631409-001-01-3; (??)-Evodiamine; evodiamine, (S)-isomer; 21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20] henicosa-2(10),4,6,8,15,17,19-heptaen-14-one; Oprea1_236793; BCP9000671; Isoevodiamine; Indol(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13,13b,14-tetrahydro-14-methyl-, (S)-; BDBM50016250; LS-175304; PubChem18244; BC216230; Evodiamine;; SCHEMBL139349; NSC-258314; 5956-87-6; 14-METHYL-5-OXO-7,8-DIHYDRO-5H-INDOLO[2,3:3,4]PYRIDO[2,1-B]QUINAZOLIN-14-IUM-13-IDE; I05-0067; Indolo(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13,13b,14-tetrahydro-14-methyl-; (+/-)-Evodiamine; Indol(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13,13b,14-tetrahydro-14-methyl-, (13bS)-; s2382; AC1L461L; NSC258314; NCGC00163553-01; 8,13,13b,14-tetrahydro-14-methylindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7h)-one; AC1L9C8E; C19H17N3O
分子式:	C19H17N3O
Smiles:	CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3
成分:	HBIN030731
SymMap_id:	SMIT02000
TCMID_id:	24076
PubChem_id:	151289

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE009154	Radix Gentiae macrophyllae	秦艽			To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE006061	Fructus Evodiae	吴茱萸			1. To dispel cold and stop pain; 2. To pacify the liver and direct rebellious qi downward; 3. To stop vomiting/Dysentery, cold pain in stomach duct and abdomen, reverting yin headache, mounting qi , dysmenorrhea, beriberi with edema, hyperchlorhydria, cold-damp diarrhea.
TCMBANKHE006128	Radix Gentiae macrophyllae	秦艽			To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE004506/YEM-137	Radix Notoginseng|Panax notoginseng (Burk.) F, H. Chen ex C.Chow et al.	三七	三七	云南民族药物志：第一卷	To eliminate blood stasis, arrest bleeding, cause subsidence of swelling and alleviate pain./Hemoptysis, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, bleeding due to external injury, angina pectoris, stabbing pain in chest and abdomen, painful swelling from knocks and falls.	彝族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000017	MAPT	DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU	microtubule associated protein tau
TCMBANKGE000241	CASP8	ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5	caspase 8
TCMBANKGE000485	CASP4	ICE(rel)II; ICEREL-II; ICH-2; Mih1; Mih1/TX; TX	caspase 4
TCMBANKGE000540	CASP12	CASP-12; CASP12P1	caspase 12 (gene/pseudogene)
TCMBANKGE000665	CASP6	MCH2	caspase 6
TCMBANKGE000729	CASP1	ICE; IL1BC; P45	caspase 1
TCMBANKGE000820	CFLAR	CASH; CASP8AP1; CLARP; Casper; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT; c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; cFLIP	CASP8 and FADD like apoptosis regulator
TCMBANKGE001006	BAK1	BAK; BAK-LIKE; BCL2L7; CDN1	BCL2 antagonist/killer 1
TCMBANKGE001053	ABCG1	ABC8; WHITE1	ATP binding cassette subfamily G member 1
TCMBANKGE001097	HIF1A	HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78	hypoxia inducible factor 1 subunit alpha
TCMBANKGE001131	CASP9	APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56	caspase 9
TCMBANKGE001134	IRS1	HIRS-1	insulin receptor substrate 1
TCMBANKGE001155	CASP7	CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3	caspase 7
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001169	BCL2L1	BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52	BCL2 like 1
TCMBANKGE001173	MCL1	BCL2L3; EAT; MCL1-ES; MCL1L; MCL1S; Mcl-1; TM; bcl2-L-3; mcl1/EAT	MCL1 apoptosis regulator, BCL2 family member
TCMBANKGE001178	STAT3	ADMIO; ADMIO1; APRF; HIES	signal transducer and activator of transcription 3
TCMBANKGE001398	CASP10	ALPS2; FLICE2; MCH4	caspase 10
TCMBANKGE001862	TUBB4B	Beta2; LCAEOD; TUBB2; TUBB2C	tubulin beta 4B class IVb
TCMBANKGE003546	CARD18	ICEBERG; UNQ5804; pseudo-ICE	caspase recruitment domain family member 18
TCMBANKGE003625	SLC6A4	5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT	solute carrier family 6 member 4
TCMBANKGE005015	CASP5	ICE(rel)III; ICEREL-III; ICH-3	caspase 5
TCMBANKGE006697	CARD17	INCA	caspase recruitment domain family member 17
TCMBANKGE006736	BCL2L2	BCL-W; BCL2-L-2; BCLW; PPP1R51	BCL2 like 2
TCMBANKGE009127	BCL2A1	ACC-1; ACC-2; ACC1; ACC2; BCL2L5; BFL1; GRS; HBPA1	BCL2 related protein A1
TCMBANKGE009174	CARD8	CARDINAL; DACAR; DAKAR; NDPP; NDPP1; TUCAN	caspase recruitment domain family member 8
TCMBANKGE009760	BCL2L14	BCLG	BCL2 like 14
TCMBANKGE010096	CARD16	COP; COP1; PSEUDO-ICE	caspase recruitment domain family member 16
TCMBANKGE013371	PEA15	HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PED; PED-PEA15; PED/PEA15	proliferation and apoptosis adaptor protein 15
TCMBANKGE013390	CASP2	CASP-2; ICH1; NEDD-2; NEDD2; PPP1R57	caspase 2
TCMBANKGE013810	BOK	BCL2L9; BOKL	BCL2 family apoptosis regulator BOK