Compound Summary

  Compound Information

TCMBANKIN024587

药名:	DLA
别名:	Lactic acid, D-; D-Lactic acid; (R)-Lactic acid; Propanoic acid, 2-hydroxy-,; CHEBI:42111; (-)-Lactic acid; EINECS 233-713-2; Poly-(L-lactide); 93578_FLUKA; Poly(L-lactide); 95468_FLUKA; (R)-2-Hydroxypropanoic acid; D-2-Hydroxypropanoic acid; (2R)-2-hydroxypropanoic acid; Propanoic acid, 2-hydroxy-, (2R)-; L0625_SIGMA; D-(-)-Lactic acid; P1566_SIGMA; (R)-2-Hydroxypropionsaeure; D-Milchsaeure; 1-Lactic acid; (R)-alpha-Hydroxypropionic acid; 531170_ALDRICH; (R)-(-)-Lactic acid; D-(−)-Lactic acid; Lactel BP-0600; C00256; D-2-Hydroxypropionic acid; (R)-2-Hydroxypropionic acid; Lactic acid (D); 94829_FLUKA; (R)-Milchsaeure; L-Lactide polymer; Propanoic acid, 2-hydroxy-, (R)-; (D)-(-)-Lactic acid
分子式:	C3H6O3
Smiles:	CC(C(=O)O)O
成分:	HBIN024298
OB_score:	44.506147
CAS_id:	50-21-5
SymMap_id:	SMIT04569
TCMSP_id:	MOL002301
PubChem_id:	61503

