Compound Summary

  Compound Information

TCMBANKIN023350

药名:	Isolicoflavonol
别名:	LMPK12111984; 94805-83-1; AIDS-060353; AIDS060353; CHEMBL457679; SR-01000765807; 5,7,4'-trihydroxy-3'-prenylflavonol; MLS000697735; BDBM50251003; 4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-; HMS2271L11; 9577AF; cid_5318585; SR-01000765807-2; 3,5,7-Trihydroxy-2-[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]-4H-1-benzopyran-4-one, 9CI; 3,5,7-trihydroxy-2-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]chromone; D0E5FV; AC1NSX1R; 4',5,7-Trihydroxy-3'-prenylflavonol; ZINC13130924; PGCKDCPTJAQQSQ-UHFFFAOYSA-N; MolPort-039-052-689; isolicoflavonol; BG01067669; SMR000470986; SCHEMBL5614138; 3,5,7-trihydroxy-2-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]-4-chromenone; 3,5,7-trihydroxy-2-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]chromen-4-one; 3,5,7-Trihydroxy-2-[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]-4H-1-benzopyran-4-one
分子式:	C20H18O6
Smiles:	CC(=CCC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)C
成分:	HBIN030868
OB_score:	45.169991
CAS_id:	94805-83-1
SymMap_id:	SMIT06780;SMIT16040
TCMID_id:	11487
TCMSP_id:	MOL004949
PubChem_id:	5318585

---

   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003728	Radix Glycyrrhizae	甘草			To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE005525	Macaranga conifera	针叶血桐
TCMBANKHE007721	Exocarpium Benincasae	冬瓜皮			1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.
TCMBANKHE007543/YEM-470/XU-386	Broussonetia papyrifera|Broussonetia papyrifera (L.)Vent.	构树	构树	云南民族药物志：第三卷|云南省昭通市盐津县	To dispel wind, brighten eyes, disinhibit urine./Wind papules, red eyes with gall, inhibited urination [=dysuria].	傣族/傈僳族/彝族

---

   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

---

   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1