Compound Summary

  Compound Information

TCMBANKIN023322

药名:	tectorigenin
别名:	AK119808; 855130H9CO; KBio2_003809; Q-100619; K 251T; 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxychromen-4-one; DivK1c_006241; SCHEMBL351641; KBio1_001185; I07-0272; 5-18-05-00311 (Beilstein Handbook Reference); ISOFLAVONE, 4',5,7-TRIHYDROXY-6-METHOXY-; GTPL9738; KBioSS_001241; NP-005651; AX8245224; CHEBI:9429; ZINC899915; LMPK12050385; Tectorigenine; BDBM50241222; 548T776; Spectrum_000761; AC1NQZ4T; 4',5',7-trihydroxy-6-methoxyisoflavone; BG01592771; 4CN-1307; 548-77-6; Tectorigenin; tectorigenin ; AN-45829; 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-4-one; C10534; CS-0009804; 5,7,4'-Trihydroxy-6-methoxyisoflavone; DTXSID50203286; FT-0688353; 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromone; SpecPlus_000145; 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; KBio2_006377; MCULE-2089260732; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-; KBio2_001241; Y0198; 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one; AJ-24294; BRN 0305601; HY-N0792; 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4-chromenone; MFCD00597094; MolPort-003-665-854; 4',5,7-Trihydroxy-6-methoxyisoflavone; LS-84477; Tectorigenin, analytical standard; AKOS015897084; N1647; CHEMBL242740; UNII-855130H9CO
分子式:	C16H12O6
Smiles:	COC1=C(C2=C(C=C1O)OC=C(C2=O)C3=CC=C(C=C3)O)O
成分:	HBIN045833
OB_score:	28.409919
CAS_id:	548-77-6
SymMap_id:	SMIT00190
TCMID_id:	20885
TCMSP_id:	MOL003767
PubChem_id:	5281811