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE006313	Radix et Rhizoma Rhei	大黄			To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.
TCMBANKHE008629	pollen typhae	蒲黄			To arrest bleeding, to remove blood stasis, and to relieve dysuria./Hyperlipemia, angina pectoris, exudative eczema, bleeding, hemoptysis, spontaneous external bleeding, blood ejection, hematochezia, hematuria, flooding and spotting, bleeding due to external injury, pain in heart and abdomen, dysmenorrhea, postpartum bleeding, postpartum abdominal pain, blood strangury with inhibited pain.
TCMBANKHE006937/YEM-279	Stigma Maydis|Zea mays L.	玉米须|玉蜀黍	玉蜀黍	云南民族药物志：第二卷	1. To promote diuresis to relieve edema. 2. To promote choleresis and relieve jaundice. 3. To lower blood pressure. 4. To lower blood sugar level. 5. To stop bleeding. /Edema, dribbling urination, jaundice, cholecystitis, gallstones, hypertension, diabetes mellitus, galactostasis.	白族/傣族/佤族/彝族/藏族
TCMBANKHE004643/YEM-590/XU-716	Folium Mori|Morus alba L.|Morus alba	桑叶|桑	桑叶	云南民族药物志：第三卷|云南省昭通市盐津县	To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision.	阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE007363/YEM-744/XU-850	Radix et Rhizoma Rhei|Rheum palmatum L.|Rheum palmatum	大黄; 生锦纹; 生军|掌叶大黄	掌叶大黄	云南民族药物志：第四卷|西藏昌都地区芒康县	To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge.; Treatment of fever with constipation, retention of the feces and abdominal pain, dysentery with inadequate discharge from the bowels, jaundice caused by damp-heat, haematemesis, epistaxis, inflammation of eye and swelling of the throat due to heat in the blood, appendicitis with abdominal pain, boils, sores and abscess, amenorrhea due to blood stasis, traumatic injuries, hemorrhage from the upper gastrointestinal tract. External use for scalds and burns.Radixet Rhizoma Rhei (stir-fried with wine) Inflammation of the eye, swelling of the throat and painful swelling of the gums. Radix et Rhizoma Rhei (prepared) Boils, sores and abscess. Radix et Rhizoma Rhei (carbonized) Hemorrhage with blood stasis due to heat in the blood./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.; 1. Sennoside A is the component for purgation.2. Promoting biliary secretion and enhancing the amount of bilirubin and bile acid.3. Rhein and Emodin exert bacteriostatic effect by inhibting the synthesis of DNA, RNA and protein in bacteria4. Emodin is a component for hypotensive5. Oral use of its extract reduces the raio of serum cholesterol and total phospholipid in rabbits with hypercholesterolemia.6. Chrysophanol, an other active component, exerts a hemostatic effect.	阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000212	GRIN1	GluN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1	glutamate ionotropic receptor NMDA type subunit 1
TCMBANKGE000469	CTSD	CLN10; CPSD; HEL-S-130P	cathepsin D
TCMBANKGE000706	ARG1	-	arginase 1
TCMBANKGE000717	CTH	-	cystathionine gamma-lyase
TCMBANKGE000766	ACHE	ACEE; ARACHE; N-ACHE; YT	acetylcholinesterase (Cartwright blood group)
TCMBANKGE000830	GOT2	KAT4; KATIV; KYAT4; mitAAT	glutamic-oxaloacetic transaminase 2
TCMBANKGE000851	PKM	CTHBP; HEL-S-30; OIP3; PK3; PKM2; TCB; THBP1; p58	pyruvate kinase M1/2
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000928	RRM1	R1; RIR1; RR1	ribonucleotide reductase catalytic subunit M1
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001142	CHDH	-	choline dehydrogenase
TCMBANKGE001171	SRC	ASV; SRC1; THC6; c-SRC; p60-Src	SRC proto-oncogene, non-receptor tyrosine kinase
TCMBANKGE001176	CAT	-	catalase
TCMBANKGE001191	GRIA1	GLUH1; GLUR1; GLURA; GluA1; HBGR1	glutamate ionotropic receptor AMPA type subunit 1
TCMBANKGE001468	PHYKPL	AGXT2L2; PHLU	5-phosphohydroxy-L-lysine phospho-lyase
TCMBANKGE001522	ALAS2	ALAS-E; ALASE; ANH1; ASB; SIDBA1; XLDPP; XLEPP; XLSA	5'-aminolevulinate synthase 2
TCMBANKGE001890	ME2	ODS1	malic enzyme 2
TCMBANKGE001977	F13A1	F13A	coagulation factor XIII A chain
TCMBANKGE002135	ACAA2	DSAEC	acetyl-CoA acyltransferase 2
TCMBANKGE002540	AARS1	AARS; CMT2N; EIEE29	alanyl-tRNA synthetase 1
TCMBANKGE003342	GATM	AGAT; AT; CCDS3	glycine amidinotransferase
TCMBANKGE003365	ALDH9A1	ALDH4; ALDH7; ALDH9; E3; TMABA-DH; TMABADH; TMABALDH	aldehyde dehydrogenase 9 family member A1
TCMBANKGE003476	OAT	GACR; HOGA; OATASE; OKT	ornithine aminotransferase
TCMBANKGE003733	AGXT2	AGT2; BAIBA; DAIBAT	alanine--glyoxylate aminotransferase 2
TCMBANKGE004181	GLB1	EBP; ELNR1; MPS4B	galactosidase beta 1
TCMBANKGE004437	PYGM	GSD5	glycogen phosphorylase, muscle associated
TCMBANKGE004751	GPHN	GEPH; GPH; GPHRYN; HKPX1; MOCODC	gephyrin
TCMBANKGE005226	LDHA	GSD11; HEL-S-133P; LDHM; PIG19	lactate dehydrogenase A
TCMBANKGE005992	GALE	SDR1E1	UDP-galactose-4-epimerase
TCMBANKGE006454	PKLR	PK1; PKL; PKRL; RPK	pyruvate kinase L/R
TCMBANKGE006674	KYNU	KYNUU; VCRL2	kynureninase
TCMBANKGE006886	ADH1A	ADH1	alcohol dehydrogenase 1A (class I), alpha polypeptide
TCMBANKGE007176	GCAT	KBL	glycine C-acetyltransferase
TCMBANKGE008126	TPI1	HEL-S-49; TIM; TPI; TPID	triosephosphate isomerase 1
TCMBANKGE008570	PIPOX	LPIPOX	pipecolic acid and sarcosine oxidase
TCMBANKGE008686	CDC25B	-	cell division cycle 25B
TCMBANKGE008718	PRSS3	MTG; PRSS4; T9; TRY3; TRY4	serine protease 3
TCMBANKGE009119	ME1	HUMNDME; MES	malic enzyme 1
TCMBANKGE009361	GPT	AAT1; ALT1; GPT1	glutamic--pyruvic transaminase
TCMBANKGE009373	MMP8	CLG1; HNC; MMP-8; PMNL-CL	matrix metallopeptidase 8
TCMBANKGE009666	SLC36A1	Dct1; LYAAT1; PAT1; TRAMD3	solute carrier family 36 member 1
TCMBANKGE010079	ADSS1	ADSSL1; MPD5	adenylosuccinate synthase 1
TCMBANKGE010235	AGXT	AGT; AGT1; AGXT1; PH1; SPAT; SPT; TLH6	alanine--glyoxylate and serine--pyruvate aminotransferase
TCMBANKGE010652	PDHB	PDHBD; PDHE1-B; PDHE1B; PHE1B	pyruvate dehydrogenase E1 subunit beta
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE012101	GOT1	AST1; ASTQTL1; GIG18; cAspAT; cCAT	glutamic-oxaloacetic transaminase 1
TCMBANKGE012926	SLC25A13	ARALAR2; CITRIN; CTLN2; NICCD	solute carrier family 25 member 13
TCMBANKGE012981	LDHB	HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5	lactate dehydrogenase B
TCMBANKGE013570	CELA3A	ELA3; ELA3A	chymotrypsin like elastase 3A
TCMBANKGE014015	BCHE	BCHED; CHE1; CHE2; E1	butyrylcholinesterase
TCMBANKGE014050	GABRA1	ECA4; EIEE19; EJM; EJM5	gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014260	GNMT	HEL-S-182mP	glycine N-methyltransferase
TCMBANKGE014498	XDH	XAN1; XO; XOR	xanthine dehydrogenase
TCMBANKGE014656	ABAT	GABA-AT; GABAT; NPD009	4-aminobutyrate aminotransferase
TCMBANKGE014940	NFS1	HUSSY-08; IscS; NIFS	NFS1 cysteine desulfurase
TCMBANKGE015000	BHMT	BHMT1; HEL-S-61p	betaine--homocysteine S-methyltransferase