Compound Summary

  Compound Information

TCMBANKIN022057

药名:	podophyllotoxin
别名:	Spectrum5_001368; AIDS002471; Spectrum2_000878; NCGC00022001-05; Prestwick0_000782; BPBio1_000974; RD4-6269; (-)-Podophyllotoxin; SPBio_002823; Spectrum_000199; AIDS-002471; BSPBio_002352; Podophyllotoxin 7; Podophyllinic acid lactone; Podophyllotoxin; KBio2_003247; Wartec; KBio2_000679; Warticon; UPCMLD-DP035:002; Condyline; NCGC00022001-09; DivK1c_000292; 1,3,3a,4,9,9a-Hexahydro-9-hydroxy-6,7-(methylenedioxy)-4-(3',4',5'-trimethoxyphenyl)benz(f)isobenzofuran-3-one; Naphtho[2,3-d]-1,3-dioxole-6-carboxylic acid, 5,6,7,8-tetrahydro-8-hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl-, .gamma.-lactone; Condylox; ST066914; 518-28-5; Condylox (TN); Podofilox (USAN); (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one; CCRIS 565; Spectrum4_000592; SPBio_000955; Prestwick_1018; 81125_FLUKA; D05529; Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-; BCBcMAP01_000165; 5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, [5R-(5.alpha.,5a.beta.,8a.alpha.,9.alpha.)]; ND-1185; SDCCGMLS-0066888.P001; ZINC03861806; KBio2_005815; NCGC00022001-08; Podophyllotoxin (8CI); C10874; NCI60_001981; Podophyllotoxin (BAN); 858447_ALDRICH; SMR000059121; P4405_SIGMA; AI3-50456; Prestwick2_000782; EINECS 208-250-4; Prestwick1_000782; Prestwick3_000782; UPCMLD-DP035:001; NSC 24818; IDI1_000292; KBioGR_001084; B18-5C; KBio1_000292; Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, [5R-(5.alpha.,5a.beta.,8a.alpha.,9.alpha.)]-; NSC24818; Podofilox [USAN]; NINDS_000292; (5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofurano[5,6-f][1,3]benzodioxol-8-one; MLS000069495; HSDB 7238; BSPBio_000884; Mayapple isolate; SMP1_000243; Podofilox; KBioSS_000679
分子式:	C22H22O8
Smiles:	COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O
成分:	HBIN040358
OB_score:	59.93769
CAS_id:	477-47-4
SymMap_id:	SMIT00382
TCMID_id:	17578
TCMSP_id:	MOL001714
PubChem_id:	10607

