Compound Summary

  Compound Information

TCMBANKIN023742

药名:	(2R,3R)-3-(4-hydroxy-3-methoxy-phenyl)-5-methoxy-2-methylol-2,3-dihydropyrano[5,6-h][1,4]benzodioxin-9-one
别名:	AIDS-227003; (2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-2,3-dihydropyrano[5,6-h][1,4]benzodioxin-9-one; 9H-pyrano[2,3-f]-1,4-benzodioxin-9-one, 2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-, (2R,3R)-; (2R,3R)-3-(4-hydroxy-3-methoxy-phenyl)-2-(hydroxymethyl)-5-methoxy-2,3-dihydropyrano[5,6-h][1,4]benzodioxin-9-one; AIDS227003; C09922
分子式:	C20H18O8
Smiles:	COC1=C(C=CC(=C1)C2C(OC3=C4C(=CC(=C3O2)OC)C=CC(=O)O4)CO)O
成分:	HBIN006400
OB_score:	68.825599
CAS_id:	76948-72-6
SymMap_id:	SMIT02701
TCMSP_id:	MOL000011
PubChem_id:	442510

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002776		白花菜子			Wind-cold sinew and bone numbness, aching pain in back and shoulder, lumbago, swelling pain due to external injury, bone tuberculosis, hemorrhoids and fistulas.
TCMBANKHE006781/YEM-333	Radix Saposhnikoviae divaricatae|Saposhnikovia divaricata (Turcz.)Schischk.	防风	防风	云南民族药物志：第二卷	To induce diaphoresis, to dispel wind, to alleviate rheumatic conditions, and to relieve spasm./Migraine, headache and generalized pain, common cold, rheumatoid arthritis, externally contracted wind-cold, wind-damp impediment pain, aching pain in joints, abdominal pain and diarrhea, intestinal wind bleeding, tetanus, wind papule itching, sores.	阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE005199/YEM-416/XU-321	Fructus Xanthii sibirici|Xanthium sibiricum Patrin ex Widder|Xanthium sibiricum	苍耳子|苍耳	苍耳子	云南民族药物志：第二卷|贵州省毕节市赫章县	To dispel wind and damp, and to relieve nasal obstruction./1. Lowering blood sugar, with similar mechanism as phenethyl biguanide ( DBI ). 2. Its chief poisonous component is rhamnose. The toxic effects in rats, guinea-pigs and rabbits by different routes of administration are similar. LD50 is 0.93g/kg in mice.	阿昌族/白族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/彝族/藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000121	KCNH2	ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1	potassium voltage-gated channel subfamily H member 2
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000474	NCOA1	F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74	nuclear receptor coactivator 1
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000784	CALM3	CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3	calmodulin 3
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE000979	KDR	CD309; FLK1; VEGFR; VEGFR2	kinase insert domain receptor
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE003643	F7	SPCA	coagulation factor VII
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1