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000232		川射干
TCMBANKHE000482		白舌根
TCMBANKHE000956	flos puerariae lobatae	葛花			To relieve fever, to promote the production of body fluid,to facilitate eruption, and to arrest diarrhea./Treatment of fever, headache and stiffness of th nape in exogenous affections, thirst, diabetes, measles with inadequate eruption, acute dysentery or diarrhea, stiff and painful nape in hypertension.
TCMBANKHE002723	Dalbergia riparia
TCMBANKHE003222	Folium Viticis Negundo	牡荆叶			To counteract toxicity, and to induce expectoration, relieve cough and asthma./1. Oral administration of its eemulsion (0.52-1.73g.kg) exerts a strong expectorant effect in mice.2. Oral administration of its volatile oil (1.04g/kg) exerts a significant antitussive effect in mice with cough induced by inhalation of concentrated ammonia.3. Increasing the hypnotic effect of pentobarital sodium in mice.
TCMBANKHE007417	Flos Rosae chinensis	月季花			1. To invigorate blood and regulate menstruation; 2. To reduce swelling/Menstrual disorder, dysmenorrhea, knocks and falls, blood stasis swelling and pain, scrofula, swollen welling abscess, scalds.
TCMBANKHE005771	Ononis spinosa	刺芒柄花
TCMBANKHE006099		桑白皮			Lung heat cough asthma, water-rheum collecting lung, distention fullness and rapid asthma, edema, beriberi, inhibited urination.
TCMBANKHE004664	Radix Codonopsis pilosulae	党参			To reinforce qi and invigorate the function of the spleen and the lung./Spleen-stomach vacuity, reduced food intake and sloppy stool, lassitude in limbs, cough and asthma due to lung vacuity, shortness of breath and spontaneous sweating, qi-blood depletion.
TCMBANKHE004862	Lignum Dalbergiae odoriferae Rosewood	降香			To relieve pain by promoting the circulation of qi and blood, and to arrest bleeding./Shortening the plasma recalcification time in rabbits.
TCMBANKHE005497	Rhizoma Belamcandae	射干			To remove toxic heat, eliminate phlegm, and soothe the sore throat./Heat toxin and phlegm-fire stasis, swelling pain in throat, cough and asthma.
TCMBANKHE008045	Iris dichotoma	白花射干			To clear heat and resolve toxin, quicken blood and disperse swelling, relieve pain, relieve cough./Swelling pain in throat, gum swelling and pain, epidemic parotitis, mammary welling abscess, stomachache, hepatitis, liver spleen enlargement, lung heat cough, knocks and falls.
TCMBANKHE006641	Calculus Bovis	牛黄			To restore consciousness by reducing fire and eliminating phlegm , to relieve convulsions, and to counteract toxicity./Ardent fever, coma, fright epilepsy, convulsion, febrile diseases clouded spirit, wind stroke with orifice block, acute infant fright wind, swelling pain in throat, mouth and tongue sores, welling abscess and flat abscess with clove sore.
TCMBANKHE009133	Radix Codonopsis pilosulae	西党;党参			Treatment of weakness of the spleen and the lung manifested by shortness of breath, cough, palpitation, anorexia, loose stools, diabetes caused by internal heat;To reinforce qi and invigorate the function of the spleen and the lung./Treatment of weakness of the spleen and the lung manifested by shortness of breath, cough, palpitation, anorexia, loose stools, diabetes caused by internal heat;Spleen-stomach vacuity, reduced food intake and sloppy stool, lassitude in limbs, cough and asthma due to lung vacuity, shortness of breath and spontaneous sweating, qi-blood depletion.
TCMBANKHE008877	Iris germanica	德国鸢尾
TCMBANKHE006006/YEM-340	Iris tectorum|Iris tectorum Maxim.	鸢尾	鸢尾	云南民族药物志：第二卷	To clear heat and resolve toxin, dispel wind and disinhibit damp, disperse swelling and relieve pain./Swelling pain in throat, hepatitis, liver enlargement, cystitis, wind-damp pain, painful swelling from knocks and falls, sore and boil, itchy skin.	布依族/傣族/傈僳族/苗族/瑶族/彝族/壮族
TCMBANKHE004643/YEM-590/XU-716	Folium Mori|Morus alba L.|Morus alba	桑叶|桑	桑叶	云南民族药物志：第三卷|云南省昭通市盐津县	To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision.	阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000051	IL1B	IL-1; IL1-BETA; IL1F2; IL1beta	interleukin 1 beta
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000474	NCOA1	F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74	nuclear receptor coactivator 1
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000784	CALM3	CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3	calmodulin 3
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000907	SPDEF	PDEF; bA375E1.3	SAM pointed domain containing ETS transcription factor
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE000940	TERT	CMM9; DKCA2; DKCB4; EST2; PFBMFT1; TCS1; TP2; TRT; hEST2; hTRT	telomerase reverse transcriptase
TCMBANKGE000990	EGFR	ERBB; ERBB1; HER1; NISBD2; PIG61; mENA	epidermal growth factor receptor
TCMBANKGE000994	AKR1B1	ADR; ALDR1; ALR2; AR	aldo-keto reductase family 1 member B
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001125	IGF1	IGF; IGF-I; IGFI; MGF	insulin like growth factor 1
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE002334	TEP1	TLP1; TP1; TROVE1; VAULT2; p240	telomerase associated protein 1
TCMBANKGE002873	NPEPPS	AAP-S; MP100; PSA	aminopeptidase puromycin sensitive
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE006869	PTGER3	EP3; EP3-I; EP3-II; EP3-III; EP3-IV; EP3-VI; EP3e; PGE2-R; lnc003875	prostaglandin E receptor 3
TCMBANKGE008921	RXRA	NR2B1	retinoid X receptor alpha
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE013106	TIMP3	HSMRK222; K222; K222TA2; SFD	TIMP metallopeptidase inhibitor 3