---

   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000117	Fructus Podophylli	小叶莲			Treatment of amenorrhea due to blood stasis, difficult labour, missed labour, retention of placenta./Treatment of amenorrhea due to blood stasis, difficult labour, missed labour, retention of placenta.
TCMBANKHE000174		八角莲
TCMBANKHE000581	Dysosma furfuracea
TCMBANKHE000761		华鬼臼
TCMBANKHE005429	Juniperus virginiana	北美圆柏
TCMBANKHE004059	Resi oliani	乳香			1. To invigorate blood and stop pain; 2. To reduce swelling/Pain in heart and abdomen, wind-damp impediment pain, amenorrhea, dysmenorrhea, stasis pain from knocks and falls, swelling toxin of welling abscess and flat abscess, intestinal welling abscess, enduring sores.
TCMBANKHE004155	Diphylleia grayi	山荷叶			See Diphylleia sinensis./See Diphylleia sinensis.
TCMBANKHE004282	Anthriscus sylvestris	峨参			To supplement spleen and boost qi, disperse swelling./Spleen vacuity and food distention, stomachache, lassitude in limbs, cough and asthma due to lung vacuity, senile nocturia, blood ejection from knocks and falls.
TCMBANKHE006215	Podophyllum peltatum	盾叶鬼臼
TCMBANKHE004772	Dysosma majorensis	白八角莲			To enrich yin and supplement kidney, clear lung and moisten dryness, resolve toxin and disperse swelling./Taxation damage and sinew bone pain, impotence, stomachache, innominate toxin swelling, knife wound.
TCMBANKHE009137	Sabina vulgaris	愁白;臭柏			To dispel wind and eliminate damp, quicken blood and relieve pain./Wind-damp impediment pain, itchy skin, headache, cough.
TCMBANKHE006974	Diphylleia sinensis	窝儿七			To dispel wind-damp, clear heat and cool blood, quicken blood and relieve pain, drain precipitation./Rheumatic arthritis, pain in lumbus and legs, steaming bone taxation fever, knocks and falls, menstrual disorder, painful bind in lesser-abdomen, swollen welling abscess.
TCMBANKHE008194	Podophyllum emodii	桃儿七			To dispel wind and eliminate damp, quicken blood and relieve pain, relieve cough and dispel phlegm./Wind-damp impediment pain, knocks and falls, menstrual disorder, dysmenorrhea, pain in stomach duct and abdomen, cough.
TCMBANKHE006009	Diphylleia cymosa	陕西窝儿七
TCMBANKHE008377	Dysosma subrosea	崇明八角莲
TCMBANKHE006560	Dysosma guangxiensis	广西八角莲
TCMBANKHE006689	Podocarpus gracilior	习罗汉松;西罗汉松
TCMBANKHE007160	Dysosma difformis	小八角莲			To transform phlegm and dissipate binds, dispel stasis and relieve pain, clear heat and resolve toxin./Swelling pain in throat, swollen welling abscess, clove sore, pneumonia, parotitis, poisonous snake bite, scrofula, knocks and falls.
TCMBANKHE008888	Sabina vulgaris	臭柏			To dispel wind and eliminate damp, quicken blood and relieve pain./Wind-damp impediment pain, itchy skin, headache, cough.
TCMBANKHE008587	Juniperus sabina	叉子圆柏
TCMBANKHE009095/YNS-1	Dysosma versipellis [Syn. Podophyllum versipelle ]|Dysosma versipellis (Hance) M. cheng ex Ying	鬼臼|八角莲	八角莲	云南药材标准：第一册	清热解毒，化痰散结，祛瘀消肿。用于咳嗽，咽喉肿痛，痈肿痔疮，瘰疬，跌打损伤，毒蛇咬伤。|See Dysosma pleiantha./See Dysosma pleiantha .
TCMBANKHE006454/YEM-371	Dysosma veitchii|Dysosma veitchii(Hemsl.et Wils.)Fu ex Ying	川八角莲	八角莲	云南民族药物志：第二卷	See Dysosma pleiantha ./See Dysosma pleiantha.	水族/彝族/壮族
TCMBANKHE008322/YNS-1/YEM-371	Dysosma pleiantha [Syn. Podophyllum pleianthum]|Dysosma versipellis (Hance) M. cheng ex Ying|Dysosma veitchii(Hemsl.et Wils.)Fu ex Ying	六角莲|八角莲|川八角莲	八角莲	云南药材标准：第一册|云南民族药物志：第二卷	清热解毒，化痰散结，祛瘀消肿。用于咳嗽，咽喉肿痛，痈肿痔疮，瘰疬，跌打损伤，毒蛇咬伤。|To transform phlegm and dissipate binds, dispel stasis and relieve pain, clear heat and resolve toxin./Cough, swelling pain in throat, scrofula, goiter and tuberculosis, swollen welling abscess, clove sore, poisonous snake bite, knocks and falls, pain in joints.	水族/彝族/壮族
TCMBANKHE006587/YEM-983	Radix Dipsaci|Dipsacus asperoides C.Y.Cheng et T.M.Ai	续断|川续断	续断	云南民族药物志：第五卷	For tonifying yang/See Dipsacus asperoides.	白族/布依族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/苗族/纳西族/彝族

---

   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

---

   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000051	IL1B	IL-1; IL1-BETA; IL1F2; IL1beta	interleukin 1 beta
TCMBANKGE000121	KCNH2	ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1	potassium voltage-gated channel subfamily H member 2
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000784	CALM3	CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3	calmodulin 3
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001085	MAPK8	JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c	mitogen-activated protein kinase 8
TCMBANKGE001184	RELA	CMCU; NFKB3; p65	RELA proto-oncogene, NF-kB subunit
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1