Compound Summary


  Compound Information

药名:

Codonopsine

别名:

codonopsine; C10137; AC1L9D48; (2R,3R,4R,5R)-2-(3,4-dimethoxyphenyl)-1,5-dimethylpyrrolidine-3,4-diol; CHEBI:3805; NCGC00160242-01; DTXSID60331887; 26989-20-8; (2R,3R,4R,5R)-2-(3,4-dimethoxyphenyl)-1,5-dimethyl-pyrrolidine-3,4-diol; STOCK1N-18670

分子式:

C14H21NO4

Smiles:

CC1C(C(C(N1C)C2=CC(=C(C=C2)OC)OC)O)O

成分:

HBIN021218

OB_score:

45.834236

CAS_id:

26989-20-8

SymMap_id:

SMIT09695;SMIT14725

TCMID_id:

3886

TCMSP_id:

MOL008395

PubChem_id:

442631


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003775 Radix Aconiti 川乌 To relieve rheumatic conditions and alleviate pain by warming the channels./Treatment of joint pain in rheumatic or rheumatoid arthritis, epigastric pain with cold sensation, or abdominal colic due to cold, also used as an analgesic in anaesthesis.
TCMBANKHE004102 Codonopsis tangshen 川党参 See Codonopsis pilosula./See Codonopsis pilosula .
TCMBANKHE004664 Radix Codonopsis pilosulae 党参 To reinforce qi and invigorate the function of the spleen and the lung./Spleen-stomach vacuity, reduced food intake and sloppy stool, lassitude in limbs, cough and asthma due to lung vacuity, shortness of breath and spontaneous sweating, qi-blood depletion.
TCMBANKHE005265 Codonopsis clematidea 新疆党参 See Codonopsis pilosula./See Codonopsis pilosula .
TCMBANKHE009133 Radix Codonopsis pilosulae 西党;党参 Treatment of weakness of the spleen and the lung manifested by shortness of breath, cough, palpitation, anorexia, loose stools, diabetes caused by internal heat;To reinforce qi and invigorate the function of the spleen and the lung./Treatment of weakness of the spleen and the lung manifested by shortness of breath, cough, palpitation, anorexia, loose stools, diabetes caused by internal heat;Spleen-stomach vacuity, reduced food intake and sloppy stool, lassitude in limbs, cough and asthma due to lung vacuity, shortness of breath and spontaneous sweating, qi-blood depletion.

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000425 DRD1 DADR; DRD1A dopamine receptor D1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE000965 CHRNA7 CHRNA7-2; NACHRA7 cholinergic receptor nicotinic alpha 7 subunit
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001194 ADRA2A ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 adrenoceptor alpha 2A
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE008056 ADRA2C ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR adrenoceptor alpha 2C
TCMBANKGE009256 SLC6A2 NAT1; NET; NET1; SLC6A5 solute carrier family 6 member 2
TCMBANKGE009455 CHRM5 HM5 cholinergic receptor muscarinic 5
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014625 OPRD1 DOP; DOR; DOR1; OPRD opioid receptor delta 1
TCMBANKGE014790 ADRB1 ADRB1R; B1AR; BETA1AR; FNSS2; RHR adrenoceptor beta 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1