Compound Summary

  Compound Information

TCMBANKIN023716

药名:	Laurifoline
别名:	(+)-Laurifoline; AKOS032962360; 7224-61-5; CHEMBL235429; MolPort-039-052-582; laurifoline; ZINC2007968
分子式:	C20H24NO4+
Smiles:	C[N+]1(CCC2=CC(=C(C3=C2C1CC4=CC(=C(C=C43)OC)O)O)OC)C
成分:	HBIN032759
OB_score:	22.961486
CAS_id:	6808-76-0
SymMap_id:	SMIT06282;SMIT16256
TCMID_id:	12566
TCMSP_id:	MOL004347
PubChem_id:	12305611

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003735	Herba Houttuyniae	鱼腥草			To remove toxic heat, to promote the drainage of pus, and to relieve dysuria./Pulmonary welling abscess with hacking of pus and blood, lung heat phlegm cough, pneumonia, chronic bronchitis, urinary tract infection, odynuria, chronic uterine cervical infection, leptospirosis, otitis media, cystitis, dysentery, mastitis, heat toxin sores, heat strangury.
TCMBANKHE004060	Zanthoxylum ailanthoides	樗叶花椒			To warm center, dry damp, kill worms, relieve pain./Cold pain in heart and abdomen, cold rheum, diarrhea, cold dysentery, damp impediment, red and white vaginal discharge, toothache.
TCMBANKHE006163	Lignum Pini Nodi	松节			1. To dispel wind and dry dampness; 2. To stop pain/Treatment of: 1. Wind-damp obstruction syndrome. Pine nodular branch (Songjie) is used with herbs that dispel wind and dampness. In acute arthritis with severe pain, Pine nodular branch (Songjie) is soaked in wine for drinking. 2. External injury pain. Pi
TCMBANKHE006130	Zanthoxylum ailanthoides	樗叶花椒皮			To dispel wind and eliminate damp, free network vessels and relieve pain, disinhibit urine./Wind-cold-damp impediment, pain in lumbus and knees, knocks and falls, abdominal pain and diarrhea, inhibited urination, toothache, eczema, scab and lichen.
TCMBANKHE008558	Zanthoxylum elephantiasis	厚皮花椒
TCMBANKHE004674/YEM-476	Cocculus laurifolius|Cocculus laurifolius DC.	衡州乌药|樟叶木防已	樟叶木防已	云南民族药物志：第三卷	To normalize qi and loosen chest, dispel wind and relieve pain./Hypertension, headache, mounting qi, abdominal pain, rheumatic pain in legs.	傣族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000633	ADRB2	ADRB2R; ADRBR; B2AR; BAR; BETA2AR	adrenoceptor beta 2
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000766	ACHE	ACEE; ARACHE; N-ACHE; YT	acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE005535	CHRM1	HM1; M1; M1R	cholinergic receptor muscarinic 1
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE006943	CHRM3	EGBRS; HM3; PBS	cholinergic receptor muscarinic 3
TCMBANKGE008702	OPRM1	LMOR; M-OR-1; MOP; MOR; MOR1; OPRM	opioid receptor mu 1
TCMBANKGE008921	RXRA	NR2B1	retinoid X receptor alpha
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1